Needles in the blue sea: Sub-species specificity in targeted protein biomarker analyses within the vast oceanic microbial metaproteome

Proteomics has great potential for studies of marine microbial biogeochemistry, yet high microbial diversity in many locales presents us with unique challenges. We addressed this challenge with a targeted metaproteomics workflow for NtcA and P‐II, two nitrogen regulatory proteins, and demonstrated i...

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Veröffentlicht in:	Proteomics (Weinheim) Jg. 15; H. 20; S. 3521 - 3531
Hauptverfasser:	Saito, Mak A., Dorsk, Alexander, Post, Anton F., McIlvin, Matthew R., Rappé, Michael S., DiTullio, Giacomo R., Moran, Dawn M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany Blackwell Publishing Ltd 01.10.2015 Wiley Subscription Services, Inc
Schlagworte:	Biogeochemistry Biomarkers Cyanobacteria Gene mapping Genetic Variation Genomes Humans Metagenome Metatryp Microbiology Microorganisms MRM Needles Nitrogen Oceans and Seas Peptide mapping Peptides Phylogeny Prochlorococcus Prochlorococcus - genetics Proteins Proteome - genetics Proteomics Python Regulatory proteins Species Species Specificity Synechococcus Synechococcus - genetics Targeted metaproteomics Tryptic peptides Workflow Pacific Ocean Biomarkers MRM Microbiology Metatryp Targeted metaproteomics Cyanobacteria
ISSN:	1615-9853, 1615-9861
Online-Zugang:	Volltext
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