The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review

Purpose Pseudomyxoma peritonei (PMP) is a rare clinical malignancy syndrome characterized by the uncontrollable accumulation of copious mucinous ascites in the peritoneal cavity, resulting in “jelly belly”. The mechanism of tumor progression and mucin hypersecretion remains largely unknown, but GNAS...

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Bibliographic Details
Published in:	Journal of cancer research and clinical oncology Vol. 146; no. 9; pp. 2179 - 2188
Main Authors:	Lin, Yu-Lin, Ma, Ru, Li, Yan
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2020 Springer Nature B.V
Subjects:	Ascites Cancer Research Cell proliferation Enzymatic activity Genomes Guanine Guanine nucleotide-binding protein Guanosine triphosphate Hematology Internal Medicine Jelly belly protein Malignancy Medicine Medicine & Public Health Mucin Mutation Oncology Peritoneum Phosphoric acid Protein kinase A Proteins Review – Cancer Research Reviews Secretion Signal transduction Tumors Mucin Signaling pathway Gene mutation Pseudomyxoma peritonei
ISSN:	0171-5216, 1432-1335, 1432-1335
Online Access:	Get full text
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