BAF250B‐Associated SWI/SNF Chromatin‐Remodeling Complex Is Required to Maintain Undifferentiated Mouse Embryonic Stem Cells

Whether SWI/SNF chromatin remodeling complexes play roles in embryonic stem (ES) cells remains unknown. Here we show that SWI/SNF complexes are present in mouse ES cells, and their composition is dynamically regulated upon induction of ES cell differentiation. For example, the SWI/SNF purified from...

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Bibliographic Details
Published in:	Stem cells (Dayton, Ohio) Vol. 26; no. 5; pp. 1155 - 1165
Main Authors:	Yan, Zhijiang, Wang, Zhong, Sharova, Lioudmila, Sharov, Alexei A., Ling, Chen, Piao, Yulan, Aiba, Kazuhiro, Matoba, Ryo, Wang, Weidong, Ko, Minoru S. H.
Format:	Journal Article
Language:	English
Published:	Bristol John Wiley & Sons, Ltd 01.05.2008
Subjects:	Animals ARID1B BAF250B Biomarkers - metabolism Cell Cycle Cell Differentiation Cell Proliferation Chromatin Assembly and Disassembly Chromatin remodeling Chromosomal Proteins, Non-Histone - metabolism DNA microarray DNA-Binding Proteins - metabolism Down-Regulation Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Gene Expression Profiling Gene targeting HeLa Cells Humans Mice Pluripotent Stem Cells - cytology SWI/SNF Transcription Factors - genetics Transcription Factors - metabolism Up-Regulation
ISSN:	1066-5099, 1549-4918, 1549-4918
Online Access:	Get full text
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