LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain

The leucine‐rich repeat kinase 2 (LRRK2) gene was recently found to have multiple mutations that are causative for autosomal dominant inherited Parkinson's disease (PD). Previously, we used Northern blot analysis to show that this gene was expressed in the cerebellum, cerebral cortex, medulla,...

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Bibliographic Details
Published in:	The European journal of neuroscience Vol. 23; no. 3; pp. 659 - 666
Main Authors:	Simón-Sánchez, Javier, Herranz-Pérez, Vicente, Olucha-Bordonau, Francisco, Pérez-Tur, Jordi
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.02.2006
Subjects:	Animals Brain - metabolism Brain - pathology Brain Mapping dardarin Disease Models, Animal expression Gene Expression - physiology In Situ Hybridization - methods Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Male Mice mousebrain Parkinson Disease - metabolism Parkinson Disease - pathology Parkinson's disease Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism RNA, Messenger - metabolism
ISSN:	0953-816X, 1460-9568
Online Access:	Get full text
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