Making the Leap from Research Laboratory to Clinic: Challenges and Opportunities for Next-Generation Sequencing in Infectious Disease Diagnostics

Next-generation DNA sequencing (NGS) has progressed enormously over the past decade, transforming genomic analysis and opening up many new opportunities for applications in clinical microbiology laboratories. The impact of NGS on microbiology has been revolutionary, with new microbial genomic sequen...

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Bibliographic Details
Published in:	mBio Vol. 6; no. 6; p. e01888
Main Authors:	Goldberg, Brittany, Sichtig, Heike, Geyer, Chelsie, Ledeboer, Nathan, Weinstock, George M.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 08.12.2015 American Society of Microbiology
Subjects:	Antibiotics Antimicrobial agents Bacteria Clinical microbiology Clinical trials Communicable Diseases - diagnosis Disease control DNA sequencing Drug resistance Encephalitis Epidemics Genes Genomic analysis High-Throughput Nucleotide Sequencing - methods High-Throughput Nucleotide Sequencing - standards High-Throughput Nucleotide Sequencing - trends HIV Human immunodeficiency virus Infectious diseases Laboratories Metabolism Metagenomics Microbiological Techniques - methods Microbiological Techniques - standards Microbiological Techniques - trends Microbiomes Minireview Molecular Diagnostic Techniques - methods Molecular Diagnostic Techniques - standards Molecular Diagnostic Techniques - trends Mutation Next-generation sequencing Organisms Polymorphism Societies, Scientific Staphylococcus infections Technology adoption United States Viruses Whole genome sequencing United States
ISSN:	2161-2129, 2150-7511, 2150-7511
Online Access:	Get full text
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