Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

Nuclear pore complexes have recently been shown to play roles in gene activation; however their potential involvement in metazoan transcription remains unclear. Here we show that the nucleoporins Sec13, Nup98, and Nup88, as well as a group of FG-repeat nucleoporins, bind to the Drosophila genome at...

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Veröffentlicht in:	Cell Jg. 140; H. 3; S. 372
Hauptverfasser:	Capelson, Maya, Liang, Yun, Schulte, Roberta, Mair, William, Wagner, Ulrich, Hetzer, Martin W
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 05.02.2010
Schlagworte:	Animals Chromatin - metabolism Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - metabolism Gene Expression Regulation Heat-Shock Response Nuclear Pore Complex Proteins - metabolism RNA Polymerase II - metabolism Transcription, Genetic
ISSN:	1097-4172, 1097-4172
Online-Zugang:	Weitere Angaben
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