Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

Motivation: The recently released Infinium HumanMethylation450 array (the ‘450k’ array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features. Although less comprehensive than high-throughput sequencing-based techniques, this product...

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Veröffentlicht in:	Bioinformatics Jg. 30; H. 10; S. 1363 - 1369
Hauptverfasser:	Aryee, Martin J., Jaffe, Andrew E., Corrada-Bravo, Hector, Ladd-Acosta, Christine, Feinberg, Andrew P., Hansen, Kasper D., Irizarry, Rafael A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 15.05.2014
Schlagworte:	Aged Algorithms Colonic Neoplasms - genetics DNA Methylation Genome High-Throughput Nucleotide Sequencing - methods Humans Oligonucleotide Array Sequence Analysis - methods Original Papers Polymorphism, Single Nucleotide Software
ISSN:	1367-4803, 1367-4811, 1460-2059, 1367-4811
Online-Zugang:	Volltext
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