The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review

Purpose Pseudomyxoma peritonei (PMP) is a rare clinical malignancy syndrome characterized by the uncontrollable accumulation of copious mucinous ascites in the peritoneal cavity, resulting in “jelly belly”. The mechanism of tumor progression and mucin hypersecretion remains largely unknown, but GNAS...

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Veröffentlicht in:	Journal of cancer research and clinical oncology Jg. 146; H. 9; S. 2179 - 2188
Hauptverfasser:	Lin, Yu-Lin, Ma, Ru, Li, Yan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2020 Springer Nature B.V
Schlagworte:	Ascites Cancer Research Cell proliferation Enzymatic activity Genomes Guanine Guanine nucleotide-binding protein Guanosine triphosphate Hematology Internal Medicine Jelly belly protein Malignancy Medicine Medicine & Public Health Mucin Mutation Oncology Peritoneum Phosphoric acid Protein kinase A Proteins Review – Cancer Research Reviews Secretion Signal transduction Tumors Mucin Signaling pathway Gene mutation Pseudomyxoma peritonei
ISSN:	0171-5216, 1432-1335, 1432-1335
Online-Zugang:	Volltext
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