Mechanisms of pathological scarring: Role of myofibroblasts and current developments

ABSTRACT Myofibroblasts play a key role in the wound‐healing process, promoting wound closure and matrix deposition. These cells normally disappear from granulation tissue by apoptosis after wound closure, but under some circumstances, they persist and may contribute to pathological scar formation....

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Wound repair and regeneration Jg. 19; H. s1; S. s10 - s15
Hauptverfasser:	Sarrazy, Vincent, Billet, Fabrice, Micallef, Ludovic, Coulomb, Bernard, Desmoulière, Alexis
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Malden, USA Blackwell Publishing Inc 01.09.2011
Schlagworte:	Cicatrix - physiopathology Cicatrix, Hypertrophic - physiopathology Granulation Tissue - physiology Humans Keloid - physiopathology Liver - physiopathology Myofibroblasts - cytology Myofibroblasts - physiology Neoplasms - physiopathology Stress, Mechanical Transforming Growth Factor beta1 - physiology Wound Healing - physiology
ISSN:	1067-1927, 1524-475X, 1524-475X
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!