Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis

Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms. During Zn limitation, specialized enzymes called metallochaperones are predicted to allocate Zn to specific metalloproteins. This function has been putatively assigned to G3E GTPase COG0523 proteins,...

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Bibliographic Details
Published in:	Cell Vol. 185; no. 12; p. 2148
Main Authors:	Weiss, Andy, Murdoch, Caitlin C, Edmonds, Katherine A, Jordan, Matthew R, Monteith, Andrew J, Perera, Yasiru R, Rodríguez Nassif, Aslin M, Petoletti, Amber M, Beavers, William N, Munneke, Matthew J, Drury, Sydney L, Krystofiak, Evan S, Thalluri, Kishore, Wu, Hongwei, Kruse, Angela R S, DiMarchi, Richard D, Caprioli, Richard M, Spraggins, Jeffrey M, Chazin, Walter J, Giedroc, David P, Skaar, Eric P
Format:	Journal Article
Language:	English
Published:	United States 09.06.2022
Subjects:	Animals GTP Phosphohydrolases - metabolism Homeostasis Metallochaperones - metabolism Metalloendopeptidases - metabolism Metalloproteins - genetics Mice Zebrafish - metabolism Zinc - metabolism metalloprotein zf-C6H2 CBWD ZNG1 metallochaperone zinc finger GTPase zinc COG0523 METAP1
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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