Irradiation at Ultra-High (FLASH) Dose Rates Reduces Acute Normal Tissue Toxicity in the Mouse Gastrointestinal System

Preclinical studies using ultra-high dose rate (FLASH) irradiation have demonstrated reduced normal tissue toxicity compared with conventional dose rate (CONV) irradiation, although this finding is not universal. We investigated the effect of temporal pulse structure and average dose rate of FLASH c...

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Bibliographic Details
Published in:	International journal of radiation oncology, biology, physics Vol. 111; no. 5; p. 1250
Main Authors:	Ruan, Jia-Ling, Lee, Carl, Wouters, Shari, Tullis, Iain D C, Verslegers, Mieke, Mysara, Mohamed, Then, Chee Kin, Smart, Sean C, Hill, Mark A, Muschel, Ruth J, Giaccia, Amato J, Vojnovic, Borivoj, Kiltie, Anne E, Petersson, Kristoffer
Format:	Journal Article
Language:	English
Published:	United States 01.12.2021
Subjects:	Animals Gastrointestinal Tract Mice Mice, Inbred C3H Particle Accelerators Radiotherapy Dosage RNA, Ribosomal, 16S
ISSN:	1879-355X, 1879-355X
Online Access:	Get more information
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