Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment

Background The tumor microenvironment (TME) has been shown to strongly influence treatment outcome for cancer patients in various indications and to influence the overall survival. However, the cells forming the TME in gastric cancer have not been extensively characterized. Results We combine bulk a...

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Veröffentlicht in:	Genome Biology Jg. 23; H. 1; S. 265
Hauptverfasser:	Kang, Boxi, Camps, Jordi, Fan, Biao, Jiang, Hongpeng, Ibrahim, Mahmoud M., Hu, Xueda, Qin, Shishang, Kirchhoff, Dennis, Chiang, Derek Y., Wang, Shan, Ye, Yingjiang, Shen, Zhanlong, Bu, Zhaode, Zhang, Zemin, Roider, Helge G.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 22.12.2022 BMC
Schlagworte:	Animal Genetics and Genomics Bioinformatics biomarkers Biomedical and Life Sciences Endothelial Cells Evolutionary Biology fibroblasts Gastric cancer Gene Expression Profiling genome Human Genetics Humans immunosuppression Life Sciences macrophages Microbial Genetics and Genomics patients Plant Genetics and Genomics prognosis RNA Single-Cell Analysis Single-cell RNA transcriptomics stomach stomach neoplasms Stomach Neoplasms - genetics therapeutics transcription (genetics) Transcriptome Tumor Microenvironment Single-cell RNA transcriptomics Tumor microenvironment Gastric cancer
ISSN:	1474-760X, 1474-7596, 1474-760X
Online-Zugang:	Volltext
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