BiPOm: a rule-based ontology to represent and infer molecule knowledge from a biological process-centered viewpoint

Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system compose...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	BMC bioinformatics Ročník 21; číslo 1; s. 1 - 18
Hlavní autori:	Henry, Vincent, Saïs, Fatiha, Inizan, Olivier, Marchadier, Elodie, Dibie, Juliette, Goelzer, Anne, Fromion, Vincent
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 23.07.2020 Springer Nature B.V BMC
Predmet:	Algorithms Bioinformatics Biological activity Biomedical and Life Sciences Cognition & reasoning Computational Biology/Bioinformatics Computer Appl. in Life Sciences Computer Science Cultural heritage Formal Languages and Automata Theory Knowledge Knowledge management Knowledge representation Knowledge-based analysis Life Sciences Logical rules Metabolic processes Metabolism Methodology Methodology Article Microarrays Molecular biology Ontology Semantic web Semantics Substrates Subsystems Web Ontology Language-OWL Ontology Logical rules Metabolic processes
ISSN:	1471-2105, 1471-2105
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Abstract	Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes. Results We introduce BiPOm ( B iological i nterlocked P rocess O ntology for m etabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies. Conclusion BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process. Availability BiPOm can be downloaded at https://github.com/SysBioInra/SysOnto
AbstractList	Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes. Results We introduce BiPOm ( B iological i nterlocked P rocess O ntology for m etabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies. Conclusion BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process. Availability BiPOm can be downloaded at https://github.com/SysBioInra/SysOnto Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes.BACKGROUNDManaging and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes.We introduce BiPOm (Biological interlocked Process Ontology for metabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies.RESULTSWe introduce BiPOm (Biological interlocked Process Ontology for metabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies.BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process.CONCLUSIONBiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process.BiPOm can be downloaded at https://github.com/SysBioInra/SysOnto.AVAILABILITYBiPOm can be downloaded at https://github.com/SysBioInra/SysOnto. Background: Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes. Results: We introduce BiPOm (Biological interlocked Process Ontology for metabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies. Conclusion: BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process. Abstract Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes. Results We introduce BiPOm (Biological interlocked Process Ontology for metabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies. Conclusion BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process. Availability BiPOm can be downloaded at https://github.com/SysBioInra/SysOnto Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been promising in tackling such a challenge at the whole-cell scale. In such representations, the cell is considered as a system composed of interlocked subsystems. The need is now to define a relevant formalization of the systemic description of cellular processes. Results We introduce BiPOm (Biological interlocked Process Ontology for metabolism) an ontology to represent metabolic processes as interlocked subsystems using a limited number of classes and properties. We explicitly formalized the relations between the enzyme, its activity, the substrates and the products of the reaction, as well as the active state of all involved molecules. We further showed that the information of molecules such as molecular types or molecular properties can be deduced by automatic reasoning using logical rules. The information necessary to populate BiPOm can be extracted from existing databases or existing bio-ontologies. Conclusion BiPOm provides a formal rule-based knowledge representation to relate all cellular components together by considering the cellular system as a whole. It relies on a paradigm shift where the anchorage of knowledge is rerouted from the molecule to the biological process. Availability BiPOm can be downloaded at https://github.com/SysBioInra/SysOnto
ArticleNumber	327
Author	Saïs, Fatiha Goelzer, Anne Henry, Vincent Dibie, Juliette Fromion, Vincent Inizan, Olivier Marchadier, Elodie
Author_xml	– sequence: 1 givenname: Vincent surname: Henry fullname: Henry, Vincent organization: Université Paris-Saclay, INRAE, MaIAGE – sequence: 2 givenname: Fatiha surname: Saïs fullname: Saïs, Fatiha organization: LRI, UMR 8623, CNRS, Université Paris-Sud, Université Paris Saclay – sequence: 3 givenname: Olivier surname: Inizan fullname: Inizan, Olivier organization: Université Paris-Saclay, INRAE, MaIAGE – sequence: 4 givenname: Elodie surname: Marchadier fullname: Marchadier, Elodie organization: Université Paris-Saclay, INRAE, CNRS, AgroParisTech – sequence: 5 givenname: Juliette surname: Dibie fullname: Dibie, Juliette organization: UMR MIA-Paris, AgroParisTech, INRAE, Université Paris Saclay – sequence: 6 givenname: Anne orcidid: 0000-0003-2222-6142 surname: Goelzer fullname: Goelzer, Anne email: anne.goelzer@inrae.fr organization: Université Paris-Saclay, INRAE, MaIAGE – sequence: 7 givenname: Vincent surname: Fromion fullname: Fromion, Vincent organization: Université Paris-Saclay, INRAE, MaIAGE
BackLink	https://hal.science/hal-02907978$$DView record in HAL
BookMark	eNp9kk1v1DAQhiNURD_gD3CKxAUOgXHir3BAKhXQSiuVA5wtx5lsvTj2Yme36r_HaYqge-jJ1vh9Ho-tOS2OfPBYFK8JvCdE8g-J1JK1FdRQQcMbUbXPihNCBalqAuzov_1xcZrSBoAICexFcdzUAhrC4aRIn-336_Fjqcu4c1h1OmFfBj8FF9Z35RTKiNuICf1Uat-X1g8YyzE4NDle_vLh1mG_xnKIYcySzs6gNdqV2xgMplSZzGLM1r3F222wfnpZPB-0S_jqYT0rfn798uPislpdf7u6OF9VhjEyVU2HOBBoewlkqGk3dAwFaA6gCRo2EEk41dBr0wuORPaAPeVIhUBNBNXNWXG1ePugN2ob7ajjnQraqvtCiGul42SNQ4WiGTLRdpozOgitKaWSG8PMIGW2ZdenxbXddSP286Oido-kj0-8vVHrsFeiEVxyyIJ3i-DmALs8X6m5BnULohVyT3L27cNlMfzeYZrUaJNB57THsEuqprVoCICco28Oopuwiz5_a041DCSjQuaUXFImhpQiDsrYSU82zL1apwioeaLUMlG5FVD3E6XajNYH6N_mn4SaBUo57NcY_3X1BPUHoN_f8w
CitedBy_id	crossref_primary_10_1155_2021_3859338
Cites_doi	10.1016/j.ymben.2015.10.003 10.1016/j.cell.2012.05.044 10.1515/jib-2015-268 10.1186/s13059-017-1300-5 10.1093/nar/gku989 10.1186/1471-2164-14-513 10.1038/nbt1346 10.1093/database/bat054 10.1016/j.copbio.2013.02.007 10.1038/msb.2011.65 10.1038/nature17675 10.1093/nar/gkw1108 10.1007/978-1-61779-027-0 10.1007/s10817-014-9305-1 10.1038/s41540-018-0059-y 10.1006/ijhc.1996.0090 10.1186/2041-1480-1-S1-S3 10.1093/nar/gkx1064 10.1093/nar/gkx1132 10.1093/nar/gkv1049 10.1186/gb-2004-5-12-r101 10.1038/nbt.1666 10.1186/2041-1480-5-17 10.1145/2757001.275700 10.1093/nar/gkr469 10.1093/bioinformatics/btr164 10.1146/annurev.biochem.74.082803.133518 10.1186/gb-2005-6-5-r44 10.1073/pnas.1815288116 10.1007/978-3-540-92673-3 10.1042/BST20160436 10.1016/j.plaphy.2008.01.001 10.1016/j.websem.2006.05.005 10.1016/j.ymben.2019.06.001 10.1093/nar/gkw1092 10.1186/gb-2010-11-1-r2 10.1186/s13326-017-0165-6 10.1093/nar/gkh036 10.1093/nar/gks1146 10.1093/nar/gkw932 10.3233/SW-150200 10.1093/bioinformatics/btl208 10.7551/mitpress/3087.001.0001
ContentType	Journal Article
Copyright	The Author(s) 2020 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Distributed under a Creative Commons Attribution 4.0 International License
Copyright_xml	– notice: The Author(s) 2020 – notice: 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Distributed under a Creative Commons Attribution 4.0 International License
DBID	C6C AAYXX CITATION 3V. 7QO 7SC 7X7 7XB 88E 8AL 8AO 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABUWG AEUYN AFKRA ARAPS AZQEC BBNVY BENPR BGLVJ BHPHI CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ HCIFZ JQ2 K7- K9. L7M LK8 L~C L~D M0N M0S M1P M7P P5Z P62 P64 PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS Q9U 7X8 1XC VOOES 5PM DOA
DOI	10.1186/s12859-020-03637-9
DatabaseName	Springer Nature OA Free Journals (WRLC) CrossRef ProQuest Central (Corporate) Biotechnology Research Abstracts Computer and Information Systems Abstracts Health & Medical Collection (Proquest) ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Computing Database (Alumni Edition) ProQuest Pharma Collection Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) One Sustainability ProQuest Central UK/Ireland Advanced Technologies & Computer Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central ProQuest Technology Collection ProQuest Natural Science Collection ProQuest One ProQuest Central Engineering Research Database ProQuest Health & Medical Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Computer Science Collection Computer Science Database ProQuest Health & Medical Complete (Alumni) Advanced Technologies Database with Aerospace Biological Sciences Computer and Information Systems Abstracts Academic Computer and Information Systems Abstracts Professional Computing Database ProQuest Health & Medical Collection Medical Database Biological Science Database Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic Hyper Article en Ligne (HAL) Hyper Article en Ligne (HAL) (Open Access) PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals
DatabaseTitle	CrossRef Publicly Available Content Database Computer Science Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials ProQuest Computer Science Collection Computer and Information Systems Abstracts SciTech Premium Collection ProQuest Central China ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) Advanced Technologies & Aerospace Collection ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic ProQuest One Academic (New) Technology Collection Technology Research Database Computer and Information Systems Abstracts – Academic ProQuest One Academic Middle East (New) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central ProQuest Health & Medical Research Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Advanced Technologies Database with Aerospace ProQuest Computing ProQuest Central Basic ProQuest Computing (Alumni Edition) ProQuest SciTech Collection Computer and Information Systems Abstracts Professional Advanced Technologies & Aerospace Database ProQuest Medical Library ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic Publicly Available Content Database
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Biology Computer Science
EISSN	1471-2105
EndPage	18
ExternalDocumentID	oai_doaj_org_article_e73f4a39ba654f7aa44486cc5cf88a17 PMC7376860 oai:HAL:hal-02907978v1 10_1186_s12859_020_03637_9
GroupedDBID	--- 0R~ 23N 2WC 53G 5VS 6J9 7X7 88E 8AO 8FE 8FG 8FH 8FI 8FJ AAFWJ AAJSJ AAKPC AASML ABDBF ABUWG ACGFO ACGFS ACIHN ACIWK ACPRK ACUHS ADBBV ADMLS ADUKV AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHBYD AHMBA AHYZX ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS ARAPS AZQEC BAPOH BAWUL BBNVY BCNDV BENPR BFQNJ BGLVJ BHPHI BMC BPHCQ BVXVI C6C CCPQU CS3 DIK DU5 DWQXO E3Z EAD EAP EAS EBD EBLON EBS EMB EMK EMOBN ESX F5P FYUFA GNUQQ GROUPED_DOAJ GX1 HCIFZ HMCUK HYE IAO ICD IHR INH INR ISR ITC K6V K7- KQ8 LK8 M1P M48 M7P MK~ ML0 M~E O5R O5S OK1 OVT P2P P62 PGMZT PHGZM PHGZT PIMPY PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PUEGO RBZ RNS ROL RPM RSV SBL SOJ SV3 TR2 TUS UKHRP W2D WOQ WOW XH6 XSB AAYXX AFFHD CITATION 3V. 7QO 7SC 7XB 8AL 8FD 8FK FR3 JQ2 K9. L7M L~C L~D M0N P64 PKEHL PQEST PQUKI PRINS Q9U 7X8 1XC VOOES 5PM
ID	FETCH-LOGICAL-c551t-3beef109d801f24bfb5e70a600a1ec5f18164a0dacd76e18d0ed46e477ea174a3
IEDL.DBID	DOA
ISICitedReferencesCount	2
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000555897300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1471-2105
IngestDate	Tue Oct 14 19:02:51 EDT 2025 Tue Nov 04 01:59:59 EST 2025 Tue Oct 14 20:46:49 EDT 2025 Sun Nov 09 14:41:25 EST 2025 Mon Oct 06 18:19:22 EDT 2025 Sat Nov 29 05:40:07 EST 2025 Tue Nov 18 22:31:07 EST 2025 Sat Sep 06 07:27:25 EDT 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	1
Keywords	Ontology Logical rules Metabolic processes
Language	English
License	Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c551t-3beef109d801f24bfb5e70a600a1ec5f18164a0dacd76e18d0ed46e477ea174a3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 PMCID: PMC7376860
ORCID	0000-0003-2222-6142 0000-0002-6995-2785 0000-0001-5618-6471 0000-0002-9194-5426 0000-0003-0395-1306
OpenAccessLink	https://doaj.org/article/e73f4a39ba654f7aa44486cc5cf88a17
PMID	32703160
PQID	2435085478
PQPubID	44065
PageCount	18
ParticipantIDs	doaj_primary_oai_doaj_org_article_e73f4a39ba654f7aa44486cc5cf88a17 pubmedcentral_primary_oai_pubmedcentral_nih_gov_7376860 hal_primary_oai_HAL_hal_02907978v1 proquest_miscellaneous_2427310081 proquest_journals_2435085478 crossref_citationtrail_10_1186_s12859_020_03637_9 crossref_primary_10_1186_s12859_020_03637_9 springer_journals_10_1186_s12859_020_03637_9
PublicationCentury	2000
PublicationDate	2020-07-23
PublicationDateYYYYMMDD	2020-07-23
PublicationDate_xml	– month: 07 year: 2020 text: 2020-07-23 day: 23
PublicationDecade	2020
PublicationPlace	London
PublicationPlace_xml	– name: London
PublicationTitle	BMC bioinformatics
PublicationTitleAbbrev	BMC Bioinformatics
PublicationYear	2020
Publisher	BioMed Central Springer Nature B.V BMC
Publisher_xml	– name: BioMed Central – name: Springer Nature B.V – name: BMC
References	A Brown (3637_CR2) 2016; 534 J Hastings (3637_CR13) 2013; 41 S Naithani (3637_CR28) 2017; 45 I Andersson (3637_CR29) 2008; 46 JR Karr (3637_CR32) 2012; 150 JD Orth (3637_CR26) 2011; 7 FD Mets (3637_CR3) 2018; 116 KH Cheung (3637_CR38) 2006; 4 3637_CR1 TGO Consortium (3637_CR11) 2004; 32 U Consortium (3637_CR5) 2014; 43 3637_CR20 3637_CR21 LP Smith (3637_CR31) 2015; 12 DN Slenter (3637_CR35) 2017; 46 AL Lister (3637_CR40) 2010; 1 A Mazein (3637_CR39) 2018; 4 PL Whetzel (3637_CR8) 2011; 39 HF Kildegaard (3637_CR19) 2013; 24 3637_CR25 3637_CR47 Consortium TGO (3637_CR15) 2017; 45 B Glimm (3637_CR23) 2014; 53 K Eilbeck (3637_CR14) 2005; 6 E Demir (3637_CR18) 2010; 28 M Baron (3637_CR4) 2017; 18 ZA King (3637_CR30) 2016; 44 CJ Mungall (3637_CR43) 2010; 11 S Lohmann (3637_CR24) 2016; 7 VJ Henry (3637_CR34) 2017; 8 MA Musen (3637_CR22) 2015; 1 K Wolstencroft (3637_CR41) 2006; 22 G Van Heijst (3637_CR10) 1997; 46 D Magka (3637_CR42) 2014; 5 S Staab (3637_CR7) 2009 A Goelzer (3637_CR33) 2017; 45 DC Johnson (3637_CR6) 2005; 74 H Kitano (3637_CR45) 2001 B Smith (3637_CR9) 2007; 25 D Martin (3637_CR16) 2004; 5 M Kanehisa (3637_CR36) 2016; 45 DP Hill (3637_CR12) 2013; 14 3637_CR17 A Bulović (3637_CR27) 2019; 55 A Goelzer (3637_CR46) 2015; 32 W Blondé (3637_CR44) 2011; 27 B Glimm (3637_CR48) 2014; 53 A Fabregat (3637_CR37) 2017; 46
References_xml	– volume: 32 start-page: 232 year: 2015 ident: 3637_CR46 publication-title: Metab Eng doi: 10.1016/j.ymben.2015.10.003 – volume: 150 start-page: 389 issue: 2 year: 2012 ident: 3637_CR32 publication-title: Cell doi: 10.1016/j.cell.2012.05.044 – volume: 12 start-page: 603 issue: 2 year: 2015 ident: 3637_CR31 publication-title: J Integr Bioinformatics doi: 10.1515/jib-2015-268 – volume: 18 start-page: 159 issue: 1 year: 2017 ident: 3637_CR4 publication-title: Genome Biol doi: 10.1186/s13059-017-1300-5 – volume: 43 start-page: D204 issue: D1 year: 2014 ident: 3637_CR5 publication-title: Nucleic Acids Res doi: 10.1093/nar/gku989 – volume: 14 start-page: 513 year: 2013 ident: 3637_CR12 publication-title: BMC Genomics doi: 10.1186/1471-2164-14-513 – volume: 25 start-page: 1251 issue: 11 year: 2007 ident: 3637_CR9 publication-title: Nat Biotech doi: 10.1038/nbt1346 – ident: 3637_CR17 doi: 10.1093/database/bat054 – volume: 24 start-page: 1102 issue: 6 year: 2013 ident: 3637_CR19 publication-title: Curr Opin Biotechnol doi: 10.1016/j.copbio.2013.02.007 – volume: 7 start-page: 535 issue: 1 year: 2011 ident: 3637_CR26 publication-title: Mol Syst Biol doi: 10.1038/msb.2011.65 – volume: 534 start-page: 277 issue: 7606 year: 2016 ident: 3637_CR2 publication-title: Nature doi: 10.1038/nature17675 – volume: 45 start-page: D331 year: 2017 ident: 3637_CR15 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkw1108 – ident: 3637_CR1 doi: 10.1007/978-1-61779-027-0 – volume: 53 start-page: 245 issue: 3 year: 2014 ident: 3637_CR23 publication-title: J Autom Reason doi: 10.1007/s10817-014-9305-1 – volume: 4 start-page: 21 issue: 1 year: 2018 ident: 3637_CR39 publication-title: NPJ Syst Biol Appl doi: 10.1038/s41540-018-0059-y – volume: 46 start-page: 183 issue: 2-3 year: 1997 ident: 3637_CR10 publication-title: Int J Hum Comput Stud doi: 10.1006/ijhc.1996.0090 – ident: 3637_CR25 – volume: 1 start-page: S3 year: 2010 ident: 3637_CR40 publication-title: J Biomed Semant doi: 10.1186/2041-1480-1-S1-S3 – volume: 46 start-page: D661 issue: D1 year: 2017 ident: 3637_CR35 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkx1064 – volume: 46 start-page: D649 issue: D1 year: 2017 ident: 3637_CR37 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkx1132 – volume: 44 start-page: D515 issue: D1 year: 2016 ident: 3637_CR30 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkv1049 – volume: 5 start-page: R101 issue: 12 year: 2004 ident: 3637_CR16 publication-title: Genome Biol doi: 10.1186/gb-2004-5-12-r101 – volume: 28 start-page: 935 issue: 9 year: 2010 ident: 3637_CR18 publication-title: Nat Biotechnol doi: 10.1038/nbt.1666 – ident: 3637_CR21 – volume: 5 start-page: 17 issue: 1 year: 2014 ident: 3637_CR42 publication-title: J Biomed Semant doi: 10.1186/2041-1480-5-17 – volume: 1 start-page: 4 issue: 4 year: 2015 ident: 3637_CR22 publication-title: AI Matters doi: 10.1145/2757001.275700 – volume: 39 start-page: W541 year: 2011 ident: 3637_CR8 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkr469 – ident: 3637_CR20 – volume: 27 start-page: 1562 issue: 11 year: 2011 ident: 3637_CR44 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btr164 – volume: 53 start-page: 245 issue: 3 year: 2014 ident: 3637_CR48 publication-title: J Autom Reason doi: 10.1007/s10817-014-9305-1 – volume: 74 start-page: 247 year: 2005 ident: 3637_CR6 publication-title: Annu Rev Biochem doi: 10.1146/annurev.biochem.74.082803.133518 – volume: 6 start-page: R44 issue: 5 year: 2005 ident: 3637_CR14 publication-title: Genome Biol doi: 10.1186/gb-2005-6-5-r44 – volume: 116 start-page: 1043 issue: 3 year: 2018 ident: 3637_CR3 publication-title: Proc Nat Acad Sci doi: 10.1073/pnas.1815288116 – volume-title: Handbook on Ontologies. 2nd ed year: 2009 ident: 3637_CR7 doi: 10.1007/978-3-540-92673-3 – volume: 45 start-page: 945 issue: 4 year: 2017 ident: 3637_CR33 publication-title: Biochem Soc Trans doi: 10.1042/BST20160436 – volume: 46 start-page: 275 issue: 3 year: 2008 ident: 3637_CR29 publication-title: Plant Physiol Biochem doi: 10.1016/j.plaphy.2008.01.001 – volume: 4 start-page: 207 issue: 3 year: 2006 ident: 3637_CR38 publication-title: J Web Semant doi: 10.1016/j.websem.2006.05.005 – volume: 55 start-page: 12 year: 2019 ident: 3637_CR27 publication-title: Metab Eng doi: 10.1016/j.ymben.2019.06.001 – volume: 45 start-page: D353 issue: D1 year: 2016 ident: 3637_CR36 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkw1092 – volume: 11 start-page: R2 issue: 1 year: 2010 ident: 3637_CR43 publication-title: Genome Biol doi: 10.1186/gb-2010-11-1-r2 – volume: 8 start-page: 53 issue: 1 year: 2017 ident: 3637_CR34 publication-title: J Biomed Semant doi: 10.1186/s13326-017-0165-6 – volume: 32 start-page: D258 year: 2004 ident: 3637_CR11 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkh036 – volume: 41 start-page: D456 issue: D1 year: 2013 ident: 3637_CR13 publication-title: Nucleic Acids Res doi: 10.1093/nar/gks1146 – volume: 45 start-page: D1029 issue: Database issue year: 2017 ident: 3637_CR28 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkw932 – volume: 7 start-page: 399 issue: 4 year: 2016 ident: 3637_CR24 publication-title: Semant Web doi: 10.3233/SW-150200 – ident: 3637_CR47 – volume: 22 start-page: e530 issue: 14 year: 2006 ident: 3637_CR41 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btl208 – volume-title: Foundations of Systems Biology year: 2001 ident: 3637_CR45 doi: 10.7551/mitpress/3087.001.0001
SSID	ssj0017805
Score	2.3477259
Snippet	Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations... Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations... Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations have been... Background: Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic representations... Abstract Background Managing and organizing biological knowledge remains a major challenge, due to the complexity of living systems. Recently, systemic...
SourceID	doaj pubmedcentral hal proquest crossref springer
SourceType	Open Website Open Access Repository Aggregation Database Enrichment Source Index Database Publisher
StartPage	1
SubjectTerms	Algorithms Bioinformatics Biological activity Biomedical and Life Sciences Cognition & reasoning Computational Biology/Bioinformatics Computer Appl. in Life Sciences Computer Science Cultural heritage Formal Languages and Automata Theory Knowledge Knowledge management Knowledge representation Knowledge-based analysis Life Sciences Logical rules Metabolic processes Metabolism Methodology Methodology Article Microarrays Molecular biology Ontology Semantic web Semantics Substrates Subsystems Web Ontology Language-OWL
SummonAdditionalLinks	– databaseName: ProQuest Central dbid: BENPR link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELagBYkLb0SgIIO4gdU8bYcL6qJWPVTLCoHUm-U4drtSmyxJthL_nhnnUVKJXrjajh-ZsWfG4_mGkA-5NUXEdcZ0FlmW8lQzXYaWSS5saAvQSbkPFD4Ry6U8Pc1Xw4VbOzyrHM9Ef1CXtcE78v0Y5DqoB6mQXza_GGaNQu_qkELjLtlFpDLg893F4XL1ffIjIGL_GCoj-X4bIV4bQ5MJHZiC5TNx5FH7Qcic45vIvxTOm88lb_hMvSg6evS_i3hMHg5KKD3oueYJuWOrp-R-n5by9zPSLtarb5efqabN9sIyFHQlRZwDrKZdTT0SJkYtUV2VFN9zNfSyz7Nr6XRLRzF0BTrpcZ6QGeimD0tguEZMEkpxvpt6XXXPyc-jwx9fj9mQnIEZULI6lhTWuijMSxBxLk4LV2RWhBr0Jx1ZkznQHIDwYalNKbiNJDBAmXKbCmE1WEE6eUF2qrqyLwkFC9DkiXPCZTqViFTqYmdBkzVlIh0vAxKNNFJmQC7HBBoXylswkquergroqjxdVR6Qj9M3mx6349bWCyT91BIxt31B3ZypYQsrKxIH884LzbPUCa1TMG25MZlxUsKaAvIeGGfWx_HBicKyMM5DAfb6VRSQvZEz1HBatOqaLQLybqqGfY7OG13ZeottQNFEJCboQsz4cTbivKZan3vEcAFiRPIwIJ9Gzr0e_N9_5dXtc31NHsR-JwkWJ3tkp2u29g25Z666ddu8HXbiH1B0Pc0 priority: 102 providerName: ProQuest – databaseName: Springer LINK dbid: RSV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaggMSFNyKlIIO4gUWetsOtRVQ9VKUSD_VmOc64XalNVtlsJf59Z5wHbAVIcI0dJ_aMM99kPN8w9qYEVyXSFsIWCYhc5lbYOgahpYIYKsSkMiQKH6qjI31yUh6PSWGr6bT7FJIMX-qwrbV8v0qIa02Qu0PBRyXKm-xWQRRI5KN_-T7HDoilf0qP-e19GyYoMPWjYTmjc5C_gMzrRySvxUmD-dm__38v_oDdG-Em3x304yG7Ac0jdmcoQPnjMVvtLY4_X3zglnfrcxBk0mpOjAbUzPuWB85Lyk_itqk5ndzq-MVQURf4_D-OU5IKDjIwOpHY-XJIQBA0MyoHyikEsWwXTf-Efdv_9PXjgRjLMAiHcKoXWQXgk7is0Zj5NK98VYCKLSIlm4ArPGIEFHFcW1crCYlGUde5hFwpsOjv2Owp22raBp4xjr6eKzPvlS9sromT1KceELO6OtNe1hFLJskYN3KUU6mMcxN8FS3NsJgGF9OExTRlxN7O9ywHho6_9t4jgc89iV07XGi7UzNuVgMq8_jeZWVlkXtlbY5OrHSucF5rnFPEXqO6bIxxsHto6FqclrFCz_wyidjOpE1m_C6sTIroFEFurnTEXs3NuKMpTGMbaNfUByElcS7hEGpDCzeeuNnSLM4CN7hCg6FlHLF3ky7-fPifV2X737o_Z3fToM5KpNkO2-q7Nbxgt91lv1h1L8NuvAIAtzKm priority: 102 providerName: Springer Nature
Title	BiPOm: a rule-based ontology to represent and infer molecule knowledge from a biological process-centered viewpoint
URI	https://link.springer.com/article/10.1186/s12859-020-03637-9 https://www.proquest.com/docview/2435085478 https://www.proquest.com/docview/2427310081 https://hal.science/hal-02907978 https://pubmed.ncbi.nlm.nih.gov/PMC7376860 https://doaj.org/article/e73f4a39ba654f7aa44486cc5cf88a17
Volume	21
WOSCitedRecordID	wos000555897300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVADU databaseName: BioMed Central customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: RBZ dateStart: 20000101 isFulltext: true titleUrlDefault: https://www.biomedcentral.com/search/ providerName: BioMedCentral – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: DOA dateStart: 20000101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: M~E dateStart: 20000101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Advanced Technologies & Aerospace Database customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: P5Z dateStart: 20090101 isFulltext: true titleUrlDefault: https://search.proquest.com/hightechjournals providerName: ProQuest – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: M7P dateStart: 20090101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Computer Science Database customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: K7- dateStart: 20090101 isFulltext: true titleUrlDefault: http://search.proquest.com/compscijour providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: 7X7 dateStart: 20090101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: BENPR dateStart: 20090101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: PIMPY dateStart: 20090101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVAVX databaseName: Springer LINK customDbUrl: eissn: 1471-2105 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017805 issn: 1471-2105 databaseCode: RSV dateStart: 20001201 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwELdggMQL4lMLjMog3sBaPhzb4W1Fm4YYJRofKrxYjmNrlba0atNJ_PfcOUlZJwEvvFhq7DjR3Tl317v7HSGvCmerRJicmTxxjAtumKljx5SQLnYV2KQiFAqfyMlETadFeaXVF-aEdfDAHeH2ncw8N1lRGZFzL43h4FAIa3PrlTJJqCOPZTE4U338AJH6hxIZJfZXCeK0MXSVMHApWbGlhgJaPyiXM8yFvGJoXk-TvBYrDSro6D6519uO9KB75wfkhmsekjtdN8mfj8hqPCs_Xbylhi7X546hfqopwhPgNG3nNABYYrERNU1NMQ1rSS-69riObv5co1hxApt08EzIQ7roqgkYviL29qQYT1jMZ037mHw9Ovzy7pj1PRWYBduoZVnlnE_iogbN5FNe-Sp3MjZg9pjE2dyDwgd-xbWxtRQuUcC3mgvHpXRAbGDEE7LTzBu3Syg4brbIvJc-N1whwKhPvQMD1NaZ8qKOSDKQWNsecBz7Xpzr4HgooTu2aGCLDmzRRUReb-5ZdHAbf109Rs5tViJUdrgAAqR7AdL_EqCIvAS-b-1xfHCi8VqcFiBaUl0mEdkbxEL3h3ylUzA1wWLlUkXkxWYajifGXEzj5mtcA_YhAijBFnJLnLaeuD3TzM4C0LeEr78ScUTeDIL3--F_psrT_0GVZ-RuGo6LZGm2R3ba5do9J7ftZTtbLUfkppzKMKoRuTU-nJSno3AAYfwg2QgzaEsYy_wHzJfvP5bf4dfp52-_ADOjN-4
linkProvider	Directory of Open Access Journals
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VAoILb0SggEFwAqt52g4SQi1QbbXL0kORejOOY9OV2mTZR1H_FL-RmWSzZSvRWw9cY8dxnM_zyHi-AXiVO1tEwmTcZJHjqUgNN2XouBLSha5Am1Q0icIDORyqg4N8bw1-d7kwdKyyk4mNoC5rS__IN2PU62gepFJ9GP_kVDWKoqtdCY0WFn13-gtdtun73U_4fV_H8c7n_Y89vqgqwC1aBzOeFM75KMxLlM0-TgtfZE6GBhW_iZzNPKo8nHFYGltK4SKFMy9T4VIpnUHz3SQ47hW4miZKEFd_X_Jl1ILqA3SJOUpsTiNih-PkoFG4VPJ8Rfk1NQJQpR3SCcy_zNvzhzPPRWgbxbdz-39bsjtwa2Fis612T9yFNVfdg-tt0c3T-zDdHu19PX7HDJvMjxwnNV4yYnGgZjarWcPzSTlZzFQlo9NqE3bcVhF2bPkPklFiDg7SslgR1Nm4TbrgtKZUApXR-ozrUTV7AN8u5Y0fwnpVV-4RMPRvbZ54L31mUkU8rD72Du10WybKizKAqMOEtgtedioPcqQb_0wJ3eJII450gyOdB_Bmec-4ZSW5sPc2QW3ZkxjFmwv15IdeCCjtZOJx3nlhRJZ6aUyKjruwNrNeKXynAF4iUFfG6G0NNF0L4zyUuVQnUQAbHRL1QhZO9RkMA3ixbEYpRqEpU7l6Tn3QjCaeKRxCruB_5YmrLdXosOFDl6gklQgDeNvtlLOH_3tVHl881-dwo7f_ZaAHu8P-E7gZN7tY8jjZgPXZZO6ewjV7MhtNJ88aGcDg-2XvoD8IVprN
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELagQMWFZ1EDBQziBlbztB1uLbAqYrWseKk3y3FsulKbrLLZSvx7ZpxkaSpAQlzjV2yPM99kPN8Q8iK3poi4zpjOIstSnmqmy9AyyYUNbQGYlPtA4amYzeTxcT6_EMXvb7sPLskupgFZmqp2f1m67ohLvr-KkHeNoemDjkjB8qvkWgqWDMr4p8_fNn4EZOwfQmV-226kjjxrPyiZE7wTeQFwXr4uecln6lXR5Pb_T-IOudXDUHrQyc1dcsVW98iNLjHlj_tkdbiYfzx7TTVt1qeWoaorKTIdYDFta-q5MDFuieqqpHijq6FnXaZdSzf_6SgGr0AnHdMTigNddoEJDGeJaUIpuiaW9aJqd8jXybsvb45Yn56BGYBZLUsKa10U5iUoORenhSsyK0INCEpH1mQOsANsfVhqUwpuIwkiUKbcpkJYDXaQTh6Qraqu7C6hYAOaPHFOuEynErlKXewsYFlTJtLxMiDRsEvK9NzlmELjVHkbRnLVLaaCxVR-MVUekJebNsuOueOvtQ9x8zc1kXXbP6ib76o_xMqKxMF754XmWeqE1ikYt9yYzDgpYU4BeQ6iM-rj6GCq8FkY56EAi_08CsjeIFmq_16sVAyoFcBvKmRAnm2K4aSj-0ZXtl5jHYCayMUEXYiRRI5GHJdUixPPGS5AkUgeBuTVIJe_Bv_zqjz8t-pPyfb87URN388-PCI3Yy_ZgsXJHtlqm7V9TK6b83axap74Q_oTSto-bg
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=BiPOm%3A+a+rule-based+ontology+to+represent+and+infer+molecule+knowledge+from+a+biological+process-centered+viewpoint&rft.jtitle=BMC+bioinformatics&rft.au=Henry%2C+Vincent&rft.au=Sa%C3%AFs%2C+Fatiha&rft.au=Inizan%2C+Olivier&rft.au=Marchadier%2C+Elodie&rft.date=2020-07-23&rft.issn=1471-2105&rft.eissn=1471-2105&rft.volume=21&rft.issue=1&rft_id=info:doi/10.1186%2Fs12859-020-03637-9&rft.externalDBID=n%2Fa&rft.externalDocID=10_1186_s12859_020_03637_9
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1471-2105&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1471-2105&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1471-2105&client=summon