Sex-Specific Impact of Fkbp5 on Hippocampal Response to Acute Alcohol Injection: Involvement in Alterations of Metabolism-Related Pathways

High levels of alcohol intake alter brain gene expression and can produce long-lasting effects. FK506-binding protein 51 (FKBP51) encoded by Fkbp5 is a physical and cellular stress response gene and has been associated with alcohol consumption and withdrawal severity. Fkbp5 has been previously linke...

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Bibliographic Details
Published in:	Cells (Basel, Switzerland) Vol. 13; no. 1; p. 89
Main Authors:	Williams, Kent E., Zou, Yi, Qiu, Bin, Kono, Tatsuyoshi, Guo, Changyong, Garcia, Dawn, Chen, Hanying, Graves, Tamara, Lai, Zhao, Evans-Molina, Carmella, Ma, Yao-Ying, Liangpunsakul, Suthat, Yong, Weidong, Liang, Tiebing
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 31.12.2023 MDPI
Subjects:	Alcohol Drinking Alcohol use Alcohol-Related Disorders Animals Axon guidance Axonogenesis Brain research Calcium metabolism Calcium signalling Cell signaling Cellular signal transduction Cellular stress response Cytology Drinking of alcoholic beverages Drug dosages Epigenetics Ethanol Ethanol - pharmacology Female Females Fkbp5 Gender differences Gene expression Genetic aspects Glycine Health aspects Hippocampus Hippocampus (Brain) Injections Laboratory animals Lipid Metabolism Male Metabolic regulation Mice mitochondria Morphology Neurons Neuroprotection Physiological aspects Post-translation Potassium Proteins RNA-seq Sex differences Signal transduction Software Tacrolimus Tacrolimus-binding protein United States United States > US RNA-seq hippocampus mitochondria Fkbp5 lipid metabolism
ISSN:	2073-4409, 2073-4409
Online Access:	Get full text
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