WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs

WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of...

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Bibliographic Details
Published in:Bioinformatics (Oxford, England) Vol. 33; no. 19; pp. 3113 - 3114
Main Authors: Galiez, Clovis, Siebert, Matthias, Enault, François, Vincent, Jonathan, Söding, Johannes
Format: Journal Article
Language:English
Published: England Oxford University Press (OUP) 01.10.2017
Oxford University Press
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ISSN:1367-4803, 1367-4811, 1367-4811
Online Access:Get full text
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Summary:WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies. OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/wish. clovis.galiez@mpibpc.mpg.de or soeding@mpibpc.mpg.de. Supplementary data are available at Bioinformatics online.
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PMCID: PMC5870724
ISSN:1367-4803
1367-4811
1367-4811
DOI:10.1093/bioinformatics/btx383