Developing the OpenFlexure Microscope towards medical use: technical and social challenges of developing globally accessible hardware for healthcare

The OpenFlexure Microscope is an accessible, three-dimensional-printed robotic microscope, with sufficient image quality to resolve diagnostic features including parasites and cancerous cells. As access to lab-grade microscopes is a major challenge in global healthcare, the OpenFlexure Microscope ha...

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Vydáno v:Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences Ročník 382; číslo 2274; s. 20230257
Hlavní autoři: Knapper, Joe, Whiteford, Freya, Rosen, Daniel, Wadsworth, William, Stirling, Julian, Mkindi, Catherine, Mduda, Joram, Sanga, Valerian L, Nyakyi, Paul T, Mboa Nkoudou, Thomas Hervé, Jafsia, Elisée, Fadanka, Stephane, Hummel, Kelsey, Anandasabapathy, Sharmila, Bowman, Richard
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 09.07.2024
Témata:
Delivery of Health Care
Equipment Design
Humans
Microscopy - instrumentation
Microscopy - methods
Point-of-Care Systems
Printing, Three-Dimensional - instrumentation
Robotics - instrumentation
Robotics - statistics & numerical data
Robotics - trends
Software
global health
open source
microscopy
pathology
ISSN:1471-2962, 1471-2962
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Popis
Shrnutí:The OpenFlexure Microscope is an accessible, three-dimensional-printed robotic microscope, with sufficient image quality to resolve diagnostic features including parasites and cancerous cells. As access to lab-grade microscopes is a major challenge in global healthcare, the OpenFlexure Microscope has been developed to be manufactured, maintained and used in remote environments, supporting point-of-care diagnosis. The steps taken in transforming the hardware and software from an academic prototype towards an accepted medical device include addressing technical and social challenges, and are key for any innovation targeting improved effectiveness in low-resource healthcare. This article is part of the Theo Murphy meeting issue 'Open, reproducible hardware for microscopy'.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1471-2962
1471-2962
DOI:10.1098/rsta.2023.0257