Molecular mechanisms involved in inflammasome activation

Germline-encoded pattern recognition receptors (PRRs) sense microbial or endogenous products released from damaged or dying cells and trigger innate immunity. In most cases, sensing of these signals is coupled to signal transduction pathways that lead to transcription of immune response genes that c...

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Bibliographic Details

Published in:	Trends in cell biology Vol. 19; no. 9; pp. 455 - 464
Main Authors:	Bryant, Clare, Fitzgerald, Katherine A.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.09.2009
Subjects:	Adaptor Proteins, Signal Transducing - metabolism Animals Apoptosis Regulatory Proteins - metabolism Caspase 1 - metabolism Humans Inflammation - genetics Inflammation - immunology Inflammation - metabolism Pathology Receptors, G-Protein-Coupled - immunology Receptors, G-Protein-Coupled - metabolism Signal Transduction
ISSN:	0962-8924, 1879-3088, 1879-3088
Online Access:	Get full text
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