Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer’s Disease, and Vascular Dementia in Older Adults

A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Al...

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Vydané v:Brain sciences Ročník 7; číslo 2; s. 22
Hlavní autori: Gallaway, Patrick, Miyake, Hiroji, Buchowski, Maciej, Shimada, Mieko, Yoshitake, Yutaka, Kim, Angela, Hongu, Nobuko
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Switzerland MDPI AG 20.02.2017
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ISSN:2076-3425, 2076-3425
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Abstract A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Alzheimer’s disease, vascular dementia, and mild cognitive impairment. We also provide evidence of PA’s role in reducing the risks of these diseases and helping to improve cognitive outcomes in older adults. Finally, we describe some potential mechanisms by which this protective effect occurs, providing guidelines for future research.
AbstractList A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Alzheimer’s disease, vascular dementia, and mild cognitive impairment. We also provide evidence of PA’s role in reducing the risks of these diseases and helping to improve cognitive outcomes in older adults. Finally, we describe some potential mechanisms by which this protective effect occurs, providing guidelines for future research.
Author Gallaway, Patrick
Kim, Angela
Miyake, Hiroji
Buchowski, Maciej
Yoshitake, Yutaka
Shimada, Mieko
Hongu, Nobuko
AuthorAffiliation 3 Department of Medicine, Vanderbilt University, Nashville, TN 37232-5280, USA; maciej.buchowski@vanderbilt.edu
1 Department of Nutritional Sciences, The University of Arizona, Tucson, AZ 85721-0038, USA; gallaway@email.arizona.edu (P.J.G.); ask1@email.arizona.edu (A.S.K.)
5 National Institute of Fitness & Sport in Kanoya, Kagoshima 891-2311, Japan; yositake@nifs-k.ac.jp
4 Chiba Prefectural University of Health Sciences, Chiba 261-0014, Japan; mieko.shimada@cpuhs.ac.jp
2 Nishinomiya Kyoritsu Neurosurgical Hospital, Hyogo 663-8211, Japan; miyake@nk-hospital.or.jp
AuthorAffiliation_xml – name: 1 Department of Nutritional Sciences, The University of Arizona, Tucson, AZ 85721-0038, USA; gallaway@email.arizona.edu (P.J.G.); ask1@email.arizona.edu (A.S.K.)
– name: 4 Chiba Prefectural University of Health Sciences, Chiba 261-0014, Japan; mieko.shimada@cpuhs.ac.jp
– name: 5 National Institute of Fitness & Sport in Kanoya, Kagoshima 891-2311, Japan; yositake@nifs-k.ac.jp
– name: 2 Nishinomiya Kyoritsu Neurosurgical Hospital, Hyogo 663-8211, Japan; miyake@nk-hospital.or.jp
– name: 3 Department of Medicine, Vanderbilt University, Nashville, TN 37232-5280, USA; maciej.buchowski@vanderbilt.edu
Author_xml – sequence: 1
  givenname: Patrick
  surname: Gallaway
  fullname: Gallaway, Patrick
– sequence: 2
  givenname: Hiroji
  surname: Miyake
  fullname: Miyake, Hiroji
– sequence: 3
  givenname: Maciej
  surname: Buchowski
  fullname: Buchowski, Maciej
– sequence: 4
  givenname: Mieko
  surname: Shimada
  fullname: Shimada, Mieko
– sequence: 5
  givenname: Yutaka
  surname: Yoshitake
  fullname: Yoshitake, Yutaka
– sequence: 6
  givenname: Angela
  surname: Kim
  fullname: Kim, Angela
– sequence: 7
  givenname: Nobuko
  surname: Hongu
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/28230730$$D View this record in MEDLINE/PubMed
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Keywords Alzheimer’s disease
dementia
health
mild cognitive impairment
aging
cognitive decline
physical activity
Language English
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Snippet A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we...
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SubjectTerms Aging
Alzheimer's disease
Cognition & reasoning
cognitive decline
Dementia
health
mild cognitive impairment
Neurodegeneration
physical activity
Review
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Title Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer’s Disease, and Vascular Dementia in Older Adults
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