Carboxypeptidase U (TAFIa): a metallocarboxypeptidase with a distinct role in haemostasis and a possible risk factor for thrombotic disease

Since the discovery of Carboxypeptidase U (CPU) in 1988, considerable information has been gathered about its biochemistry and function in physiological and pathophysiological circumstances. A variety of tools such as assays to measure proCPU and CPU, antibodies raised against (pro)CPU, selective CP...

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Bibliographic Details
Published in:	Thrombosis and haemostasis Vol. 94; no. 3; p. 471
Main Authors:	Leurs, Judith, Hendriks, Dirk
Format:	Journal Article
Language:	English
Published:	Germany 01.09.2005
Subjects:	3-Mercaptopropionic Acid - analogs & derivatives 3-Mercaptopropionic Acid - pharmacology 3-Mercaptopropionic Acid - therapeutic use Animals Blood Platelets - metabolism Carboxypeptidase B2 - antagonists & inhibitors Carboxypeptidase B2 - blood Carboxypeptidase B2 - physiology Enzyme Stability Fibrinolysin - metabolism Hemostasis - physiology Humans Liver - metabolism Mice Mice, Knockout Polymorphism, Genetic Protein Denaturation Risk Factors Succinates - pharmacology Succinates - therapeutic use Thrombin - metabolism Thrombosis - drug therapy Thrombosis - etiology Thrombosis - physiopathology
ISSN:	0340-6245
Online Access:	Get more information
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