Physical Exercise Induces Significant Changes in Immunoglobulin G N-Glycan Composition in a Previously Inactive, Overweight Population
Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a...
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| Vydáno v: | Biomolecules (Basel, Switzerland) Ročník 13; číslo 5; s. 762 |
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| Abstract | Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10−4, 2.41 × 10−25, 1.51 × 10−21 and 3.38 × 10−30, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10−12, 7.61 × 10−9 and 1.09 × 10−28, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10−16), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction. |
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| AbstractList | Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (
= 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10
, 2.41 × 10
, 1.51 × 10
and 3.38 × 10
, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10
, 7.61 × 10
and 1.09 × 10
, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10
), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction. Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10-4, 2.41 × 10-25, 1.51 × 10-21 and 3.38 × 10-30, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10-12, 7.61 × 10-9 and 1.09 × 10-28, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10-16), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction.Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10-4, 2.41 × 10-25, 1.51 × 10-21 and 3.38 × 10-30, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10-12, 7.61 × 10-9 and 1.09 × 10-28, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10-16), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction. Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10−4, 2.41 × 10−25, 1.51 × 10−21 and 3.38 × 10−30, respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10−12, 7.61 × 10−9 and 1.09 × 10−28, respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10−16), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction. Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflammatory status by monitoring IgG N-glycosylation in a previously inactive, middle-aged, overweight and obese population (50.30 ± 9.23 years, BMI 30.57 ± 4.81). Study participants (N = 397) underwent one of three different exercise programs lasting three months with blood samples collected at baseline and at the end of intervention. After chromatographically profiling IgG N-glycans, linear mixed models with age and sex adjustment were used to investigate exercise effects on IgG glycosylation. Exercise intervention induced significant changes in IgG N-glycome composition. We observed an increase in agalactosylated, monogalctosylated, asialylated and core-fucosylated N-glycans (padj = 1.00 × 10[sup.−4] , 2.41 × 10[sup.−25] , 1.51 × 10[sup.−21] and 3.38 × 10[sup.−30] , respectively) and a decrease in digalactosylated, mono- and di-sialylated N-glycans (padj = 4.93 × 10[sup.−12] , 7.61 × 10[sup.−9] and 1.09 × 10[sup.−28] , respectively). We also observed a significant increase in GP9 (glycan structure FA2[3]G1, β = 0.126, padj = 2.05 × 10[sup.−16] ), previously reported to have a protective cardiovascular role in women, highlighting the importance of regular exercise for cardiovascular health. Other alterations in IgG N-glycosylation reflect an increased pro-inflammatory IgG potential, expected in a previously inactive and overweight population, where metabolic remodeling is in the early stages due to exercise introduction. |
| Audience | Academic |
| Author | Očić, Mateja Deriš, Helena Zekić, Robert Frkatović-Hodžić, Azra Šimunić-Briški, Nina Knjaz, Damir Dukarić, Vedran Lauc, Gordan |
| AuthorAffiliation | 1 Genos Ltd., 10000 Zagreb, Croatia 3 Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia 2 Faculty of Kinesiology, University of Zagreb, 10000 Zagreb, Croatia |
| AuthorAffiliation_xml | – name: 2 Faculty of Kinesiology, University of Zagreb, 10000 Zagreb, Croatia – name: 3 Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia – name: 1 Genos Ltd., 10000 Zagreb, Croatia |
| Author_xml | – sequence: 1 givenname: Nina surname: Šimunić-Briški fullname: Šimunić-Briški, Nina – sequence: 2 givenname: Robert surname: Zekić fullname: Zekić, Robert – sequence: 3 givenname: Vedran surname: Dukarić fullname: Dukarić, Vedran – sequence: 4 givenname: Mateja orcidid: 0000-0003-4723-4093 surname: Očić fullname: Očić, Mateja – sequence: 5 givenname: Azra orcidid: 0000-0002-0751-4421 surname: Frkatović-Hodžić fullname: Frkatović-Hodžić, Azra – sequence: 6 givenname: Helena orcidid: 0000-0003-3944-7881 surname: Deriš fullname: Deriš, Helena – sequence: 7 givenname: Gordan orcidid: 0000-0003-1840-9560 surname: Lauc fullname: Lauc, Gordan – sequence: 8 givenname: Damir surname: Knjaz fullname: Knjaz, Damir |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37238633$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1038_s41588_025_02260_9 crossref_primary_10_1080_14728222_2023_2277218 crossref_primary_10_1002_mco2_760 crossref_primary_10_1097_MD_0000000000042440 crossref_primary_10_1111_imr_13407 crossref_primary_10_3390_jcm14051626 crossref_primary_10_1007_s10719_023_10144_5 |
| Cites_doi | 10.3389/fimmu.2022.995186 10.1055/s-0030-1268461 10.5040/9781492595717.ch-001 10.1249/MSS.0b013e318213fefb 10.3389/fmed.2018.00061 10.1074/mcp.M111.010090 10.1161/CIRCULATIONAHA.110.003236 10.1089/met.2016.0094 10.1016/j.carres.2009.04.031 10.3389/fimmu.2018.00648 10.1016/j.bbagen.2016.05.001 10.1053/j.gastro.2019.08.060 10.2337/dc22-0833 10.1186/1471-2458-12-704 10.1007/978-3-030-24970-0 10.1097/00005768-199901000-00008 10.1056/NEJMoa011858 10.1093/intimm/dxx038 10.1016/j.arr.2012.03.003 10.7326/0003-4819-132-8-200004180-00002 10.1038/s41366-021-00816-3 10.1590/S1517-86922012000300015 10.1016/j.mad.2006.11.016 10.1006/pmed.2001.0909 10.3389/fphys.2019.01522 10.1152/japplphysiol.00073.2002 10.1038/s41598-017-12495-0 10.1016/j.cellimm.2018.07.009 10.1007/s00408-013-9483-3 10.6063/motricidade.10049 10.1016/j.imbio.2018.10.002 10.1111/j.1600-0838.2012.01462.x 10.3389/fimmu.2019.00907 10.1016/bs.mie.2016.09.027 10.1002/cphy.c110025 10.1016/S0140-6736(12)60898-8 10.1371/journal.pone.0168503 10.1002/jcb.27810 10.14336/AD.2018.0326 10.1152/japplphysiol.00123.2005 10.1093/glycob/cwz061 10.3390/antiox7010017 10.2337/dc19-1507 |
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| Keywords | IgG exercise glycosylation N-glycans inflammation sedentary population |
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| References | Plomp (ref_42) 2017; 7 Lauc (ref_24) 2016; 1860 Bok (ref_36) 2019; 10 Flynn (ref_31) 2019; 10 Blair (ref_5) 2012; 22 Booth (ref_9) 2002; 93 Guseman (ref_6) 2017; 15 Booth (ref_10) 2012; 2 Blair (ref_2) 2009; 43 Greto (ref_33) 2021; 45 Franceschi (ref_26) 2018; 5 Winnet (ref_47) 2001; 33 Kiyoshi (ref_45) 2017; 29 Terra (ref_22) 2017; 13 Russell (ref_32) 2019; 224 Wittenbecher (ref_41) 2020; 43 Takahashi (ref_44) 2009; 344 ref_20 Myers (ref_11) 2002; 346 Antunes (ref_19) 2018; 120 Sarin (ref_35) 2019; 10 Simpson (ref_16) 2012; 11 ref_29 Fabre (ref_48) 2011; 32 Bradshaw (ref_27) 2023; Volume 4 Terra (ref_21) 2012; 18 Tominac (ref_34) 2022; 13 Adamczyk (ref_38) 2011; 10 Zahavi (ref_43) 2018; 1 Franceschi (ref_30) 2007; 128 Wei (ref_14) 2000; 132 Ugrina (ref_39) 2017; 586 Kohl (ref_4) 2012; 380 Vilaj (ref_37) 2019; 29 Campbell (ref_18) 2018; 9 Verhelst (ref_25) 2020; 158 Bradshaw (ref_28) 2023; Volume 4 Birukov (ref_40) 2022; 45 Gleeson (ref_17) 2015; 28 Holloszy (ref_15) 2005; 99 Gudelj (ref_23) 2018; 333 Schneider (ref_13) 2013; 191 Feigenbaum (ref_46) 1999; 31 ref_1 ref_3 ref_49 ref_8 Gupta (ref_12) 2011; 123 ref_7 |
| References_xml | – volume: 13 start-page: 995186 year: 2022 ident: ref_34 article-title: Effects of low-calorie and different weight-maintenance diets on IgG glycomecomposition publication-title: Front. Immunol. doi: 10.3389/fimmu.2022.995186 – volume: 32 start-page: 407 year: 2011 ident: ref_48 article-title: Efficacy of Nordic Walking in Obesity Management publication-title: Int. J. Sport. Med. doi: 10.1055/s-0030-1268461 – ident: ref_3 doi: 10.5040/9781492595717.ch-001 – volume: 1 start-page: 7 year: 2018 ident: ref_43 article-title: Enhancing antibody-dependent cell-mediated cytotoxicity: A strategy for improving antibody-based immunotherapy publication-title: Antib. Ther. – ident: ref_8 doi: 10.1249/MSS.0b013e318213fefb – volume: 5 start-page: 61 year: 2018 ident: ref_26 article-title: Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates publication-title: Front. Med. doi: 10.3389/fmed.2018.00061 – volume: 10 start-page: M111.010090 year: 2011 ident: ref_38 article-title: High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations publication-title: Mol. Cell Proteom. doi: 10.1074/mcp.M111.010090 – volume: 123 start-page: 1377 year: 2011 ident: ref_12 article-title: Cardiorespiratory fitness and classification of risk of cardiovascular disease mortality publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.110.003236 – volume: 15 start-page: 107 year: 2017 ident: ref_6 article-title: The association between measures of fitness and metabolic health in treatment- seeking youth with obesity publication-title: Metab. Syndr. Relat. Disord. doi: 10.1089/met.2016.0094 – volume: 344 start-page: 1387 year: 2009 ident: ref_44 article-title: Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: Their functions and target proteins publication-title: Carbohydr. Res. doi: 10.1016/j.carres.2009.04.031 – volume: 9 start-page: 648 year: 2018 ident: ref_18 article-title: Debunking the Myth of Exercise- Induced Immune Suppression: Redefining the Impact of Exercise on Immunological Health Across the Lifespan publication-title: Front. Immunol. doi: 10.3389/fimmu.2018.00648 – volume: 1860 start-page: 1571 year: 2016 ident: ref_24 article-title: Precision medicine that transcends genomics: Glycans as integrators of genes and environment publication-title: BBA Gen. Subj. doi: 10.1016/j.bbagen.2016.05.001 – ident: ref_1 – volume: 158 start-page: 95 year: 2020 ident: ref_25 article-title: Protein Glycosylation as a Diagnostic and Prognostic Marker of Chronic Inflammatory Gastrointestinal and Liver Diseases publication-title: Gastroenterology doi: 10.1053/j.gastro.2019.08.060 – volume: 45 start-page: 2729 year: 2022 ident: ref_40 article-title: Immunoglobulin G N-Glycosylation Signatures in Incident Type 2 Diabetes and Cardiovascular Disease publication-title: Diabetes Care doi: 10.2337/dc22-0833 – ident: ref_49 doi: 10.1186/1471-2458-12-704 – ident: ref_29 doi: 10.1007/978-3-030-24970-0 – volume: 31 start-page: 38 year: 1999 ident: ref_46 article-title: Prescription of resistance training for health and disease publication-title: Med. Sci. Sport. Exerc. doi: 10.1097/00005768-199901000-00008 – volume: 346 start-page: 793 year: 2002 ident: ref_11 article-title: Exercise capacity and mortality among men referred for exercise testing publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa011858 – volume: 29 start-page: 311 year: 2017 ident: ref_45 article-title: Glycosylation of IgG-Fc: A molecular perspective publication-title: Int. Immunol. doi: 10.1093/intimm/dxx038 – volume: 11 start-page: 404 year: 2012 ident: ref_16 article-title: Exercise and the aging immune system publication-title: Ageing Res. Rev. doi: 10.1016/j.arr.2012.03.003 – volume: 132 start-page: 605 year: 2000 ident: ref_14 article-title: Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes publication-title: Ann. Intern. Med. doi: 10.7326/0003-4819-132-8-200004180-00002 – volume: 45 start-page: 1521 year: 2021 ident: ref_33 article-title: Extensive weight loss reduces glycan age by altering IgG N-glycosylation publication-title: Int. J. Obes. doi: 10.1038/s41366-021-00816-3 – volume: 18 start-page: 208 year: 2012 ident: ref_21 article-title: Effect of exercise on the immune system: Response, adaptation and cell signaling publication-title: Rev. Bras. Med. Esport doi: 10.1590/S1517-86922012000300015 – volume: 128 start-page: 92 year: 2007 ident: ref_30 article-title: Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans publication-title: Mech. Ageing Dev. doi: 10.1016/j.mad.2006.11.016 – volume: 33 start-page: 503 year: 2001 ident: ref_47 article-title: Potential Health-Related Benefits of Resistance Training publication-title: Prevent Med. doi: 10.1006/pmed.2001.0909 – volume: 10 start-page: 1522 year: 2019 ident: ref_36 article-title: Intense Physical Exercise Induces an Anti-inflammatory Change in IgG N-Glycosylation Profile publication-title: Front. Physiol. doi: 10.3389/fphys.2019.01522 – volume: 93 start-page: 3 year: 2002 ident: ref_9 article-title: Waging war on physical inactivity: Using modern molecular ammunition against an ancient enemy publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.00073.2002 – volume: 7 start-page: 12325 year: 2017 ident: ref_42 article-title: Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health publication-title: Sci. Rep. doi: 10.1038/s41598-017-12495-0 – volume: 333 start-page: 65 year: 2018 ident: ref_23 article-title: Immunoglobulin G glycosylation in aging and diseases publication-title: Cell. Immunol. doi: 10.1016/j.cellimm.2018.07.009 – volume: 191 start-page: 449 year: 2013 ident: ref_13 article-title: Age dependency of oxygen uptake and related parameters in exercise testing: An expert opinion on reference values suitable for adults publication-title: Lung doi: 10.1007/s00408-013-9483-3 – volume: 13 start-page: 69 year: 2017 ident: ref_22 article-title: Chronic effects of exhausting exercise and overtraining on the immune response: Th1 and Th2 profile publication-title: Motricidade doi: 10.6063/motricidade.10049 – volume: 224 start-page: 110 year: 2019 ident: ref_32 article-title: Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans publication-title: Immunobiology doi: 10.1016/j.imbio.2018.10.002 – volume: 22 start-page: 24 year: 2012 ident: ref_5 article-title: Exercise therapy—The public health message publication-title: Scand. J. Med. Sci. Sport. doi: 10.1111/j.1600-0838.2012.01462.x – volume: 28 start-page: 1 year: 2015 ident: ref_17 article-title: Effects of exercise on immune function publication-title: Sport. Sci. Exch. – volume: 10 start-page: 907 year: 2019 ident: ref_35 article-title: Molecular Pathways MediatingImmunosuppression in Response to Prolonged Intensive Physical Training, Low-Energy Availability, and Intensive Weight Loss publication-title: Front. Immunol. doi: 10.3389/fimmu.2019.00907 – volume: 586 start-page: 37 year: 2017 ident: ref_39 article-title: Comparative Analysis and Validation of Different Steps in Glycomics Studies publication-title: Methods Enzymol. doi: 10.1016/bs.mie.2016.09.027 – volume: 2 start-page: 1143 year: 2012 ident: ref_10 article-title: Lack of exercise is a major cause of chronic diseases publication-title: Compr. Physiol. doi: 10.1002/cphy.c110025 – volume: Volume 4 start-page: 506 year: 2023 ident: ref_27 article-title: N-Glycans and Diabetes publication-title: Encyclopedia of Cell Biology – volume: 380 start-page: 294 year: 2012 ident: ref_4 article-title: The pandemic of physical inactivity: Global action for public health publication-title: Lancet doi: 10.1016/S0140-6736(12)60898-8 – volume: 43 start-page: 1 year: 2009 ident: ref_2 article-title: Physical inactivity: The biggest public health problem of the 21st century publication-title: Br. J. Sport. Med. – ident: ref_7 doi: 10.1371/journal.pone.0168503 – volume: 120 start-page: 5333 year: 2018 ident: ref_19 article-title: Anti-inflammatory response to acute exercise is related with intensity and physical fitness publication-title: J. Cell Biochem. doi: 10.1002/jcb.27810 – volume: 10 start-page: 147 year: 2019 ident: ref_31 article-title: Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity? publication-title: Aging Dis. doi: 10.14336/AD.2018.0326 – volume: 99 start-page: 338 year: 2005 ident: ref_15 article-title: Exercise-induced increase in muscle insulin sensitivity publication-title: J. Appl. Physiol. doi: 10.1152/japplphysiol.00123.2005 – volume: 29 start-page: 817 year: 2019 ident: ref_37 article-title: Comprehensive N-glycosylation analysis of immunoglobulin G from dried blood spots publication-title: Glycobiology doi: 10.1093/glycob/cwz061 – ident: ref_20 doi: 10.3390/antiox7010017 – volume: Volume 4 start-page: 385 year: 2023 ident: ref_28 article-title: Glycans and Cardiovascular Diseases publication-title: Encyclopedia of Cell Biology – volume: 43 start-page: 661 year: 2020 ident: ref_41 article-title: Plasma N-Glycans as Emerging Biomarkers of Cardiometabolic Risk: A Prospective Investigation in the EPIC-Potsdam Cohort Study publication-title: Diabetes Care doi: 10.2337/dc19-1507 |
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