LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain

The leucine‐rich repeat kinase 2 (LRRK2) gene was recently found to have multiple mutations that are causative for autosomal dominant inherited Parkinson's disease (PD). Previously, we used Northern blot analysis to show that this gene was expressed in the cerebellum, cerebral cortex, medulla,...

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Vydané v:	The European journal of neuroscience Ročník 23; číslo 3; s. 659 - 666
Hlavní autori:	Simón-Sánchez, Javier, Herranz-Pérez, Vicente, Olucha-Bordonau, Francisco, Pérez-Tur, Jordi
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Oxford, UK Blackwell Publishing Ltd 01.02.2006
Predmet:	Animals Brain - metabolism Brain - pathology Brain Mapping dardarin Disease Models, Animal expression Gene Expression - physiology In Situ Hybridization - methods Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Male Mice mousebrain Parkinson Disease - metabolism Parkinson Disease - pathology Parkinson's disease Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism RNA, Messenger - metabolism
ISSN:	0953-816X, 1460-9568
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