Recovery of a Medieval Brucella melitensis Genome Using Shotgun Metagenomics

Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male excavated from the medieval Sardinian settlement of...

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Bibliographic Details
Published in:	mBio Vol. 5; no. 4; pp. e01337 - 14
Main Authors:	Kay, Gemma L., Sergeant, Martin J., Giuffra, Valentina, Bandiera, Pasquale, Milanese, Marco, Bramanti, Barbara, Bianucci, Raffaella, Pallen, Mark J.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 15.07.2014 American Society of Microbiology
Subjects:	bioinformatics Biological anthropology Brucella melitensis Brucella melitensis - genetics Brucellosis Calcification DNA DNA sequencing evolution genome Genome, Bacterial - genetics Genomes Human remains Humanities and Social Sciences humans Infections Infectious diseases Italy Leprosy males Mediterranean region Metagenomics Metagenomics - methods middle-aged adults Nucleotide sequence nucleotide sequences Pathogens Phylogenetics sequence analysis Single-nucleotide polymorphism skeleton Tuberculosis Italy Mediterranean region Shotgun Metagenomics Medieval Brucella melitensis Genome
ISSN:	2161-2129, 2150-7511, 2150-7511
Online Access:	Get full text
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