Wnt signaling in cancer

Wnt signaling is one of the key cascades regulating development and stemness, and has also been tightly associated with cancer. The role of Wnt signaling in carcinogenesis has most prominently been described for colorectal cancer, but aberrant Wnt signaling is observed in many more cancer entities....

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Veröffentlicht in:	Oncogene Jg. 36; H. 11; S. 1461 - 1473
Hauptverfasser:	Zhan, T, Rindtorff, N, Boutros, M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.03.2017 Nature Publishing Group
Schlagworte:	631/67 631/67/68 631/80/86 Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Apoptosis beta Catenin - metabolism Cancer Carcinogenesis Cell Biology Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Cellular signal transduction Genetic aspects Health aspects Human Genetics Humans Internal Medicine Medicine Medicine & Public Health Molecular Targeted Therapy Mutation Neoplasm Metastasis Neoplasms - drug therapy Neoplasms - etiology Neoplasms - metabolism Neoplasms - pathology Neoplastic Stem Cells - drug effects Neoplastic Stem Cells - metabolism Oncogenes Oncology Protein Binding Protein expression Review Signal transduction Tumor Escape - immunology Tumorigenesis Wnt Proteins - metabolism Wnt Signaling Pathway - drug effects
ISSN:	0950-9232, 1476-5594, 1476-5594
Online-Zugang:	Volltext
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