Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons

Disrupting particular mitochondrial fission and fusion proteins leads to the death of specific neuronal populations; however, the normal functions of mitochondrial fission in neurons are poorly understood, especially in vivo , which limits the understanding of mitochondrial changes in disease. Alter...

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Bibliographic Details
Published in:	Cell death & disease Vol. 6; no. 4; p. e1725
Main Authors:	Shields, L Y, Kim, H, Zhu, L, Haddad, D, Berthet, A, Pathak, D, Lam, M, Ponnusamy, R, Diaz-Ramirez, L G, Gill, T M, Sesaki, H, Mucke, L, Nakamura, K
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16.04.2015 Springer Nature B.V Nature Publishing Group
Subjects:	13 13/106 13/109 14/1 14/19 14/33 14/35 14/63 38/1 631/45/612/1240 631/57/1464 631/80/82 64 64/110 64/60 692/699/375 82 82/1 82/51 Animals Antibodies Axons - physiology Biochemistry Biomedical and Life Sciences CA1 Region, Hippocampal - metabolism CA1 Region, Hippocampal - physiology Cell Biology Cell Culture Dynamins - deficiency Dynamins - genetics Dynamins - metabolism Dynamins - physiology Energy Metabolism Female Immunology Life Sciences Male Mice Mice, Knockout Mitochondria - metabolism Neurons - metabolism Neurons - physiology Original original-article Synapses - physiology
ISSN:	2041-4889, 2041-4889
Online Access:	Get full text
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