Dicer functions transcriptionally and posttranscriptionally in a multilayer antiviral defense

In antiviral RNA interference (RNAi), Dicer plays a primary role in processing double-stranded RNA (dsRNA) molecules into small-interfering RNAs (siRNAs) that guide Argonaute effectors to posttranscriptional suppression of target viral genes. Here, we show a distinct role for Dicer in the siRNA-inde...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 116; no. 6; p. 2274
Main Authors:	Andika, Ida Bagus, Kondo, Hideki, Suzuki, Nobuhiro
Format:	Journal Article
Language:	English
Published:	United States 05.02.2019
Subjects:	Ascomycota - genetics Ascomycota - metabolism Ascomycota - virology Disease Resistance - genetics Disease Resistance - immunology Fungal Proteins - genetics Fungal Proteins - metabolism Gene Expression Regulation, Fungal Host-Pathogen Interactions - genetics Mutation Phenotype Ribonuclease III - genetics Ribonuclease III - metabolism RNA Processing, Post-Transcriptional Transcription, Genetic Virus Diseases - genetics Virus Diseases - virology Viruses Cryphonectria parasitica fungal virus RNA silencing antiviral defense SAGA
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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