A genome-wide association study of the human metabolome in a community-based cohort

Because metabolites are hypothesized to play key roles as markers and effectors of cardiometabolic diseases, recent studies have sought to annotate the genetic determinants of circulating metabolite levels. We report a genome-wide association study (GWAS) of 217 plasma metabolites, including >100...

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Bibliographic Details

Published in:	Cell metabolism Vol. 18; no. 1; p. 130
Main Authors:	Rhee, Eugene P, Ho, Jennifer E, Chen, Ming-Huei, Shen, Dongxiao, Cheng, Susan, Larson, Martin G, Ghorbani, Anahita, Shi, Xu, Helenius, Iiro T, O'Donnell, Christopher J, Souza, Amanda L, Deik, Amy, Pierce, Kerry A, Bullock, Kevin, Walford, Geoffrey A, Vasan, Ramachandran S, Florez, Jose C, Clish, Clary, Yeh, J-R Joanna, Wang, Thomas J, Gerszten, Robert E
Format:	Journal Article
Language:	English
Published:	United States 02.07.2013
Subjects:	Aged Cholesterol Esters - metabolism Cohort Studies Community Participation Female Genome, Human - genetics Genome-Wide Association Study Humans Male Massachusetts Metabolome - genetics Middle Aged Transaminases - genetics Transaminases - metabolism Triglycerides - metabolism
ISSN:	1932-7420, 1932-7420
Online Access:	Get more information
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