The balance between conventional and unconventional T follicular helper cells influences autoreactive B cell responses

Invariant natural killer T (iNKT) cells are activated by glycolipids presented on CD1d. When iNKT cells interact with and activate B cells, they can differentiate into iNKT follicular helper (iNKTfh) cells, and here, we investigate how this, in turn, regulates conventional T follicular helper (Tfh)...

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Bibliographic Details
Published in:	Cell reports (Cambridge) Vol. 44; no. 5; p. 115602
Main Authors:	He, Chenfei, Wang, Shan, Moreews, Marion, Pei, Shengduo, Chen, Guangchun, Li, Quan-Zhen, Del Monte Monge, Alberto, Ramiro, Almudena R., Cai, Curtis, Gaya, Mauro, Barral, Patricia, Buggert, Marcus, Batista, Facundo D., Karlsson, Mikael C.I.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 27.05.2025 Elsevier
Subjects:	Animals Antigens, CD1d - immunology Antigens, CD1d - metabolism apoptotic cells Autoantibodies - immunology autoimmune disease Autoimmunity B-Lymphocytes - immunology CD1d Cell Differentiation CP: Immunology germinal center Lupus Erythematosus, Systemic - immunology Lymphocyte Activation - immunology Mice Mice, Inbred C57BL Natural Killer T-Cells - immunology T follicular helper cells T Follicular Helper Cells - immunology T-Lymphocytes, Helper-Inducer - immunology CP: Immunology CD1d germinal center apoptotic cells autoimmune disease T follicular helper cells
ISSN:	2211-1247, 2211-1247
Online Access:	Get full text
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