Quantitative analysis by next generation sequencing of hematopoietic stem and progenitor cells (LSK) and of splenic B cells transcriptomes from wild-type and Usp3-knockout mice

The data described here provide genome-wide expression profiles of murine primitive hematopoietic stem and progenitor cells (LSK) and of B cell populations, obtained by high throughput sequencing. Cells are derived from wild-type mice and from mice deficient for the ubiquitin-specific protease 3 (US...

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Vydáno v:	Data in brief Ročník 6; s. 556 - 561
Hlavní autoři:	Lancini, Cesare, Gargiulo, Gaetano, van den Berk, Paul C.M., Citterio, Elisabetta
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier Inc 01.03.2016 Elsevier
Témata:	B cell B-lymphocytes Data data collection Deubiquitinating enzymes (DUBs) DNA DNA damage DNA damage response (DDR) DNA double-strand breaks (DSBs) gene expression hematopoiesis Hematopoietic stem and progenitor cells (HSPC) Hematopoietic stem cells (HSC) Histone H2A histones homeostasis LSK mice proteinases quantitative analysis quantitative polymerase chain reaction RNA-seq transcription (genetics) Transcriptional profiling transcriptome Ubiquitin Ubiquitin-specific protease 3 (USP3) ubiquitination Ubiquitin DUBs Deubiquitinating enzymes (DUBs) Hematopoietic stem cells (HSC) Histone H2A LSK USP3 DNA damage response (DDR) BM Ub B cell Hematopoietic stem and progenitor cells (HSPC) DDR Ubiquitin-specific protease 3 (USP3) RNA-seq HSC Transcriptional profiling DNA double-strand breaks (DSBs) DUBs, deubiquitinating enzymes LSK, Lin-Sca1+ cKit+ cells BM, bone marrow HSC, hematopoietic stem cell Ub, ubiquitin RNA-seq, RNA sequencing USP3, Ub-specific protease 3 DDR, DNA damage response
ISSN:	2352-3409, 2352-3409
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