Recovery of a Medieval Brucella melitensis Genome Using Shotgun Metagenomics

Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male excavated from the medieval Sardinian settlement of...

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Veröffentlicht in:	mBio Jg. 5; H. 4; S. e01337 - 14
Hauptverfasser:	Kay, Gemma L., Sergeant, Martin J., Giuffra, Valentina, Bandiera, Pasquale, Milanese, Marco, Bramanti, Barbara, Bianucci, Raffaella, Pallen, Mark J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States American Society for Microbiology 15.07.2014 American Society of Microbiology
Schlagworte:	bioinformatics Biological anthropology Brucella melitensis Brucella melitensis - genetics Brucellosis Calcification DNA DNA sequencing evolution genome Genome, Bacterial - genetics Genomes Human remains Humanities and Social Sciences humans Infections Infectious diseases Italy Leprosy males Mediterranean region Metagenomics Metagenomics - methods middle-aged adults Nucleotide sequence nucleotide sequences Pathogens Phylogenetics sequence analysis Single-nucleotide polymorphism skeleton Tuberculosis Italy Mediterranean region Shotgun Metagenomics Medieval Brucella melitensis Genome
ISSN:	2161-2129, 2150-7511, 2150-7511
Online-Zugang:	Volltext
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