Heparin-induced thrombocytopenia (HIT II) - a drug-associated autoimmune disease

Autoimmune thrombocytopenia (ITP) is an acquired autoimmune disease characterised by isolated persistent thrombocytopenia and normal megakaryopoiesis. This definition also applies to heparin-induced thrombocytopenia (HIT II), a frequent side effect of heparin treatment. In HIT II, the immunogen is a...

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Bibliographic Details
Published in:	Thrombosis and haemostasis Vol. 102; no. 5; p. 887
Main Author:	Nowak, Götz
Format:	Journal Article
Language:	English
Published:	Germany 01.11.2009
Subjects:	Adult Aged Anticoagulants - adverse effects Anticoagulants - immunology Anticoagulants - pharmacology Anticoagulants - therapeutic use Autoantibodies - biosynthesis Autoantibodies - blood Autoantibodies - immunology Citrates - pharmacology Early Diagnosis Female Heart Diseases - complications Heart Diseases - drug therapy Heart Diseases - immunology Heparin - adverse effects Heparin - immunology Heparin - pharmacology Heparin - therapeutic use Humans Immunoglobulin G - analysis Immunoglobulin G - biosynthesis Immunoglobulin G - immunology Kidney Failure, Chronic - complications Kidney Failure, Chronic - drug therapy Kidney Failure, Chronic - immunology Male Models, Immunological Platelet Adhesiveness Platelet Count - methods Platelet Factor 4 - drug effects Platelet Factor 4 - immunology Purpura, Thrombocytopenic, Idiopathic - chemically induced Purpura, Thrombocytopenic, Idiopathic - complications Purpura, Thrombocytopenic, Idiopathic - diagnosis Purpura, Thrombocytopenic, Idiopathic - immunology Receptors, IgG - immunology Renal Dialysis Stroke - complications Stroke - drug therapy Stroke - immunology
ISSN:	0340-6245, 2567-689X, 2567-689X
Online Access:	Get more information
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