Molecular mechanisms involved in inflammasome activation

Germline-encoded pattern recognition receptors (PRRs) sense microbial or endogenous products released from damaged or dying cells and trigger innate immunity. In most cases, sensing of these signals is coupled to signal transduction pathways that lead to transcription of immune response genes that c...

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Vydané v:	Trends in cell biology Ročník 19; číslo 9; s. 455 - 464
Hlavní autori:	Bryant, Clare, Fitzgerald, Katherine A.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Ltd 01.09.2009
Predmet:	Adaptor Proteins, Signal Transducing - metabolism Animals Apoptosis Regulatory Proteins - metabolism Caspase 1 - metabolism Humans Inflammation - genetics Inflammation - immunology Inflammation - metabolism Pathology Receptors, G-Protein-Coupled - immunology Receptors, G-Protein-Coupled - metabolism Signal Transduction
ISSN:	0962-8924, 1879-3088, 1879-3088
On-line prístup:	Získať plný text
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