The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

Non-coding regions comprise most of the human genome and harbor a significant fraction of risk alleles for neuropsychiatric diseases, yet their functions remain poorly defined. We created a high-resolution map of non-coding elements involved in human cortical neurogenesis by contrasting chromatin ac...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Cell Ročník 172; číslo 1-2; s. 289
Hlavní autoři:	de la Torre-Ubieta, Luis, Stein, Jason L, Won, Hyejung, Opland, Carli K, Liang, Dan, Lu, Daning, Geschwind, Daniel H
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 11.01.2018
Témata:	Cell Line Cells, Cultured Cerebral Cortex - cytology Cerebral Cortex - embryology Cerebral Cortex - metabolism Chromatin - genetics Chromatin - metabolism Chromatin Assembly and Disassembly Enhancer Elements, Genetic Female Gene Expression Regulation, Developmental Humans Male Neurogenesis Neurons - cytology Neurons - metabolism Polymorphism, Genetic Receptor, Fibroblast Growth Factor, Type 2 - genetics Receptor, Fibroblast Growth Factor, Type 2 - metabolism T-Box Domain Proteins - genetics T-Box Domain Proteins - metabolism human neocortical development evolution enhancers chromatin transcription factors ATAC-seq
ISSN:	1097-4172, 1097-4172
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!