SARS‐CoV‐2 targets neurons of 3D human brain organoids

COVID‐19 pandemic caused by SARS‐CoV‐2 infection is a public health emergency. COVID‐19 typically exhibits respiratory illness. Unexpectedly, emerging clinical reports indicate that neurological symptoms continue to rise, suggesting detrimental effects of SARS‐CoV‐2 on the central nervous system (CN...

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Bibliographic Details
Published in:	The EMBO journal Vol. 39; no. 20; pp. e106230 - n/a
Main Authors:	Ramani, Anand, Müller, Lisa, Ostermann, Philipp N, Gabriel, Elke, Abida‐Islam, Pranty, Müller‐Schiffmann, Andreas, Mariappan, Aruljothi, Goureau, Olivier, Gruell, Henning, Walker, Andreas, Andrée, Marcel, Hauka, Sandra, Houwaart, Torsten, Dilthey, Alexander, Wohlgemuth, Kai, Omran, Heymut, Klein, Florian, Wieczorek, Dagmar, Adams, Ortwin, Timm, Jörg, Korth, Carsten, Schaal, Heiner, Gopalakrishnan, Jay
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 15.10.2020 Springer Nature B.V EMBO Press John Wiley and Sons Inc
Subjects:	Abnormalities Animals Axons Betacoronavirus - physiology Brain Brain - virology brain organoids Cell Death Central nervous system Chlorocebus aethiops Coronaviruses COVID-19 EMBO23 EMBO24 EMBO27 Exposure Humans Life Sciences Nervous system Nervous System Diseases - virology Neuroimaging Neurons Neurons - virology Neurotoxicity Organoids Pandemics Phosphorylation Public health SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Tau pathology Tau protein tau Proteins - metabolism Tropism Vero Cells Viral diseases Tau pathology brain organoids cell death SARS‐CoV-2 neurons SARS-CoV-2
ISSN:	0261-4189, 1460-2075, 1460-2075
Online Access:	Get full text
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