Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

Immune cells and epithelium form sophisticated barrier systems in symbiotic relationships with microbiota. Evidence suggests that immune cells can sense microbes through intact barriers, but regulation of microbial commensalism remain largely unexplored. Here, we uncovered spatial compartmentalizati...

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Vydáno v:	Cell Ročník 176; číslo 5; s. 982
Hlavní autoři:	Kobayashi, Tetsuro, Voisin, Benjamin, Kim, Do Young, Kennedy, Elizabeth A, Jo, Jay-Hyun, Shih, Han-Yu, Truong, Amanda, Doebel, Thomas, Sakamoto, Keiko, Cui, Chang-Yi, Schlessinger, David, Moro, Kazuyo, Nakae, Susumu, Horiuchi, Keisuke, Zhu, Jinfang, Leonard, Warren J, Kong, Heidi H, Nagao, Keisuke
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 21.02.2019
Témata:	Animals Bacteria - metabolism Cytokines - metabolism Epithelium - immunology Hair Follicle - metabolism Hair Follicle - microbiology Immunity, Innate Interleukin-7 - metabolism Lymphocytes - immunology Lymphocytes - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Microbiota - immunology Receptors, CCR6 - metabolism Receptors, Notch - metabolism Receptors, Tumor Necrosis Factor - metabolism Sebaceous Glands - immunology Sebaceous Glands - metabolism Sebaceous Glands - microbiology Skin - metabolism Skin Physiological Phenomena Symbiosis Thymic Stromal Lymphopoietin
ISSN:	1097-4172, 1097-4172
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