ER stress and unfolded protein response in ocular health and disease

The human eye is the organ that is able to react to light in order to provide sharp three‐dimensional and colored images. Unfortunately, the health of the eye can be impacted by various stimuli that can lead to vision loss, such as environmental changes, genetic mutations, or aging. Endoplasmic reti...

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Veröffentlicht in:	The FEBS journal Jg. 286; H. 2; S. 399 - 412
Hauptverfasser:	Kroeger, Heike, Chiang, Wei‐Chieh, Felden, Julia, Nguyen, Amanda, Lin, Jonathan H.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Blackwell Publishing Ltd 01.01.2019
Schlagworte:	achromatopsia Aging AMD Animal models Animals color Endoplasmic reticulum Endoplasmic Reticulum - metabolism Endoplasmic Reticulum - pathology Endoplasmic Reticulum Stress Environmental changes ER stress Eye - metabolism Eye diseases Eye Diseases - physiopathology eyes glaucoma Humans Mutation neurodegernation Organic chemistry Protein folding Proteins retinal degeneration RGC RPE Signal Transduction Stress Unfolded Protein Response UPR VEGF vision retinal degeneration RPE UPR VEGF glaucoma AMD ER stress achromatopsia neurodegernation RGC
ISSN:	1742-464X, 1742-4658, 1742-4658
Online-Zugang:	Volltext
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