Definition of an adapted cut-off for determining low lean tissue mass in older women with obesity: a comparison to current cut-offs

The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lea...

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Published in:Scientific reports Vol. 12; no. 1; pp. 16905 - 12
Main Authors: Maïmoun, Laurent, Serrand, Chris, Mura, Thibault, Renard, Eric, Nocca, David, Lefebvre, Patrick, Boudousq, Vincent, Avignon, Antoine, Mariano-Goulart, Denis, Sultan, Ariane
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 07.10.2022
Nature Publishing Group
Nature Portfolio
Subjects:
692/163
692/699
Absorptiometry, Photon
Aged
Body Composition
Body Mass Index
Endocrinology and metabolism
Female
Human health and pathology
Humanities and Social Sciences
Humans
Life Sciences
multidisciplinary
Obesity
Obesity / complications
Obesity / epidemiology
Santé publique et épidémiologie
Sarcopenia
Sarcopenia / diagnosis
Sarcopenia / epidemiology
Science
Science (multidisciplinary)
Tissues and Organs
ISSN:2045-2322, 2045-2322
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Abstract The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height 2 : ALMI(h 2 )] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h 2 ) < 5.5 kg/m 2 ; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h 2 ) < 5.67 kg/m 2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h 2 ) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h 2 ) < 7.15 kg/m 2 , ALMI(BMI) < 0.483, and T-score: [(ALMI(h 2 ) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h 2 ) that took into account the BMI and thus the obesity severity appeared even more relevant.
AbstractList The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height 2: ALMI(h 2 )] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h 2 ) < 5.5 kg/m 2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h 2 ) < 5.67 kg/m 2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h 2 ) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h 2 ) < 7.15 kg/m 2 , ALMI(BMI) < 0.483, and T-score: [(ALMI(h 2 ) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h 2 ) that took into account the BMI and thus the obesity severity appeared even more relevant.
The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height 2 : ALMI(h 2 )] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h 2 ) < 5.5 kg/m 2 ; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h 2 ) < 5.67 kg/m 2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h 2 ) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h 2 ) < 7.15 kg/m 2 , ALMI(BMI) < 0.483, and T-score: [(ALMI(h 2 ) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h 2 ) that took into account the BMI and thus the obesity severity appeared even more relevant.
The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height2: ALMI(h2)] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h2) < 5.5 kg/m2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h2) < 5.67 kg/m2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h2) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h2) < 7.15 kg/m2, ALMI(BMI) < 0.483, and T-score: [(ALMI(h2) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h2) that took into account the BMI and thus the obesity severity appeared even more relevant.
Abstract The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height2: ALMI(h2)] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h2) < 5.5 kg/m2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h2) < 5.67 kg/m2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h2) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h2) < 7.15 kg/m2, ALMI(BMI) < 0.483, and T-score: [(ALMI(h2) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h2) that took into account the BMI and thus the obesity severity appeared even more relevant.
The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height2: ALMI(h2)] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h2) < 5.5 kg/m2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h2) < 5.67 kg/m2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h2) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied – i.e., ALM < 18.51 kg; ALMI(h2) < 7.15 kg/m2, ALMI(BMI) < 0.483, and T-score: [(ALMI(h2) measured)-(2.08 + 0.183*BMI)]/0.72] − the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new “static” cut-offs appeared to be more adapted, a “dynamic” cut-off for ALMI(h2) that took into account the BMI and thus the obesity severity appeared even more relevant.
The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height2: ALMI(h2)] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h2) < 5.5 kg/m2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h2) < 5.67 kg/m2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h2) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied - i.e., ALM < 18.51 kg; ALMI(h2) < 7.15 kg/m2, ALMI(BMI) < 0.483, and T-score: [(ALMI(h2) measured)-(2.08 + 0.183*BMI)]/0.72] - the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new "static" cut-offs appeared to be more adapted, a "dynamic" cut-off for ALMI(h2) that took into account the BMI and thus the obesity severity appeared even more relevant.The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of sarcopenia in terms of lean tissue mass in older women with obesity using the current cut-offs, (ii) redefine a specific cut-off for low lean tissue mass (LLTM), and (iii) re-determine the prevalence of LLTM using this new cut-off. Appendicular lean mass (ALM) and the ALM index [ALM/height2: ALMI(h2)] and ALMI/body mass index [ALMI(BMI)] were determined in 791 women with or without obesity. LLMM prevalence was calculated using the current cut-offs: EWGSOP2: ALM < 15 kg and ALMI(h2) < 5.5 kg/m2; FNIH: ALM < 15.02 kg and ALMI(BMI) < 0.51; and IWGS: ALMI(h2) < 5.67 kg/m2 and cut-offs newly determined from data provided from young women with obesity. ALM, ALMI(h2) and ALMI(BMI) were lower in older compared to young obese women. Using the current cut-offs, a wide distribution of LLTM prevalence (0 to 29.2%) was observed. When the newly determined cut-offs were applied - i.e., ALM < 18.51 kg; ALMI(h2) < 7.15 kg/m2, ALMI(BMI) < 0.483, and T-score: [(ALMI(h2) measured)-(2.08 + 0.183*BMI)]/0.72] - the LLTM mass prevalence was 17.37%; 8.47, 14.8 and 12.71%. respectively. This study showed that the current cut-offs for LLTM as criteria for sarcopenia diagnosis are not adapted to the obese population. Although the new "static" cut-offs appeared to be more adapted, a "dynamic" cut-off for ALMI(h2) that took into account the BMI and thus the obesity severity appeared even more relevant.
ArticleNumber 16905
Author Serrand, Chris
Nocca, David
Lefebvre, Patrick
Mariano-Goulart, Denis
Mura, Thibault
Avignon, Antoine
Boudousq, Vincent
Maïmoun, Laurent
Sultan, Ariane
Renard, Eric
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Cites_doi 10.1093/ageing/afq034
10.1080/13685538.2018.1511976
10.1038/sj.ejcn.1601198
10.1093/ajcn/64.3.472S
10.1007/s00198-015-3194-y[pii]
10.1038/oby.2004.250
10.1093/gerona/glu012
10.1007/s13539-011-0036-4
10.1016/j.clnu.2021.06.009
10.1111/ggi.12720
10.1093/ajcn/52.2.214
10.1111/jgs.12260
10.1016/j.clnu.2021.04.002
10.1016/j.bone.2015.11.020
10.1186/s40200-017-0302-x
10.1093/gerona/glu010
10.1016/S2213-8587(19)30158-5
10.1016/j.ehb.2007.02.002
10.1007/s00198-017-3964-9
10.1093/ageing/afz046
10.1007/s12603-014-0561-x
10.1016/S0140-6736(19)30955-9
10.1152/jappl.2000.89.1.81
10.1016/j.clnu.2007.10.008
10.1093/ageing/afs194
10.1093/gerona/61.10.1059
10.1016/j.jamda.2013.02.010
10.1016/j.jamda.2011.01.003
10.1093/gerona/57.12.M772
10.3390/ijerph13080821
10.1067/mlc.2001.113504
10.1016/j.soard.2017.01.017
10.1007/s12603-011-0088-3
10.1038/ejcn.2014.117
10.1159/000377699
10.1016/j.arr.2016.09.008
10.1152/japplphysiol.00315.2019
10.1093/gerona/glt131
10.1016/j.clnu.2021.11.014
10.1016/j.numecd.2007.10.002
10.1093/gerona/50A.6.M307
10.1111/j.1532-5415.2007.01140.x
10.1046/j.1532-5415.2003.51534.x
10.1093/oxfordjournals.aje.a009520
10.3904/kjim.2016.015
10.11005/jbm.2015.22.2.71
10.1088/1361-6579/ab8e5f
10.3390/jcm9041188
10.1038/sj.ijo.0802552
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References Baumgartner, Stauber, McHugh, Koehler, Garry (CR1) 1995; 50
Batsis, Villareal (CR19) 2018; 14
Cruz-Jentoft (CR8) 2019; 48
McLean (CR28) 2014; 69
Zoico (CR43) 2004; 28
Wen, Wang, Jiang, Zhang (CR27) 2011; 15
Batsis, Mackenzie, Barre, Lopez-Jimenez, Bartels (CR13) 2014; 68
Maimoun, Mura, Avignon, Mariano-Goulart, Sultan (CR18) 2020; 9
Gao (CR44) 2021; 40
Zamboni, Mazzali, Fantin, Rossi, Di Francesco (CR15) 2008; 18
Janssen, Heymsfield, Wang, Ross (CR2) 2000; 1985
Bahat, Kilic, Ozkok, Ozturk, Karan (CR42) 2021; 40
Landi (CR6) 2013; 42
Newman (CR34) 2003; 51
Heymsfield (CR24) 1990; 52
Diz (CR37) 2017; 17
Ray (CR21) 2019; 7
Kyle (CR3) 2001; 55
Shafiee (CR33) 2017; 16
Kemmler (CR51) 2017; 28
Bischoff-Ferrari (CR7) 2015; 26
Maimoun (CR46) 2016; 90
Batsis (CR14) 2013; 61
Cruz-Jentoft (CR5) 2010; 39
Goodpaster (CR47) 2006; 61
Donini (CR9) 2022; 41
Tian, Morio, Denis, Mioche (CR17) 2016
Baumgartner (CR12) 2004; 12
Kim, Jang, Lim (CR45) 2016; 31
Coin (CR30) 2013; 14
Scott, Blizzard, Fell, Jones (CR35) 2011; 2
Studenski (CR16) 2014; 69
Park (CR39) 2020
Baumgartner (CR25) 1998; 147
Morley, Baumgartner, Roubenoff, Mayer, Nair (CR41) 2001; 137
Garcia, Quintana-Domeque (CR31) 2007; 5
Maimoun (CR23) 2017; 13
Coin (CR4) 2008; 27
Bahat, Tufan, Kilic, Karan, Cruz-Jentoft (CR48) 2020; 23
Delmonico (CR50) 2007; 55
Fielding (CR29) 2011; 12
Iannuzzi-Sucich, Prestwood, Kenny (CR40) 2002; 57
Reijnierse (CR38) 2015; 61
CR20
Murphy (CR49) 2014; 69
Gonzalez-Correa, Marulanda Mejia, Castano Gonzalez, Vidarte Claros, Castiblanco Arroyabe (CR36) 2020
Geldsetzer (CR22) 2019; 394
Kwon, Ha, Park (CR26) 2015; 22
Heber (CR10) 1996; 64
Wen, An, Chen, Lv, Fu (CR32) 2015; 19
Kalinkovich, Livshits (CR11) 2017; 35
HA Bischoff-Ferrari (21258_CR7) 2015; 26
J Garcia (21258_CR31) 2007; 5
JE Morley (21258_CR41) 2001; 137
RN Baumgartner (21258_CR25) 1998; 147
AB Newman (21258_CR34) 2003; 51
AJ Cruz-Jentoft (21258_CR5) 2010; 39
A Coin (21258_CR30) 2013; 14
F Landi (21258_CR6) 2013; 42
KK Ray (21258_CR21) 2019; 7
L Maimoun (21258_CR23) 2017; 13
CH Gonzalez-Correa (21258_CR36) 2020
JA Batsis (21258_CR19) 2018; 14
M Iannuzzi-Sucich (21258_CR40) 2002; 57
HJ Kwon (21258_CR26) 2015; 22
YM Park (21258_CR39) 2020
EM Reijnierse (21258_CR38) 2015; 61
G Bahat (21258_CR48) 2020; 23
SB Heymsfield (21258_CR24) 1990; 52
W Kemmler (21258_CR51) 2017; 28
X Wen (21258_CR32) 2015; 19
MJ Delmonico (21258_CR50) 2007; 55
G Shafiee (21258_CR33) 2017; 16
D Scott (21258_CR35) 2011; 2
I Janssen (21258_CR2) 2000; 1985
D Heber (21258_CR10) 1996; 64
AJ Cruz-Jentoft (21258_CR8) 2019; 48
SA Studenski (21258_CR16) 2014; 69
RN Baumgartner (21258_CR12) 2004; 12
UG Kyle (21258_CR3) 2001; 55
KM Kim (21258_CR45) 2016; 31
G Bahat (21258_CR42) 2021; 40
L Maimoun (21258_CR46) 2016; 90
X Wen (21258_CR27) 2011; 15
A Coin (21258_CR4) 2008; 27
21258_CR20
JA Batsis (21258_CR13) 2014; 68
JA Batsis (21258_CR14) 2013; 61
LM Donini (21258_CR9) 2022; 41
M Zamboni (21258_CR15) 2008; 18
JB Diz (21258_CR37) 2017; 17
Q Gao (21258_CR44) 2021; 40
RA Fielding (21258_CR29) 2011; 12
L Maimoun (21258_CR18) 2020; 9
P Geldsetzer (21258_CR22) 2019; 394
BH Goodpaster (21258_CR47) 2006; 61
RN Baumgartner (21258_CR1) 1995; 50
E Zoico (21258_CR43) 2004; 28
RR McLean (21258_CR28) 2014; 69
A Kalinkovich (21258_CR11) 2017; 35
S Tian (21258_CR17) 2016
RA Murphy (21258_CR49) 2014; 69
References_xml – volume: 39
  start-page: 412
  year: 2010
  end-page: 423
  ident: CR5
  article-title: Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People
  publication-title: Age Ageing
  doi: 10.1093/ageing/afq034
– volume: 23
  start-page: 424
  year: 2020
  end-page: 430
  ident: CR48
  article-title: Prevalence of sarcopenia and its components in community-dwelling outpatient older adults and their relation with functionality
  publication-title: Aging Male
  doi: 10.1080/13685538.2018.1511976
– volume: 55
  start-page: 663
  year: 2001
  end-page: 672
  ident: CR3
  article-title: Age-related differences in fat-free mass, skeletal muscle, body cell mass and fat mass between 18 and 94 years
  publication-title: Eur. J. Clin. Nutr.
  doi: 10.1038/sj.ejcn.1601198
– volume: 64
  start-page: 472S
  year: 1996
  end-page: 477S
  ident: CR10
  article-title: Clinical detection of sarcopenic obesity by bioelectrical impedance analysis
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/64.3.472S
– volume: 26
  start-page: 2793
  year: 2015
  end-page: 2802
  ident: CR7
  article-title: Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older
  publication-title: Osteoporos. Int.
  doi: 10.1007/s00198-015-3194-y[pii]
– volume: 12
  start-page: 1995
  year: 2004
  end-page: 2004
  ident: CR12
  article-title: Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly
  publication-title: Obes. Res.
  doi: 10.1038/oby.2004.250
– volume: 69
  start-page: 576
  year: 2014
  end-page: 583
  ident: CR28
  article-title: Criteria for clinically relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: the foundation for the National Institutes of Health (FNIH) sarcopenia project
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glu012
– volume: 2
  start-page: 125
  year: 2011
  end-page: 134
  ident: CR35
  article-title: The epidemiology of sarcopenia in community living older adults: What role does lifestyle play?
  publication-title: J. Cachexia Sarcopenia Muscle
  doi: 10.1007/s13539-011-0036-4
– volume: 40
  start-page: 4633
  year: 2021
  end-page: 4641
  ident: CR44
  article-title: Global prevalence of sarcopenic obesity in older adults: A systematic review and meta-analysis
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.06.009
– volume: 14
  start-page: 513
  year: 2018
  end-page: 537
  ident: CR19
  article-title: Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies
  publication-title: Nat. Rev.
– volume: 17
  start-page: 5
  year: 2017
  end-page: 16
  ident: CR37
  article-title: Prevalence of sarcopenia in older Brazilians: A systematic review and meta-analysis
  publication-title: Geriatr. Gerontol. Int.
  doi: 10.1111/ggi.12720
– volume: 52
  start-page: 214
  year: 1990
  end-page: 218
  ident: CR24
  article-title: Appendicular skeletal muscle mass: Measurement by dual-photon absorptiometry
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/52.2.214
– volume: 61
  start-page: 974
  year: 2013
  end-page: 980
  ident: CR14
  article-title: Variation in the prevalence of sarcopenia and sarcopenic obesity in older adults associated with differente research definitions: dual-energy X-ray absorptiometry data from the National health and nutrition examination survery: 1999–2004
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1111/jgs.12260
– volume: 40
  start-page: 2851
  year: 2021
  end-page: 2859
  ident: CR42
  article-title: Associations of sarcopenic obesity versus sarcopenia alone with functionality
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.04.002
– volume: 90
  start-page: 23
  year: 2016
  end-page: 30
  ident: CR46
  article-title: Impact of obesity on bone mass throughout adult life: Influence of gender and severity of obesity
  publication-title: Bone
  doi: 10.1016/j.bone.2015.11.020
– volume: 16
  start-page: 21
  year: 2017
  ident: CR33
  article-title: Prevalence of sarcopenia in the world: A systematic review and meta- analysis of general population studies
  publication-title: J. Diabetes Metab. Disord.
  doi: 10.1186/s40200-017-0302-x
– volume: 69
  start-page: 547
  year: 2014
  end-page: 558
  ident: CR16
  article-title: The FNIH sarcopenia project: Rationale, study description, conference recommendations, and final estimates
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glu010
– volume: 7
  start-page: 618
  year: 2019
  end-page: 628
  ident: CR21
  article-title: Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: A prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial
  publication-title: Lancet Diabetes Endocrinol.
  doi: 10.1016/S2213-8587(19)30158-5
– volume: 5
  start-page: 340
  year: 2007
  end-page: 349
  ident: CR31
  article-title: The evolution of adult height in Europe: A brief note
  publication-title: Econ. Hum. Biol.
  doi: 10.1016/j.ehb.2007.02.002
– volume: 28
  start-page: 1881
  year: 2017
  end-page: 1891
  ident: CR51
  article-title: Prevalence of sarcopenia and sarcopenic obesity in older German men using recognized definitions: High accordance but low overlap!
  publication-title: Osteoporos. Int.
  doi: 10.1007/s00198-017-3964-9
– volume: 48
  start-page: 601
  year: 2019
  ident: CR8
  article-title: Sarcopenia: Revised European consensus on definition and diagnosis
  publication-title: Age Ageing
  doi: 10.1093/ageing/afz046
– volume: 19
  start-page: 342
  year: 2015
  end-page: 347
  ident: CR32
  article-title: Comparisons of sarcopenia prevalence based on different diagnostic criteria in Chinese older adults
  publication-title: J. Nutr. Health Aging
  doi: 10.1007/s12603-014-0561-x
– volume: 394
  start-page: 652
  year: 2019
  end-page: 662
  ident: CR22
  article-title: The state of hypertension care in 44 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level data from 1.1 million adults
  publication-title: Lancet
  doi: 10.1016/S0140-6736(19)30955-9
– volume: 1985
  start-page: 81
  issue: 89
  year: 2000
  end-page: 88
  ident: CR2
  article-title: Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr
  publication-title: J. Appl. Physiol.
  doi: 10.1152/jappl.2000.89.1.81
– volume: 27
  start-page: 87
  year: 2008
  end-page: 94
  ident: CR4
  article-title: Fat-free mass and fat mass reference values by dual-energy X-ray absorptiometry (DEXA) in a 20–80 year-old Italian population
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2007.10.008
– volume: 42
  start-page: 203
  year: 2013
  end-page: 209
  ident: CR6
  article-title: Sarcopenia and mortality risk in frail older persons aged 80 years and older: Results from ilSIRENTE study
  publication-title: Age Ageing
  doi: 10.1093/ageing/afs194
– volume: 61
  start-page: 1059
  year: 2006
  end-page: 1064
  ident: CR47
  article-title: The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/61.10.1059
– volume: 14
  start-page: 507
  year: 2013
  end-page: 512
  ident: CR30
  article-title: Prevalence of sarcopenia based on different diagnostic criteria using DEXA and appendicular skeletal muscle mass reference values in an Italian population aged 20 to 80
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2013.02.010
– volume: 12
  start-page: 249
  year: 2011
  end-page: 256
  ident: CR29
  article-title: Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2011.01.003
– volume: 57
  start-page: M772
  year: 2002
  end-page: 777
  ident: CR40
  article-title: Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/57.12.M772
– year: 2016
  ident: CR17
  article-title: Age-related changes in segmental body composition by ethnicity and history of weight change across the adult lifespan
  publication-title: Int. J. Environ. Res. Public Health
  doi: 10.3390/ijerph13080821
– volume: 137
  start-page: 231
  year: 2001
  end-page: 243
  ident: CR41
  article-title: Sarcopenia
  publication-title: J. Lab. Clin. Med.
  doi: 10.1067/mlc.2001.113504
– volume: 13
  start-page: 780
  year: 2017
  end-page: 787
  ident: CR23
  article-title: Body composition changes in the first month after sleeve gastrectomy based on gender and anatomic site
  publication-title: Surg. Obes. Relat. Dis.
  doi: 10.1016/j.soard.2017.01.017
– volume: 15
  start-page: 847
  year: 2011
  end-page: 851
  ident: CR27
  article-title: Are current definitions of sarcopenia applicable for older Chinese adults?
  publication-title: J. Nutr. Health Aging
  doi: 10.1007/s12603-011-0088-3
– volume: 68
  start-page: 1001
  year: 2014
  end-page: 1007
  ident: CR13
  article-title: Sarcopenia, sarcopenic obesity and mortality in older adults: Results from the National Health and Nutrition examination survey III
  publication-title: Eur. J. Clin. Nutr.
  doi: 10.1038/ejcn.2014.117
– volume: 61
  start-page: 491
  year: 2015
  end-page: 496
  ident: CR38
  article-title: The impact of different diagnostic criteria on the prevalence of sarcopenia in healthy elderly participants and geriatric outpatients
  publication-title: Gerontology
  doi: 10.1159/000377699
– volume: 35
  start-page: 200
  year: 2017
  end-page: 221
  ident: CR11
  article-title: Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesis
  publication-title: Ageing Res. Rev.
  doi: 10.1016/j.arr.2016.09.008
– year: 2020
  ident: CR39
  article-title: Appendicular lean mass is lower in late- compared to early- perimenopausal women: Potential role of FSH
  publication-title: J. Appl. Physiol.
  doi: 10.1152/japplphysiol.00315.2019
– volume: 69
  start-page: 751
  year: 2014
  end-page: 758
  ident: CR49
  article-title: Transition to sarcopenia and determinants of transitions in older adults: A population-based study
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glt131
– volume: 41
  start-page: 990
  year: 2022
  end-page: 1000
  ident: CR9
  article-title: Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.11.014
– volume: 18
  start-page: 388
  year: 2008
  end-page: 395
  ident: CR15
  article-title: Sarcopenic obesity: A new category of obesity in the elderly
  publication-title: Nutr. Metab. Cardiovasc. Dis.
  doi: 10.1016/j.numecd.2007.10.002
– volume: 50
  start-page: M307
  year: 1995
  end-page: 316
  ident: CR1
  article-title: Cross-sectional age differences in body composition in persons 60+ years of age
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/50A.6.M307
– volume: 55
  start-page: 769
  year: 2007
  end-page: 774
  ident: CR50
  article-title: Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1111/j.1532-5415.2007.01140.x
– volume: 51
  start-page: 1602
  year: 2003
  end-page: 1609
  ident: CR34
  article-title: Sarcopenia: Alternative definitions and associations with lower extremity function
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1046/j.1532-5415.2003.51534.x
– volume: 147
  start-page: 755
  year: 1998
  end-page: 763
  ident: CR25
  article-title: Epidemiology of sarcopenia among the elderly in New Mexico
  publication-title: Am. J. Epidemiol.
  doi: 10.1093/oxfordjournals.aje.a009520
– volume: 31
  start-page: 643
  year: 2016
  end-page: 650
  ident: CR45
  article-title: Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia
  publication-title: Korean J. Int. Med.
  doi: 10.3904/kjim.2016.015
– volume: 22
  start-page: 71
  year: 2015
  end-page: 75
  ident: CR26
  article-title: The reference value of skeletal muscle mass index for defining the sarcopenia of women in Korea
  publication-title: J. Bone Metab.
  doi: 10.11005/jbm.2015.22.2.71
– year: 2020
  ident: CR36
  article-title: Bioelectrical impedance analysis and dual X-ray absorptiometry agreement for skeletal muscle mass index evaluation in sarcopenia diagnosis
  publication-title: Physiol. Meas.
  doi: 10.1088/1361-6579/ab8e5f
– volume: 9
  start-page: 1188
  year: 2020
  ident: CR18
  article-title: Body composition in individuals with obesity according to age and sex: A cross-sectional study
  publication-title: J Clin Med
  doi: 10.3390/jcm9041188
– ident: CR20
– volume: 28
  start-page: 234
  year: 2004
  end-page: 241
  ident: CR43
  article-title: Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women
  publication-title: Int. J. Obes. Relat. Metab. Disord.
  doi: 10.1038/sj.ijo.0802552
– year: 2016
  ident: 21258_CR17
  publication-title: Int. J. Environ. Res. Public Health
  doi: 10.3390/ijerph13080821
– volume: 14
  start-page: 507
  year: 2013
  ident: 21258_CR30
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2013.02.010
– volume: 137
  start-page: 231
  year: 2001
  ident: 21258_CR41
  publication-title: J. Lab. Clin. Med.
  doi: 10.1067/mlc.2001.113504
– volume: 64
  start-page: 472S
  year: 1996
  ident: 21258_CR10
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/64.3.472S
– volume: 17
  start-page: 5
  year: 2017
  ident: 21258_CR37
  publication-title: Geriatr. Gerontol. Int.
  doi: 10.1111/ggi.12720
– volume: 28
  start-page: 234
  year: 2004
  ident: 21258_CR43
  publication-title: Int. J. Obes. Relat. Metab. Disord.
  doi: 10.1038/sj.ijo.0802552
– volume: 69
  start-page: 751
  year: 2014
  ident: 21258_CR49
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glt131
– volume: 12
  start-page: 1995
  year: 2004
  ident: 21258_CR12
  publication-title: Obes. Res.
  doi: 10.1038/oby.2004.250
– volume: 1985
  start-page: 81
  issue: 89
  year: 2000
  ident: 21258_CR2
  publication-title: J. Appl. Physiol.
  doi: 10.1152/jappl.2000.89.1.81
– volume: 61
  start-page: 491
  year: 2015
  ident: 21258_CR38
  publication-title: Gerontology
  doi: 10.1159/000377699
– volume: 18
  start-page: 388
  year: 2008
  ident: 21258_CR15
  publication-title: Nutr. Metab. Cardiovasc. Dis.
  doi: 10.1016/j.numecd.2007.10.002
– volume: 27
  start-page: 87
  year: 2008
  ident: 21258_CR4
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2007.10.008
– volume: 55
  start-page: 769
  year: 2007
  ident: 21258_CR50
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1111/j.1532-5415.2007.01140.x
– volume: 61
  start-page: 1059
  year: 2006
  ident: 21258_CR47
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/61.10.1059
– volume: 55
  start-page: 663
  year: 2001
  ident: 21258_CR3
  publication-title: Eur. J. Clin. Nutr.
  doi: 10.1038/sj.ejcn.1601198
– volume: 39
  start-page: 412
  year: 2010
  ident: 21258_CR5
  publication-title: Age Ageing
  doi: 10.1093/ageing/afq034
– volume: 51
  start-page: 1602
  year: 2003
  ident: 21258_CR34
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1046/j.1532-5415.2003.51534.x
– volume: 22
  start-page: 71
  year: 2015
  ident: 21258_CR26
  publication-title: J. Bone Metab.
  doi: 10.11005/jbm.2015.22.2.71
– volume: 52
  start-page: 214
  year: 1990
  ident: 21258_CR24
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/52.2.214
– volume: 61
  start-page: 974
  year: 2013
  ident: 21258_CR14
  publication-title: J. Am. Geriatr. Soc.
  doi: 10.1111/jgs.12260
– volume: 23
  start-page: 424
  year: 2020
  ident: 21258_CR48
  publication-title: Aging Male
  doi: 10.1080/13685538.2018.1511976
– volume: 42
  start-page: 203
  year: 2013
  ident: 21258_CR6
  publication-title: Age Ageing
  doi: 10.1093/ageing/afs194
– volume: 40
  start-page: 4633
  year: 2021
  ident: 21258_CR44
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.06.009
– volume: 26
  start-page: 2793
  year: 2015
  ident: 21258_CR7
  publication-title: Osteoporos. Int.
  doi: 10.1007/s00198-015-3194-y[pii]
– volume: 9
  start-page: 1188
  year: 2020
  ident: 21258_CR18
  publication-title: J Clin Med
  doi: 10.3390/jcm9041188
– ident: 21258_CR20
– year: 2020
  ident: 21258_CR36
  publication-title: Physiol. Meas.
  doi: 10.1088/1361-6579/ab8e5f
– volume: 69
  start-page: 547
  year: 2014
  ident: 21258_CR16
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glu010
– volume: 5
  start-page: 340
  year: 2007
  ident: 21258_CR31
  publication-title: Econ. Hum. Biol.
  doi: 10.1016/j.ehb.2007.02.002
– year: 2020
  ident: 21258_CR39
  publication-title: J. Appl. Physiol.
  doi: 10.1152/japplphysiol.00315.2019
– volume: 28
  start-page: 1881
  year: 2017
  ident: 21258_CR51
  publication-title: Osteoporos. Int.
  doi: 10.1007/s00198-017-3964-9
– volume: 147
  start-page: 755
  year: 1998
  ident: 21258_CR25
  publication-title: Am. J. Epidemiol.
  doi: 10.1093/oxfordjournals.aje.a009520
– volume: 41
  start-page: 990
  year: 2022
  ident: 21258_CR9
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.11.014
– volume: 40
  start-page: 2851
  year: 2021
  ident: 21258_CR42
  publication-title: Clin. Nutr.
  doi: 10.1016/j.clnu.2021.04.002
– volume: 57
  start-page: M772
  year: 2002
  ident: 21258_CR40
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/57.12.M772
– volume: 7
  start-page: 618
  year: 2019
  ident: 21258_CR21
  publication-title: Lancet Diabetes Endocrinol.
  doi: 10.1016/S2213-8587(19)30158-5
– volume: 12
  start-page: 249
  year: 2011
  ident: 21258_CR29
  publication-title: J. Am. Med. Dir. Assoc.
  doi: 10.1016/j.jamda.2011.01.003
– volume: 14
  start-page: 513
  year: 2018
  ident: 21258_CR19
  publication-title: Nat. Rev.
– volume: 35
  start-page: 200
  year: 2017
  ident: 21258_CR11
  publication-title: Ageing Res. Rev.
  doi: 10.1016/j.arr.2016.09.008
– volume: 2
  start-page: 125
  year: 2011
  ident: 21258_CR35
  publication-title: J. Cachexia Sarcopenia Muscle
  doi: 10.1007/s13539-011-0036-4
– volume: 394
  start-page: 652
  year: 2019
  ident: 21258_CR22
  publication-title: Lancet
  doi: 10.1016/S0140-6736(19)30955-9
– volume: 68
  start-page: 1001
  year: 2014
  ident: 21258_CR13
  publication-title: Eur. J. Clin. Nutr.
  doi: 10.1038/ejcn.2014.117
– volume: 13
  start-page: 780
  year: 2017
  ident: 21258_CR23
  publication-title: Surg. Obes. Relat. Dis.
  doi: 10.1016/j.soard.2017.01.017
– volume: 90
  start-page: 23
  year: 2016
  ident: 21258_CR46
  publication-title: Bone
  doi: 10.1016/j.bone.2015.11.020
– volume: 69
  start-page: 576
  year: 2014
  ident: 21258_CR28
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/glu012
– volume: 15
  start-page: 847
  year: 2011
  ident: 21258_CR27
  publication-title: J. Nutr. Health Aging
  doi: 10.1007/s12603-011-0088-3
– volume: 19
  start-page: 342
  year: 2015
  ident: 21258_CR32
  publication-title: J. Nutr. Health Aging
  doi: 10.1007/s12603-014-0561-x
– volume: 50
  start-page: M307
  year: 1995
  ident: 21258_CR1
  publication-title: J. Gerontol. A Biol. Sci. Med. Sci.
  doi: 10.1093/gerona/50A.6.M307
– volume: 16
  start-page: 21
  year: 2017
  ident: 21258_CR33
  publication-title: J. Diabetes Metab. Disord.
  doi: 10.1186/s40200-017-0302-x
– volume: 31
  start-page: 643
  year: 2016
  ident: 21258_CR45
  publication-title: Korean J. Int. Med.
  doi: 10.3904/kjim.2016.015
– volume: 48
  start-page: 601
  year: 2019
  ident: 21258_CR8
  publication-title: Age Ageing
  doi: 10.1093/ageing/afz046
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Snippet The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the prevalence of...
Abstract The prevalence of sarcopenia in patients with obesity varies according to the definition used. The purpose of our study was to: (i) determine the...
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StartPage 16905
SubjectTerms 692/163
692/699
Absorptiometry, Photon
Aged
Body Composition
Body Mass Index
Endocrinology and metabolism
Female
Human health and pathology
Humanities and Social Sciences
Humans
Life Sciences
multidisciplinary
Obesity
Obesity / complications
Obesity / epidemiology
Santé publique et épidémiologie
Sarcopenia
Sarcopenia / diagnosis
Sarcopenia / epidemiology
Science
Science (multidisciplinary)
Tissues and Organs
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Title Definition of an adapted cut-off for determining low lean tissue mass in older women with obesity: a comparison to current cut-offs
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