The consequences of pain in early life: injury-induced plasticity in developing pain pathways

Pain in infancy influences pain reactivity in later life, but how and why this occurs is poorly understood. Here we review the evidence for developmental plasticity of nociceptive pathways in animal models and discuss the peripheral and central mechanisms that underlie this plasticity. Adults who ha...

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Bibliographic Details
Published in:	The European journal of neuroscience Vol. 39; no. 3; pp. 344 - 352
Main Authors:	Schwaller, Fred, Fitzgerald, Maria
Format:	Journal Article
Language:	English
Published:	France Blackwell Publishing Ltd 01.02.2014 BlackWell Publishing Ltd
Subjects:	Animal models Animals cannabinoids descending pain control Endocannabinoids - metabolism experience dependent-plasticity Humans hyperalgesia Hyperalgesia - metabolism Hyperalgesia - physiopathology Nervous System - growth & development Nervous System - metabolism Nervous System - physiopathology Neuralgia - metabolism Neuralgia - physiopathology Neuronal Plasticity newborn infant Special Issue: Neurobiology of Pain Trauma, Nervous System - metabolism Trauma, Nervous System - physiopathology experience dependent-plasticity cannabinoids hyperalgesia descending pain control newborn infant
ISSN:	0953-816X, 1460-9568, 1460-9568
Online Access:	Get full text
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