A potential regulatory loop between Lin28B:miR-212 in androgen-independent prostate cancer

Lin28 is a family of RNA binding proteins and microRNA regulators. Two members of this family have been identified: Lin28A and Lin28B, which are encoded by genes localized in different chromosomes but share a high degree of sequence identity. The role of Lin28B in androgen-independent prostate cance...

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Bibliographic Details
Published in:	International journal of oncology Vol. 45; no. 6; pp. 2421 - 2429
Main Authors:	BORREGO-DIAZ, EMMA, POWERS, BENJAMIN C, AZIZOV, VUGAR, LOVELL, SCOTT, REYES, RUBEN, CHAPMAN, BRADLEY, TAWFIK, OSSAMA, McGREGOR, DOUGLAS, DIAZ, FRANCISCO J, WANG, XINKUN, VAN VELDHUIZEN, PETER
Format:	Journal Article
Language:	English
Published:	Greece D.A. Spandidos 01.12.2014 Spandidos Publications Spandidos Publications UK Ltd
Subjects:	Analysis androgen-independent prostate cancer Androgens Androgens - metabolism Binding proteins c-Myc downregulation Cell cycle Cell Line, Tumor Cell Proliferation - genetics Development and progression Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Humans Immunoglobulins Lin28B silencing Lin28B-miR-212-c-Myc pathway Male Metastasis MicroRNA microRNA regulation MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miR-212 Physiological aspects Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Proteins Proto-Oncogene Proteins c-myc - biosynthesis Proto-Oncogene Proteins c-myc - genetics RNA, Messenger - biosynthesis RNA-Binding Proteins - antagonists & inhibitors RNA-Binding Proteins - biosynthesis RNA-Binding Proteins - genetics United States United States > US
ISSN:	1019-6439, 1791-2423, 1791-2423
Online Access:	Get full text
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