Structural and molecular bases of rod photoreceptor morphogenesis and disease

The rod cell has an extraordinarily specialized structure that allows it to carry out its unique function of detecting individual photons of light. Both the structural features of the rod and the metabolic processes required for highly amplified light detection seem to have rendered the rod especial...

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Bibliographic Details
Published in:	Progress in retinal and eye research Vol. 55; pp. 32 - 51
Main Authors:	Wensel, Theodore G., Zhang, Zhixian, Anastassov, Ivan A., Gilliam, Jared C., He, Feng, Schmid, Michael F., Robichaux, Michael A.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.11.2016
Subjects:	Ciliopathies Cryo-electron tomography Cryoelectron Microscopy - methods Disease mechanisms Humans Membrane Proteins - metabolism Morphogenesis Photoreceptor Retinal degeneration Retinal Diseases - diagnosis Retinal Diseases - metabolism Retinal imaging Retinal Rod Photoreceptor Cells - metabolism Retinal Rod Photoreceptor Cells - ultrastructure Disease mechanisms STED Photoreceptor miniSOG Ciliopathies Cryo-electron tomography SNAP tag STORM Cryo-ET BBS SIM UPR PALM TPR Retinal degeneration SEM BBSome TEM Retinal imaging RP ADRP
ISSN:	1350-9462, 1873-1635
Online Access:	Get full text
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