Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation

Synaptic long-term potentiation (LTP) is a key mechanism involved in learning and memory, and its alteration is associated with mental disorders. Shank3 is a major postsynaptic scaffolding protein that orchestrates dendritic spine morphogenesis, and mutations of this protein lead to mental retardati...

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Bibliographic Details
Published in:	The Journal of neuroscience Vol. 33; no. 23; p. 9699
Main Authors:	Raynaud, Fabrice, Janossy, Andrea, Dahl, Janine, Bertaso, Federica, Perroy, Julie, Varrault, Annie, Vidal, Michel, Worley, Paul F, Boeckers, Tobias M, Bockaert, Joël, Marin, Philippe, Fagni, Laurent, Homburger, Vincent
Format:	Journal Article
Language:	English
Published:	United States 05.06.2013
Subjects:	Amino Acid Sequence Animals Dendritic Spines - metabolism Exocytosis - physiology Female GTPase-Activating Proteins - genetics GTPase-Activating Proteins - metabolism HEK293 Cells Hippocampus - metabolism Humans Long-Term Potentiation - physiology Male Mice Microfilament Proteins Molecular Sequence Data Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Organ Culture Techniques Protein Binding - physiology Random Allocation Rats Rats, Sprague-Dawley Receptors, AMPA - metabolism Synapses - metabolism
ISSN:	1529-2401, 1529-2401
Online Access:	Get more information
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