A Focus on the Pathophysiology of Adrenomedullin Expression: Endothelitis and Organ Damage in Severe Viral and Bacterial Infections

Adrenomedullin (ADM) is a peptide hormone produced primarily in the adrenal glands, playing a crucial role in various physiological processes. As well as improving vascular integrity and decreasing vascular permeability, ADM acts as a vasodilator, positive inotrope, diuretic, natriuretic and broncho...

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Bibliographic Details
Published in:	Cells (Basel, Switzerland) Vol. 13; no. 11; p. 892
Main Authors:	Spoto, Silvia, Basili, Stefania, Cangemi, Roberto, Yuste, José Ramón, Lucena, Felipe, Romiti, Giulio Francesco, Raparelli, Valeria, Argemi, Josepmaria, D’Avanzo, Giorgio, Locorriere, Luciana, Masini, Francesco, Calarco, Rodolfo, Testorio, Giulia, Spiezia, Serenella, Ciccozzi, Massimo, Angeletti, Silvia
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.06.2024 MDPI
Subjects:	Adrenal glands Adrenomedullin adrenomedullin (ADM) Adrenomedullin - metabolism Aldosterone Amino acids Angiogenesis Angiotensin Angiotensin II Animals Antibiotics Apoptosis B cells Bacteria Bacterial infections Bacterial Infections - complications Bacterial Infections - metabolism Biomarkers Blood vessels Coronaviruses Corticosteroids COVID-19 Cytokines Dilatation Diuretics endothelitis Health aspects Humans Hypoxia Immunoregulation Infection Infections Inflammation Inflammation - pathology Influenza Kinases mid-regional proadrenomedullin (MR-proADM) Mortality Nitric oxide Peptides Permeability Physiological aspects Physiology Review Sepsis Spain Tumor necrosis factor-TNF United Kingdom Vasodilators viral infection Viral infections Virus Diseases - complications Virus Diseases - metabolism United Kingdom Spain endothelitis viral infection adrenomedullin (ADM) biomarkers sepsis mid-regional proadrenomedullin (MR-proADM)
ISSN:	2073-4409, 2073-4409
Online Access:	Get full text
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