Tissue factor as a link between inflammation and coagulation

Due to its receptor activity for factor VII, tissue factor (TF) is primary initiator of the blood coagulation cascade and ensures rapid hemostasis in case of organ damage. Inflammatory cytokines, such as tumor necrosis factor-α or interleukins, strongly induce expression of both full-length TF as we...

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Bibliographic Details
Published in:	Trends in cardiovascular medicine Vol. 26; no. 4; pp. 297 - 303
Main Authors:	Witkowski, Marco, Landmesser, Ulf, Rauch, Ursula
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.05.2016 Elsevier Limited
Subjects:	Acute coronary syndromes Alternative Splicing Angiogenesis Animals Blood clots Blood Coagulation Cancer Cardiovascular Coagulation Diabetes Endothelium Gene Expression Regulation Homeostasis Humans Inflammation Inflammation - blood Inflammation - genetics Inflammation Mediators - blood Protein Conformation Protein folding Signal Transduction Thromboplastin - chemistry Thromboplastin - genetics Thromboplastin - metabolism Thrombosis Tissue factor Vessel Vessel Inflammation Tissue factor Coagulation Endothelium Tissue Factor
ISSN:	1050-1738, 1873-2615, 1873-2615
Online Access:	Get full text
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