Pathological α-synuclein distribution in subjects with coincident Alzheimer’s and Lewy body pathology

We investigated the distribution patterns of Lewy body-related pathology (LRP) and the effect of coincident Alzheimer disease (AD) pathology using a data-driven clustering approach that identified groups with different LRP pathology distributions without any diagnostic or researcher’s input in two c...

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Bibliographic Details
Published in:	Acta neuropathologica Vol. 131; no. 3; pp. 393 - 409
Main Authors:	Toledo, Jon B., Gopal, Pallavi, Raible, Kevin, Irwin, David J., Brettschneider, Johannes, Sedor, Samantha, Waits, Kayla, Boluda, Susana, Grossman, Murray, Van Deerlin, Vivianna M., Lee, Edward B., Arnold, Steven E., Duda, John E., Hurtig, Howard, Lee, Virginia M.-Y., Adler, Charles H., Beach, Thomas G., Trojanowski, John Q.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2016
Subjects:	Aged Aged, 80 and over alpha-Synuclein - analysis Alzheimer Disease - complications Alzheimer Disease - pathology Cluster Analysis Female Humans Lewy Bodies - pathology Lewy Body Disease - complications Lewy Body Disease - pathology Male Medicine Medicine & Public Health Neurosciences Original Paper Parkinson Disease - complications Parkinson Disease - pathology Pathology Parkinson disease Diagnosis Alzheimer disease Neuropathology Classification Dementia with Lewy bodies
ISSN:	0001-6322, 1432-0533
Online Access:	Get full text
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