Different gDNA content in the subpopulations of prostate cancer extracellular vesicles: Apoptotic bodies, microvesicles, and exosomes

BACKGROUND Extracellular vesicles (EVs) are cell‐derived membrane vesicles. EVs contain several RNAs such as mRNA, microRNAs, and ncRNAs, but less is known of their genomic DNA (gDNA) content. It is also unknown whether the DNA cargo is randomly sorted or if it is systematically packed into specific...

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Bibliographic Details
Published in:	The Prostate Vol. 74; no. 14; pp. 1379 - 1390
Main Authors:	Lázaro-Ibáñez, Elisa, Sanz-Garcia, Andres, Visakorpi, Tapio, Escobedo-Lucea, Carmen, Siljander, Pia, Ayuso-Sacido, Ángel, Yliperttula, Marjo
Format:	Journal Article
Language:	English
Published:	United States Blackwell Publishing Ltd 01.10.2014 Wiley Subscription Services, Inc BlackWell Publishing Ltd
Subjects:	Apoptosis - genetics Case-Control Studies Cell Line, Tumor DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Exosomes - genetics Exosomes - metabolism Genes, p53 Humans Male Original Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology PTEN Phosphohydrolase - genetics
ISSN:	0270-4137, 1097-0045, 1097-0045
Online Access:	Get full text
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