PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)

While neuroinflammation is an evolving concept and the cells involved and their functions are being defined, microglia are understood to be a key cellular mediator of brain injury and repair. The ability to measure microglial activity specifically and noninvasively would be a boon to the study of ne...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 116; H. 5; S. 1686
Hauptverfasser:	Horti, Andrew G, Naik, Ravi, Foss, Catherine A, Minn, Il, Misheneva, Varia, Du, Yong, Wang, Yuchuan, Mathews, William B, Wu, Yunkou, Hall, Andrew, LaCourse, Catherine, Ahn, Hye-Hyun, Nam, Hwanhee, Lesniak, Wojciech G, Valentine, Heather, Pletnikova, Olga, Troncoso, Juan C, Smith, Matthew D, Calabresi, Peter A, Savonenko, Alena V, Dannals, Robert F, Pletnikov, Mikhail V, Pomper, Martin G
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 29.01.2019
Schlagworte:	CSF1R DAM positron-emission tomography [11C]CPPC neuroinflammation
ISSN:	1091-6490, 1091-6490
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