CircRNA: a novel type of biomarker for cancer

Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5′–3′ polarity and contain no polyA tail. CircRNAs also possess relatively jarless framework and are highly tissue-specific expressed in the eukaryotic transcriptome....

Full description

Saved in:

Bibliographic Details
Published in:	Breast cancer (Tokyo, Japan) Vol. 25; no. 1; pp. 1 - 7
Main Authors:	Zhang, He-da, Jiang, Lin-hong, Sun, Da-wei, Hou, Jun-chen, Ji, Zhen-ling
Format:	Journal Article
Language:	English
Published:	Tokyo Springer Japan 01.01.2018 Springer
Subjects:	Animals Biomarkers - analysis Blood circulation disorders Breast Neoplasms - diagnosis Breast Neoplasms - genetics Cancer Cancer Research Cells Colorectal cancer Female Genes Genetic aspects Genetic transcription Health aspects Humans Medicine Medicine & Public Health MicroRNA Oncology Osteoarthritis Review Article RNA - genetics RNA, Long Noncoding - genetics Surgery Surgical Oncology Circular RNA Biomarker MicroRNA Cancer
ISSN:	1340-6868, 1880-4233, 1880-4233
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5′–3′ polarity and contain no polyA tail. CircRNAs also possess relatively jarless framework and are highly tissue-specific expressed in the eukaryotic transcriptome. Emerging evidences have discovered that thousands of endogenous circRNAs are present in mammalian cells and they mediate gene expression at the transcriptional or post-transcriptional level by binding to microRNAs or other molecules and then inhibit their function. Similarly, increasing evidence indicates that circRNAs may play a role in the development of several types of diseases, including atherosclerotic vascular disease risk, neurological disorders, prion diseases, osteoarthritis and diabetes. Furthermore, circRNAs exhibit aberrant expression in multiform types of cancer, including colorectal cancer, hepatocellular carcinoma and pancreatic ductal adenocarcinoma. And based on the function of circRNAs in cancer, we believe that circRNAs may serve as diagnostic or tumor promising biomarkers. Moreover, it will provide a new therapeutic target for the treatment of cancer.
AbstractList	Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5'-3' polarity and contain no polyA tail. CircRNAs also possess relatively jarless framework and are highly tissue-specific expressed in the eukaryotic transcriptome. Emerging evidences have discovered that thousands of endogenous circRNAs are present in mammalian cells and they mediate gene expression at the transcriptional or post-transcriptional level by binding to microRNAs or other molecules and then inhibit their function. Similarly, increasing evidence indicates that circRNAs may play a role in the development of several types of diseases, including atherosclerotic vascular disease risk, neurological disorders, prion diseases, osteoarthritis and diabetes. Furthermore, circRNAs exhibit aberrant expression in multiform types of cancer, including colorectal cancer, hepatocellular carcinoma and pancreatic ductal adenocarcinoma. And based on the function of circRNAs in cancer, we believe that circRNAs may serve as diagnostic or tumor promising biomarkers. Moreover, it will provide a new therapeutic target for the treatment of cancer. Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5'-3' polarity and contain no polyA tail. CircRNAs also possess relatively jarless framework and are highly tissue-specific expressed in the eukaryotic transcriptome. Emerging evidences have discovered that thousands of endogenous circRNAs are present in mammalian cells and they mediate gene expression at the transcriptional or post-transcriptional level by binding to microRNAs or other molecules and then inhibit their function. Similarly, increasing evidence indicates that circRNAs may play a role in the development of several types of diseases, including atherosclerotic vascular disease risk, neurological disorders, prion diseases, osteoarthritis and diabetes. Furthermore, circRNAs exhibit aberrant expression in multiform types of cancer, including colorectal cancer, hepatocellular carcinoma and pancreatic ductal adenocarcinoma. And based on the function of circRNAs in cancer, we believe that circRNAs may serve as diagnostic or tumor promising biomarkers. Moreover, it will provide a new therapeutic target for the treatment of cancer.Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5'-3' polarity and contain no polyA tail. CircRNAs also possess relatively jarless framework and are highly tissue-specific expressed in the eukaryotic transcriptome. Emerging evidences have discovered that thousands of endogenous circRNAs are present in mammalian cells and they mediate gene expression at the transcriptional or post-transcriptional level by binding to microRNAs or other molecules and then inhibit their function. Similarly, increasing evidence indicates that circRNAs may play a role in the development of several types of diseases, including atherosclerotic vascular disease risk, neurological disorders, prion diseases, osteoarthritis and diabetes. Furthermore, circRNAs exhibit aberrant expression in multiform types of cancer, including colorectal cancer, hepatocellular carcinoma and pancreatic ductal adenocarcinoma. And based on the function of circRNAs in cancer, we believe that circRNAs may serve as diagnostic or tumor promising biomarkers. Moreover, it will provide a new therapeutic target for the treatment of cancer.
Audience	Academic
Author	Ji, Zhen-ling Sun, Da-wei Hou, Jun-chen Jiang, Lin-hong Zhang, He-da
Author_xml	– sequence: 1 givenname: He-da surname: Zhang fullname: Zhang, He-da organization: Department of General Surgery, School of Medicine, Southeast University, Department of General Surgery, Institute for Minimally Invasive Surgery, Zhongda Hospital Southeast University – sequence: 2 givenname: Lin-hong surname: Jiang fullname: Jiang, Lin-hong organization: Xuzhou Medical University – sequence: 3 givenname: Da-wei surname: Sun fullname: Sun, Da-wei organization: Department of General Surgery, Nanjing Medical University Affiliated Cancer Hospital, Cancer Institute of Jiangsu Province – sequence: 4 givenname: Jun-chen surname: Hou fullname: Hou, Jun-chen organization: Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University – sequence: 5 givenname: Zhen-ling surname: Ji fullname: Ji, Zhen-ling email: zhenlingji11@hotmail.com, zhanghedazhd@163.com organization: Department of General Surgery, School of Medicine, Southeast University, Department of General Surgery, Institute for Minimally Invasive Surgery, Zhongda Hospital Southeast University
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/28721656$$D View this record in MEDLINE/PubMed
BookMark	eNp9kUuLFDEUhYOMOA_9AW6kwI2bjHlVHu6axsfAoCC6DqnkZshYnbRJtTD_3jQ1Cg4yZJEQvnPu5ZxzdJJLBoReUnJJCVFvG2VMM0yowkQZjs0TdEa1Jlgwzk_6mwuCpZb6FJ23dkuI4IrIZ-iUacWoHOUZwttU_dfPm3eDG3L5BfOw3O1hKHGYUtm5-gPqEEsdvMse6nP0NLq5wYv7-wJ9__D-2_YTvv7y8Wq7ucZ-FGLBjkgHghtBTNBEawV6pFE6Ic0UIpvG4FQMMBpCQXNFWQhG8YlIFeREvOIX6M3qu6_l5wHaYnepeZhnl6EcmqWGkW6v6NjR1yt642awKceyVOePuN10Z6aMMaJTl_-h-gmwS76nGlP__0fw6n6Dw7SDYPc19TTu7J_kOkBXwNfSWoX4F6HEHtuxazu2t2OP7VjTNeqBxqfFLankvk2aH1WyVdn6lHwD1d6WQ829g0dEvwHfA56e
CitedBy_id	crossref_primary_10_1016_j_aohep_2022_100722 crossref_primary_10_1016_j_gene_2023_147247 crossref_primary_10_1155_2022_9461054 crossref_primary_10_2147_OTT_S286820 crossref_primary_10_1016_j_tiv_2021_105271 crossref_primary_10_1016_j_prp_2019_152507 crossref_primary_10_1038_s41598_025_12492_8 crossref_primary_10_3390_cancers15072068 crossref_primary_10_1038_s41420_021_00577_y crossref_primary_10_1016_j_prp_2024_155476 crossref_primary_10_1515_med_2023_0632 crossref_primary_10_1007_s10528_023_10407_8 crossref_primary_10_1038_s41419_021_03459_4 crossref_primary_10_1016_j_lfs_2024_122809 crossref_primary_10_1016_j_bbrc_2018_01_126 crossref_primary_10_1016_j_microc_2025_113257 crossref_primary_10_2147_CMAR_S232260 crossref_primary_10_2147_CMAR_S257441 crossref_primary_10_1038_s41419_022_05536_8 crossref_primary_10_3389_fgene_2021_779195 crossref_primary_10_1016_j_jds_2022_05_012 crossref_primary_10_1016_j_ecoenv_2023_115778 crossref_primary_10_1007_s10528_022_10201_y crossref_primary_10_1093_bib_bbaa274 crossref_primary_10_1109_TCBB_2024_3355093 crossref_primary_10_1186_s13018_021_02323_7 crossref_primary_10_2174_0115748936346422240930081839 crossref_primary_10_3390_ijms25031897 crossref_primary_10_1002_bab_2172 crossref_primary_10_1186_s13046_021_02029_y crossref_primary_10_1038_s41419_022_04811_y crossref_primary_10_1016_j_trim_2022_101641 crossref_primary_10_3389_fonc_2020_545460 crossref_primary_10_3892_ijo_2018_4265 crossref_primary_10_1002_jcla_23856 crossref_primary_10_1002_jbt_23705 crossref_primary_10_3389_fonc_2019_00502 crossref_primary_10_1007_s12640_021_00464_5 crossref_primary_10_1016_j_prp_2022_153871 crossref_primary_10_1002_jbt_23833 crossref_primary_10_1007_s12195_021_00717_5 crossref_primary_10_1134_S000629792405016X crossref_primary_10_3233_CBM_190812 crossref_primary_10_3390_cells9020276 crossref_primary_10_3389_fonc_2023_1122982 crossref_primary_10_2147_CMAR_S244024 crossref_primary_10_1016_j_canlet_2022_215975 crossref_primary_10_1016_j_mcp_2022_101829 crossref_primary_10_3389_fphar_2022_968776 crossref_primary_10_3389_fonc_2021_621353 crossref_primary_10_1016_j_cancergen_2019_11_001 crossref_primary_10_1080_10495398_2022_2124165 crossref_primary_10_1016_j_genrep_2024_101969 crossref_primary_10_1186_s13018_021_02248_1 crossref_primary_10_1016_j_bbrep_2025_101935 crossref_primary_10_1038_s41420_021_00420_4 crossref_primary_10_1080_21655979_2022_2084257 crossref_primary_10_2147_IJN_S279258 crossref_primary_10_3390_ijms21010258 crossref_primary_10_1002_kjm2_12478 crossref_primary_10_1016_j_advms_2023_10_003 crossref_primary_10_1007_s10528_022_10224_5 crossref_primary_10_1016_j_phymed_2020_153168 crossref_primary_10_2147_CMAR_S280307 crossref_primary_10_1016_j_acthis_2021_151745 crossref_primary_10_1002_adfm_202401547 crossref_primary_10_1016_j_clinsp_2022_100018 crossref_primary_10_1097_CAD_0000000000000990 crossref_primary_10_1111_cas_14131 crossref_primary_10_1007_s00404_022_06481_9 crossref_primary_10_1080_15384101_2019_1690883 crossref_primary_10_1016_j_arr_2020_101058 crossref_primary_10_1111_1759_7714_13529 crossref_primary_10_1186_s40164_022_00342_6 crossref_primary_10_3389_fimmu_2022_951135 crossref_primary_10_1186_s12859_020_03942_3 crossref_primary_10_1016_j_compbiomed_2023_107077 crossref_primary_10_3390_genes13050846 crossref_primary_10_1016_j_pharmthera_2022_108123 crossref_primary_10_1080_15384101_2018_1556058 crossref_primary_10_1097_MD_0000000000019171 crossref_primary_10_1186_s12943_019_1041_z crossref_primary_10_1016_j_gene_2024_148817 crossref_primary_10_1038_s41419_022_05286_7 crossref_primary_10_1155_2022_2488139 crossref_primary_10_1002_iub_2419 crossref_primary_10_1097_FJC_0000000000000879 crossref_primary_10_1080_15384101_2023_2222519 crossref_primary_10_2147_CMAR_S314882 crossref_primary_10_1007_s12672_024_00933_1 crossref_primary_10_1177_09603271231155093 crossref_primary_10_3389_fgene_2023_1050783 crossref_primary_10_3390_ijms23126822 crossref_primary_10_1016_j_heliyon_2023_e19807 crossref_primary_10_1007_s11011_023_01184_9 crossref_primary_10_1002_jcla_23642 crossref_primary_10_1111_1759_7714_14943 crossref_primary_10_1007_s00018_025_05653_5 crossref_primary_10_1177_0300891620941940 crossref_primary_10_1007_s11010_021_04160_y crossref_primary_10_1016_j_omtm_2020_05_027 crossref_primary_10_1038_s41420_021_00771_y crossref_primary_10_1016_j_jbo_2021_100347 crossref_primary_10_1111_cns_14735 crossref_primary_10_1002_cam4_3043 crossref_primary_10_1080_10799893_2021_1910706 crossref_primary_10_1016_j_abb_2018_04_017 crossref_primary_10_1016_j_cca_2019_07_004 crossref_primary_10_1016_j_trim_2022_101685 crossref_primary_10_1186_s12943_020_01152_2 crossref_primary_10_1186_s41544_019_0046_5 crossref_primary_10_1080_15548627_2021_1917131 crossref_primary_10_1080_21655979_2021_1923259 crossref_primary_10_2147_IJGM_S272996 crossref_primary_10_1016_j_envint_2024_108515 crossref_primary_10_1016_j_exer_2019_03_017 crossref_primary_10_1111_jvh_13917 crossref_primary_10_1016_j_clim_2022_109007 crossref_primary_10_1002_jmr_2932 crossref_primary_10_1007_s11011_022_00915_8 crossref_primary_10_1111_1759_7714_14803 crossref_primary_10_1186_s12935_020_01349_x crossref_primary_10_1155_2021_7608178 crossref_primary_10_1186_s12935_020_01293_w crossref_primary_10_1002_term_3189 crossref_primary_10_1016_j_pharmthera_2022_108156 crossref_primary_10_1186_s12943_020_01298_z crossref_primary_10_4251_wjgo_v12_i11_1272 crossref_primary_10_3389_fcell_2020_00714 crossref_primary_10_3389_fmolb_2021_649100 crossref_primary_10_1007_s10528_022_10245_0 crossref_primary_10_3892_mmr_2020_11069 crossref_primary_10_1186_s12943_022_01560_6 crossref_primary_10_1007_s10495_022_01743_y crossref_primary_10_1177_1559325819837795 crossref_primary_10_1007_s12032_023_02194_4 crossref_primary_10_1093_bib_bbab342 crossref_primary_10_1515_biol_2021_0009 crossref_primary_10_1016_j_archoralbio_2022_105567 crossref_primary_10_3389_fonc_2022_862602 crossref_primary_10_1155_2021_5510869 crossref_primary_10_2147_CMAR_S311242 crossref_primary_10_1016_j_thromres_2020_11_032 crossref_primary_10_1111_1759_7714_13603 crossref_primary_10_1002_kjm2_12686 crossref_primary_10_1002_1878_0261_12862 crossref_primary_10_1002_kjm2_12443 crossref_primary_10_1002_med_21950 crossref_primary_10_1007_s12204_024_2575_9 crossref_primary_10_1186_s12967_021_03045_4 crossref_primary_10_1002_ags3_12665 crossref_primary_10_1186_s12943_024_02120_w crossref_primary_10_3389_fgene_2020_626492 crossref_primary_10_1016_j_bbrc_2025_152655 crossref_primary_10_1093_bib_bbac613 crossref_primary_10_1093_jb_mvaa093 crossref_primary_10_1007_s12079_022_00696_w crossref_primary_10_1007_s12668_025_01958_8 crossref_primary_10_2147_OTT_S280434 crossref_primary_10_1002_med_21948 crossref_primary_10_5761_atcs_oa_22_00090 crossref_primary_10_1016_j_placenta_2020_10_010 crossref_primary_10_1111_1759_7714_13032 crossref_primary_10_1016_j_bbrc_2021_06_009 crossref_primary_10_1186_s13765_022_00729_3 crossref_primary_10_1186_s12872_021_02012_7 crossref_primary_10_1186_s13046_020_01642_7 crossref_primary_10_1007_s11154_021_09646_0 crossref_primary_10_3389_fneur_2022_931435 crossref_primary_10_1007_s10528_023_10611_6 crossref_primary_10_1186_s12935_020_01241_8 crossref_primary_10_1016_j_ymthe_2020_01_010 crossref_primary_10_3390_cancers13225748 crossref_primary_10_1016_j_bbrc_2019_05_158 crossref_primary_10_1186_s12864_020_07129_1 crossref_primary_10_1186_s13048_021_00916_8 crossref_primary_10_3390_cells12141916 crossref_primary_10_1111_jcmm_13676 crossref_primary_10_1111_jcmm_14400 crossref_primary_10_3892_ol_2021_12965 crossref_primary_10_1007_s10528_022_10256_x crossref_primary_10_1177_17085381211016150 crossref_primary_10_1007_s12031_020_01698_2 crossref_primary_10_1113_JP284086 crossref_primary_10_1016_j_gene_2020_144798 crossref_primary_10_1016_j_pharmthera_2024_108711 crossref_primary_10_1111_1759_7714_14221 crossref_primary_10_1016_j_cca_2020_11_015 crossref_primary_10_1016_j_omtn_2019_12_028 crossref_primary_10_2147_OTT_S233000 crossref_primary_10_3389_fcvm_2022_1074835 crossref_primary_10_1128_MCB_00517_20 crossref_primary_10_1080_07853890_2023_2185289 crossref_primary_10_1002_em_22506 crossref_primary_10_1016_j_lfs_2020_118376 crossref_primary_10_1007_s00210_023_02663_7 crossref_primary_10_1186_s12935_021_01984_y crossref_primary_10_1038_s41419_019_1890_9 crossref_primary_10_1186_s12885_021_09052_4 crossref_primary_10_1038_s41598_025_15333_w crossref_primary_10_1002_cac2_12380 crossref_primary_10_1177_1533033820983302 crossref_primary_10_3389_fcell_2020_00230 crossref_primary_10_1007_s12035_025_04863_z crossref_primary_10_1007_s12307_019_00230_4 crossref_primary_10_1080_21655979_2021_1935064 crossref_primary_10_2174_1381612827666210303141416 crossref_primary_10_1186_s12885_022_09323_8 crossref_primary_10_1016_j_bbrc_2021_09_085 crossref_primary_10_1016_j_intimp_2022_108740 crossref_primary_10_3892_etm_2023_12082 crossref_primary_10_1155_2021_6659695 crossref_primary_10_1038_s41420_021_00461_9 crossref_primary_10_1186_s12935_020_1120_7 crossref_primary_10_1016_j_prp_2023_154730 crossref_primary_10_1007_s10792_021_02067_7 crossref_primary_10_1080_21655979_2021_1914470 crossref_primary_10_3892_mmr_2021_12401 crossref_primary_10_1016_j_bios_2022_114258 crossref_primary_10_1016_j_molstruc_2023_137050 crossref_primary_10_3389_fcvm_2022_850991 crossref_primary_10_1186_s12935_025_03815_w crossref_primary_10_1155_2020_2862701 crossref_primary_10_1016_j_prp_2023_154609 crossref_primary_10_1016_j_repbio_2022_100637 crossref_primary_10_3389_fonc_2020_01526 crossref_primary_10_1016_j_omto_2022_02_020 crossref_primary_10_1111_jcmm_15414 crossref_primary_10_3389_fimmu_2025_1563655 crossref_primary_10_1016_j_canlet_2024_216794 crossref_primary_10_1038_s41419_022_04677_0 crossref_primary_10_1111_1759_7714_14408 crossref_primary_10_1016_j_clbc_2021_08_009 crossref_primary_10_1109_TCBB_2023_3272400 crossref_primary_10_1016_j_bcp_2021_114469 crossref_primary_10_1186_s13048_020_00664_1 crossref_primary_10_1007_s10863_021_09876_6 crossref_primary_10_1111_aos_14585 crossref_primary_10_1016_j_isci_2024_110861 crossref_primary_10_3892_mmr_2021_12426 crossref_primary_10_2147_OTT_S299190 crossref_primary_10_1007_s12265_022_10247_8 crossref_primary_10_1155_2022_3902832 crossref_primary_10_1515_med_2023_0803 crossref_primary_10_3390_ijms22105182 crossref_primary_10_1016_j_omto_2022_02_011 crossref_primary_10_1155_2022_4288474 crossref_primary_10_1016_j_domaniend_2019_106401 crossref_primary_10_1016_j_bbrc_2024_151236 crossref_primary_10_3892_ol_2018_9357 crossref_primary_10_1186_s12935_020_01492_5 crossref_primary_10_1080_21655979_2022_2036905 crossref_primary_10_1111_1759_7714_14773 crossref_primary_10_1155_2021_6614591 crossref_primary_10_1080_02648725_2023_2199243 crossref_primary_10_1186_s13062_024_00509_7 crossref_primary_10_3389_fonc_2025_1441384 crossref_primary_10_3892_mmr_2021_12338 crossref_primary_10_1111_1759_7714_15163 crossref_primary_10_1111_1759_7714_14191 crossref_primary_10_2147_OTT_S243533 crossref_primary_10_1016_j_jbi_2022_104231 crossref_primary_10_1080_15384047_2023_2218514 crossref_primary_10_3389_fphys_2020_01010 crossref_primary_10_1016_j_biopha_2019_109619 crossref_primary_10_1002_jgm_3263 crossref_primary_10_1097_CAD_0000000000001037 crossref_primary_10_3390_ijms20040919 crossref_primary_10_1186_s12943_024_02052_5 crossref_primary_10_1016_j_bcmd_2020_102506 crossref_primary_10_1002_cbin_11906 crossref_primary_10_1111_1759_7714_14085 crossref_primary_10_1016_j_canlet_2021_02_010 crossref_primary_10_1016_j_pbiomolbio_2019_11_009 crossref_primary_10_7717_peerj_17089 crossref_primary_10_1177_17246008211043128 crossref_primary_10_1016_j_omtn_2021_04_006 crossref_primary_10_1109_TCBB_2024_3488281 crossref_primary_10_1155_2022_5075615 crossref_primary_10_1002_jcb_29446 crossref_primary_10_1089_cbr_2020_3739 crossref_primary_10_1007_s10528_025_11051_0 crossref_primary_10_3390_macromol4020009 crossref_primary_10_3389_fonc_2021_606764 crossref_primary_10_1007_s10529_020_03059_w crossref_primary_10_1080_21655979_2021_1965697 crossref_primary_10_3389_fonc_2022_801842 crossref_primary_10_1016_j_omtn_2019_06_026 crossref_primary_10_1080_15384101_2021_1962633 crossref_primary_10_1007_s12265_020_09976_5 crossref_primary_10_1016_j_bbrc_2018_06_045 crossref_primary_10_1111_jcmm_15572 crossref_primary_10_2147_CMAR_S231872 crossref_primary_10_3389_fgene_2020_00403 crossref_primary_10_1155_2021_6633289 crossref_primary_10_1186_s12957_020_02033_0 crossref_primary_10_1186_s12943_019_1081_4 crossref_primary_10_1038_s41598_019_57404_9 crossref_primary_10_1186_s12890_022_02209_2 crossref_primary_10_3390_biomedicines11051316 crossref_primary_10_1016_j_talanta_2021_123066 crossref_primary_10_1080_21691401_2018_1553787 crossref_primary_10_3389_fonc_2021_649242 crossref_primary_10_1093_burnst_tkac025 crossref_primary_10_1155_2020_6075902 crossref_primary_10_3892_mmr_2019_10811 crossref_primary_10_1186_s12935_020_01562_8 crossref_primary_10_3389_fonc_2021_780744 crossref_primary_10_1016_j_knosys_2024_111622 crossref_primary_10_1016_j_bbrc_2018_05_114 crossref_primary_10_1007_s12672_023_00679_2 crossref_primary_10_1111_cpr_12614 crossref_primary_10_3390_cells13171483 crossref_primary_10_1002_jbt_70205 crossref_primary_10_1007_s10528_021_10102_6 crossref_primary_10_1016_j_canlet_2020_01_022 crossref_primary_10_1111_apm_13321 crossref_primary_10_1186_s12957_021_02184_8 crossref_primary_10_1097_CAD_0000000000001076 crossref_primary_10_1016_j_gene_2020_144971 crossref_primary_10_1007_s11033_023_08791_w crossref_primary_10_1080_15384101_2020_1824717 crossref_primary_10_3389_fgene_2021_652995 crossref_primary_10_1097_MPA_0000000000002205 crossref_primary_10_1186_s40709_021_00154_5 crossref_primary_10_3390_ani10081347 crossref_primary_10_1155_2021_9980459 crossref_primary_10_1007_s43032_022_00920_3 crossref_primary_10_1155_2022_2521951 crossref_primary_10_1016_j_jad_2020_05_109 crossref_primary_10_1186_s12935_020_01168_0 crossref_primary_10_1186_s41065_025_00449_w crossref_primary_10_1186_s11658_021_00284_7 crossref_primary_10_1097_FJC_0000000000001055 crossref_primary_10_1016_j_cellsig_2020_109603 crossref_primary_10_1186_s12935_020_01399_1 crossref_primary_10_1093_nar_gkab1036 crossref_primary_10_3389_fonc_2020_00150 crossref_primary_10_3390_cells10071620 crossref_primary_10_3389_fgene_2020_00892 crossref_primary_10_1186_s12935_020_01451_0 crossref_primary_10_1186_s12967_024_05745_z crossref_primary_10_2147_CMAR_S302084 crossref_primary_10_1002_jcp_26764 crossref_primary_10_1016_j_bbrc_2019_07_065 crossref_primary_10_3389_fonc_2023_1174577 crossref_primary_10_1007_s13577_022_00835_w crossref_primary_10_3390_ijms232315204 crossref_primary_10_1080_15384101_2021_1941612 crossref_primary_10_1002_jbt_23118 crossref_primary_10_1007_s00109_017_1603_8 crossref_primary_10_1002_tox_23982 crossref_primary_10_1186_s10020_021_00330_2 crossref_primary_10_1111_cas_15820 crossref_primary_10_1186_s13046_020_01697_6 crossref_primary_10_1093_labmed_lmab062 crossref_primary_10_1128_MCB_00100_21 crossref_primary_10_3390_ijms222413607 crossref_primary_10_1007_s10528_021_10092_5 crossref_primary_10_3390_biomedicines9111590 crossref_primary_10_1080_08916934_2021_2023863 crossref_primary_10_1080_21655979_2021_1916276 crossref_primary_10_1186_s12935_020_1162_x crossref_primary_10_1016_j_envres_2023_116007 crossref_primary_10_3892_ol_2020_11507 crossref_primary_10_1007_s13755_024_00318_2 crossref_primary_10_1080_21655979_2021_1983974 crossref_primary_10_1007_s11064_020_03139_3 crossref_primary_10_1007_s10528_022_10207_6 crossref_primary_10_3389_fgene_2021_625019 crossref_primary_10_1177_09287329241291432 crossref_primary_10_1080_21655979_2021_1981798 crossref_primary_10_1515_med_2019_0097 crossref_primary_10_1186_s12943_025_02239_4 crossref_primary_10_1038_s41598_025_05486_z crossref_primary_10_3389_fmed_2021_615417 crossref_primary_10_3389_fonc_2020_01104 crossref_primary_10_1038_s41598_021_01203_8 crossref_primary_10_1111_1759_7714_14377 crossref_primary_10_1186_s12859_023_05352_7 crossref_primary_10_1002_kjm2_12404 crossref_primary_10_1038_s41598_020_79781_2 crossref_primary_10_1177_09603271221141689 crossref_primary_10_2147_OTT_S217087 crossref_primary_10_1007_s12265_023_10383_9 crossref_primary_10_1159_000516870 crossref_primary_10_2217_bmm_2019_0143 crossref_primary_10_1016_j_semcancer_2020_07_003 crossref_primary_10_1007_s10637_019_00884_3 crossref_primary_10_1038_s41598_021_98470_2 crossref_primary_10_2147_OTT_S246092 crossref_primary_10_3892_etm_2021_10589 crossref_primary_10_1016_j_omtn_2020_01_031 crossref_primary_10_1080_15384101_2021_1954758 crossref_primary_10_1155_2022_6062236 crossref_primary_10_1016_j_gene_2020_145068 crossref_primary_10_1093_brain_awae135 crossref_primary_10_1016_j_pharmthera_2022_108188 crossref_primary_10_2147_CMAR_S272309 crossref_primary_10_3892_etm_2021_10366 crossref_primary_10_1155_2021_9935986 crossref_primary_10_1080_15384101_2022_2075197 crossref_primary_10_1007_s10528_022_10227_2 crossref_primary_10_1093_carcin_bgac053 crossref_primary_10_1016_j_semcancer_2020_11_004 crossref_primary_10_1007_s00109_020_01934_7 crossref_primary_10_1002_jcla_24421 crossref_primary_10_3892_or_2021_8223 crossref_primary_10_1002_cbin_11872 crossref_primary_10_1002_jcla_23575 crossref_primary_10_1186_s11658_022_00364_2 crossref_primary_10_1002_jcla_24304 crossref_primary_10_1016_j_intimp_2024_112909 crossref_primary_10_3389_fphar_2021_633353 crossref_primary_10_1016_j_lfs_2020_118829 crossref_primary_10_1002_jcb_29490 crossref_primary_10_1515_med_2021_0001 crossref_primary_10_1007_s10528_024_10674_z crossref_primary_10_1038_s41419_020_02785_3 crossref_primary_10_2174_0109298673275752231219080500 crossref_primary_10_1186_s43556_020_00004_1 crossref_primary_10_1002_jcb_29014 crossref_primary_10_1038_s41417_024_00830_3 crossref_primary_10_1186_s11658_022_00330_y crossref_primary_10_1111_jcmm_16022 crossref_primary_10_1155_2022_8402732 crossref_primary_10_1186_s13578_019_0355_2 crossref_primary_10_1007_s10620_020_06641_4 crossref_primary_10_1016_j_isci_2025_112858 crossref_primary_10_1007_s11356_022_22094_w crossref_primary_10_2147_OTT_S263655 crossref_primary_10_1080_10495398_2022_2140056 crossref_primary_10_1002_cam4_3703 crossref_primary_10_1155_2019_1684039 crossref_primary_10_1186_s12872_020_01800_x crossref_primary_10_1097_FJC_0000000000000983 crossref_primary_10_1007_s13577_021_00573_5 crossref_primary_10_1016_j_jri_2022_103681 crossref_primary_10_1080_15384101_2021_2020041 crossref_primary_10_1186_s12885_018_4213_0 crossref_primary_10_1186_s12967_023_04238_9 crossref_primary_10_1007_s11010_022_04543_9 crossref_primary_10_1177_0963689720961070 crossref_primary_10_1002_kjm2_12604 crossref_primary_10_1515_med_2021_0269 crossref_primary_10_1186_s11658_023_00448_7 crossref_primary_10_3390_cancers13164185 crossref_primary_10_1007_s10528_024_10672_1 crossref_primary_10_3892_ol_2021_13158 crossref_primary_10_1016_j_heliyon_2024_e27307 crossref_primary_10_3389_fgene_2022_994163 crossref_primary_10_1007_s11427_024_2946_1 crossref_primary_10_1016_j_tranon_2023_101810 crossref_primary_10_3390_cells11213460 crossref_primary_10_1007_s00018_018_2877_x crossref_primary_10_1007_s12539_024_00616_z crossref_primary_10_1016_j_neuroscience_2022_03_035 crossref_primary_10_1007_s43032_022_00925_y crossref_primary_10_2147_CMAR_S251666 crossref_primary_10_1016_j_omto_2021_11_002 crossref_primary_10_1007_s11033_022_07723_4 crossref_primary_10_1007_s11748_023_01960_5 crossref_primary_10_1016_j_gene_2023_147733 crossref_primary_10_1016_j_biopha_2019_109365 crossref_primary_10_3892_mmr_2023_13081 crossref_primary_10_1111_eci_13581 crossref_primary_10_3892_ijmm_2019_4240 crossref_primary_10_1093_jb_mvaa106 crossref_primary_10_1186_s40709_021_00135_8 crossref_primary_10_2147_CMAR_S292074 crossref_primary_10_1177_17246008211073151 crossref_primary_10_3390_ijms25147656 crossref_primary_10_1186_s13046_019_1398_2 crossref_primary_10_3390_ijms24032636 crossref_primary_10_1007_s10528_021_10171_7 crossref_primary_10_1515_med_2022_0604 crossref_primary_10_1038_s41416_024_02612_y crossref_primary_10_2147_OTT_S254735 crossref_primary_10_3389_fgene_2022_1006307 crossref_primary_10_1002_jcla_23252 crossref_primary_10_1016_j_lfs_2020_118622 crossref_primary_10_2217_epi_2018_0002 crossref_primary_10_1002_jcla_23258 crossref_primary_10_1097_CAD_0000000000001347 crossref_primary_10_2147_IJGM_S441861 crossref_primary_10_3389_fonc_2020_549982 crossref_primary_10_12998_wjcc_v9_i34_10400 crossref_primary_10_1186_s12957_021_02373_5 crossref_primary_10_1007_s00436_020_07018_2 crossref_primary_10_1093_bib_bbac289 crossref_primary_10_1007_s10735_022_10061_1 crossref_primary_10_1186_s12859_024_05644_6 crossref_primary_10_1155_2021_9978206 crossref_primary_10_1007_s12539_023_00572_0 crossref_primary_10_2147_CMAR_S256091 crossref_primary_10_1111_jcmm_18137 crossref_primary_10_3389_fgene_2020_00962 crossref_primary_10_3389_fonc_2021_733745 crossref_primary_10_1177_09636897231193066 crossref_primary_10_3389_fonc_2022_939790 crossref_primary_10_1186_s12957_021_02287_2 crossref_primary_10_1097_CAD_0000000000001373 crossref_primary_10_1007_s12257_021_0190_2 crossref_primary_10_1007_s13258_021_01114_y crossref_primary_10_1155_2021_2469691 crossref_primary_10_3389_fmicb_2022_975223 crossref_primary_10_1016_j_biopha_2019_109582 crossref_primary_10_1038_s41419_021_03558_2 crossref_primary_10_3389_fonc_2020_523342 crossref_primary_10_2147_IJGM_S426218 crossref_primary_10_3390_ijms241813981 crossref_primary_10_1016_j_exphem_2022_07_298 crossref_primary_10_1007_s11010_022_04412_5 crossref_primary_10_1016_j_jdiacomp_2025_109042 crossref_primary_10_1111_iwj_13535 crossref_primary_10_2147_OTT_S272294 crossref_primary_10_1002_dmrr_3394 crossref_primary_10_1007_s10142_022_00862_8 crossref_primary_10_1038_s41598_022_26220_z crossref_primary_10_1097_CAD_0000000000001361 crossref_primary_10_1016_j_canlet_2025_217494 crossref_primary_10_1016_j_arr_2021_101390 crossref_primary_10_1186_s13071_020_04047_9 crossref_primary_10_1002_jcla_24008 crossref_primary_10_1007_s12094_023_03173_x
Cites_doi	10.1186/s13059-014-0409-z 10.1006/geno.1997.5122 10.1038/cddis.2014.305 10.3892/or.2014.3519 10.1038/nrc2223 10.1016/j.celrep.2014.10.062 10.1371/journal.pone.0158347 10.1038/srep08057 10.1016/0092-8674(93)90279-Y 10.1038/cr.2015.82 10.1038/srep37982 10.1038/cdd.2016.133 10.3322/caac.20107 10.18632/oncotarget.2044 10.1016/j.cca.2015.02.018 10.1371/journal.pgen.1001233 10.18632/oncotarget.7656 10.1136/jmedgenet-2016-103758 10.1093/nar/gkw027 10.1038/nbt.2890 10.1016/j.canlet.2015.06.003 10.1097/MD.0000000000003811 10.1371/journal.pgen.1003777 10.1038/nature11993 10.1016/j.molcel.2013.08.017 10.1016/S1040-8428(99)00051-7 10.3748/wjg.v22.i29.6610 10.1373/clinchem.2014.230433 10.1007/s13277-015-3199-3 10.1080/15476286.2015.1020271 10.1042/BJ20100859 10.1016/j.molcel.2014.08.019 10.1097/01.sla.0000225126.56483.b3 10.1093/nar/gks247 10.1038/ncomms11215 10.1038/nsmb.2580 10.1136/gutjnl-2013-306627 10.1038/emboj.2013.53 10.1126/science.1064921 10.18632/oncotarget.3469 10.1158/0008-5472.CAN-13-1568 10.1371/journal.pone.0030733 10.1158/0008-5472.CAN-07-6639 10.1038/nature11928 10.1016/j.cell.2014.09.005 10.1016/j.cell.2009.01.002 10.1093/nar/gkl151 10.1038/onc.2011.558 10.1182/blood-2007-02-073957 10.3892/or.2015.3904 10.1038/onc.2015.460 10.1016/j.cell.2014.09.001 10.1261/rna.035667.112 10.1038/emboj.2011.359 10.3233/CBM-150552 10.1016/j.jbiotec.2016.09.011 10.1158/0008-5472.CAN-14-3735 10.1056/NEJMra035010 10.1186/1476-4598-13-124 10.1186/s12967-016-0977-7 10.1038/s41598-016-0007-2 10.1038/nrdp.2016.18 10.3389/fgene.2013.00283 10.1096/fasebj.7.1.7678559 10.1007/s00432-016-2256-7 10.18632/oncotarget.13134
ContentType	Journal Article
Copyright	The Japanese Breast Cancer Society 2017 COPYRIGHT 2018 Springer
Copyright_xml	– notice: The Japanese Breast Cancer Society 2017 – notice: COPYRIGHT 2018 Springer
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8
DOI	10.1007/s12282-017-0793-9
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic
DatabaseTitleList	MEDLINE MEDLINE - Academic
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
EISSN	1880-4233
EndPage	7
ExternalDocumentID	A712279994 28721656 10_1007_s12282_017_0793_9
Genre	Journal Article Review
GroupedDBID	--- -53 -5E -5G -BR -EM -Y2 -~C .86 .VR 06C 06D 0R~ 0VY 1N0 2.D 203 23N 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2WC 30V 4.4 406 408 40D 40E 53G 5GY 5VS 67Z 6NX 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABJNI ABJOX ABKCH ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTKH ABTMW ABULA ABWNU ABXPI ACAOD ACDTI ACGFS ACHSB ACHVE ACHXU ACKNC ACMDZ ACMLO ACOKC ACPIV ACSNA ACUDM ACZOJ ADHHG ADHIR ADINQ ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBWZM BDATZ BGNMA CAG COF CS3 CSCUP DDRTE DIK DNIVK DPUIP DU5 E3Z EBLON EBS EIOEI EJD EMOBN EN4 ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GRRUI H13 HF~ HG5 HG6 HMJXF HRMNR HVGLF HZ~ IAO IEA IHR IKXTQ IMOTQ INH ITC IWAJR IXD I~X I~Z J-C J0Z JBSCW JSF JSH JZLTJ KOV KPH KQ8 LLZTM M4Y MA- N2Q N9A NDZJH NF0 NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OK1 OVD P19 P2P P6G P9S PF0 PT4 PT5 QOK QOR QOS R89 R9I RHV RJT RNI ROL RPX RSV RZJ RZK S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TEORI TKC TR2 TSG TSK TT1 TUC U2A U9L UDS UG4 UOJIU UTJUX UZXMN VC2 VFIZW W48 WK8 YLTOR Z45 Z7U Z82 Z87 Z8O Z8V Z91 ZMTXR ZOVNA ~A9 AAPKM AAYXX ABBRH ABDBE ABFSG ABRTQ ACSTC ADHKG AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION CGR CUY CVF ECM EIF NPM 7X8
ID	FETCH-LOGICAL-c544t-a06ae439409d80887e851f6a469bdf2b5da7fde5901e83712dd973b067d6b0c73
IEDL.DBID	RSV
ISICitedReferencesCount	667
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000418611900001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1340-6868 1880-4233
IngestDate	Thu Oct 02 06:10:39 EDT 2025 Sat Nov 29 13:05:35 EST 2025 Sat Nov 29 10:20:13 EST 2025 Thu Apr 03 07:03:22 EDT 2025 Sat Nov 29 06:41:45 EST 2025 Tue Nov 18 21:53:07 EST 2025 Fri Feb 21 02:35:27 EST 2025
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	1
Keywords	Circular RNA Biomarker MicroRNA Cancer
Language	English
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c544t-a06ae439409d80887e851f6a469bdf2b5da7fde5901e83712dd973b067d6b0c73
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
OpenAccessLink	https://doi.org/10.1007/s12282-017-0793-9
PMID	28721656
PQID	1920394715
PQPubID	23479
PageCount	7
ParticipantIDs	proquest_miscellaneous_1920394715 gale_infotracmisc_A712279994 gale_infotracacademiconefile_A712279994 pubmed_primary_28721656 crossref_primary_10_1007_s12282_017_0793_9 crossref_citationtrail_10_1007_s12282_017_0793_9 springer_journals_10_1007_s12282_017_0793_9
PublicationCentury	2000
PublicationDate	2018-01-01
PublicationDateYYYYMMDD	2018-01-01
PublicationDate_xml	– month: 01 year: 2018 text: 2018-01-01 day: 01
PublicationDecade	2010
PublicationPlace	Tokyo
PublicationPlace_xml	– name: Tokyo – name: Japan
PublicationTitle	Breast cancer (Tokyo, Japan)
PublicationTitleAbbrev	Breast Cancer
PublicationTitleAlternate	Breast Cancer
PublicationYear	2018
Publisher	Springer Japan Springer
Publisher_xml	– name: Springer Japan – name: Springer
References	Du, Fang, Yang, Wu, Awan, Yang (CR68) 2017; 24 Ekoff, Kaufmann, Engstrom, Motoyama, Villunger, Jönsson (CR67) 2007; 110 Jeck, Sharpless (CR37) 2014; 32 Peng, Yuan, Li (CR30) 2015; 33 Bartel (CR17) 2009; 136 Kulcheski, Christoff, Margis (CR15) 2016; 238 Lagos-Quintana, Rauhut, Lendeckel, Tuschl (CR52) 2001; 294 Yu, Gong, Sun, Zhou, Lu, Zhu (CR57) 2016; 11 Salzman, Chen, Olsen, Wang, Brown (CR3) 2013; 9 Burd, Jeck, Liu, Sanoff, Wang, Sharpless (CR19) 2010; 6 Hentze, Preiss (CR11) 2013; 32 Hansen, Jensen, Clausen, Bramsen, Finsen, Damgaard (CR7) 2013; 495 Qin, Liu, Huo, Tao, Sun, Ge (CR26) 2016; 16 Dou, Cha, Franklin, Higginbotham, Jeppesen, Weaver (CR47) 2016; 6 Sasaki, Yamada, Tanaka, Peng, Liu, Shi (CR48) 2006; 244 Zheng, Bao, Guo, Li, Chen, Chen (CR27) 2016; 7 Llovet, Zucman-Rossi, Pikarsky, Gores (CR50) 2016; 2 Kong, Piao, Yamashita, Oshima, Oguma, Fushida (CR55) 2012; 31 Guo, Agarwal, Guo, Bartel (CR8) 2014; 15 Jemal, Bray, Center, Ferlay, Ward, Forman (CR42) 2011; 61 Li, Zhang, Li, Deng, Zheng, An (CR20) 2015; 6 Yang, Du, Li, Yee, Yang (CR63) 2016; 35 Zhang, Dong, Zhu, Tsoi, Zhao, Wu (CR64) 2014; 13 Salzman, Gawad, Wang, Lacayo, Brown (CR2) 2012; 7 Lukiw, Circular (CR40) 2013; 4 Suzuki, Zuo, Wang, Zhang, Malhotra, Mayeda (CR13) 2006; 34 Hansen, Wiklund, Bramsen, Villadsen, Statham, Clark (CR38) 2011; 30 Chang, Yu, Hsieh, Yao, Chao, Chen (CR35) 2016; 7 Jeck, Sorrentino, Wang, Slevin, Burd, Liu (CR12) 2013; 19 Du, Yang, Liu, Yang, Dhaliwal, Yang (CR65) 2016; 44 Cho, Kuo, Liu, Yang, Hsieh, Wang (CR61) 2014; 5 Zhang, Zhang, Chen, Xiang, Yin, Xing (CR4) 2013; 51 Zhang, Du (CR46) 2016; 22 Ghosal, Das, Sen, Basak, Chakrabarti (CR21) 2013; 4 Bachmayr-Heyda, Reiner, Auer, Sukhbaatar, Aust, Bachleitner-Hofmann (CR23) 2015; 5 Li, Zheng, Bao, Li, Guo, Zhao (CR28) 2015; 25 Bahn, Zhang, Li, Chan, Lin, Kim (CR25) 2015; 61 Anderson, Viars, Czekay, Cavenee, Arden (CR59) 1998; 47 Du, Yang, Fang, Xuan, Li, Khorshidi (CR62) 2014; 5 Li, Zheng, Sun, Xiong (CR56) 2014; 32 Vicens, Westhof (CR33) 2014; 159 CR58 Zhang, Jiang, Sun, Li, Tang (CR16) 2015; 36 Zhou, Arcila, Li, Lee, Henzler, Liu (CR32) 2012; 40 Enzinger, Mayer (CR43) 2003; 349 Li, Chen, Chen, Mo, Li, Shao (CR6) 2015; 444 Shang, Li, Liu, Li, Liu, Zhao (CR51) 2016; 95 Chen, Yang (CR10) 2015; 12 Memczak, Jens, Elefsinioti, Torti, Krueger, Rybak (CR5) 2013; 495 Capel, Swain, Nicolis, Hacker, Walter, Koopman (CR41) 1993; 73 Westholm, Miura, Olson, Shenker, Joseph, Sanfilippo (CR24) 2014; 9 Chen, Li, Tan, Liu (CR39) 2016; 53 Liu, Huang, Zhang, Ju, Wu, Wang (CR18) 2015; 75 Myatt, Lam (CR60) 2007; 7 Nair, Niu, Tang (CR9) 2016; 7 Xia, Qiu, Chen, Wang, Leng, Wang (CR45) 2016; 6 Bruix, Gores, Mazzaferro (CR49) 2014; 63 Zhao, Shen (CR34) 2015; 9 Zhang, Wang, Zhang, Lu, Chen, Yang (CR29) 2014; 159 Jiang, Liu, Chen, Jin, Heidbreder, Kolokythas (CR53) 2010; 432 Hansen, Kjems, Damgaard (CR22) 2013; 73 Su, Lin, Deng, Shen, Fang, Fei (CR44) 2016; 14 Taulli, Loretelli, Pandolfi (CR36) 2013; 20 Ashwal-Fluss, Meyer, Pamudurti, Ivanov, Bartok, Hanan (CR31) 2014; 56 Qu, Yang, Li, Wang, Gao, Shang (CR14) 2015; 365 Tokino, Nakamura (CR66) 2000; 33 Cocquerelle, Mascrez, Hétuin, Bailleul (CR1) 1993; 7 Kefas, Godlewski, Comeau, Li, Abounader, Hawkinson (CR54) 2008; 68 J Salzman (793_CR3) 2013; 9 P Li (793_CR6) 2015; 444 J Bruix (793_CR49) 2014; 63 PC Enzinger (793_CR43) 2003; 349 SS Myatt (793_CR60) 2007; 7 S Memczak (793_CR5) 2013; 495 HD Zhang (793_CR16) 2015; 36 R Taulli (793_CR36) 2013; 20 M Lagos-Quintana (793_CR52) 2001; 294 W Xia (793_CR45) 2016; 6 WW Du (793_CR62) 2014; 5 L Yu (793_CR57) 2016; 11 WW Du (793_CR68) 2017; 24 M Liu (793_CR18) 2015; 75 L Jiang (793_CR53) 2010; 432 WR Jeck (793_CR12) 2013; 19 L Zhang (793_CR64) 2014; 13 XO Zhang (793_CR29) 2014; 159 B Kefas (793_CR54) 2008; 68 Y Chen (793_CR39) 2016; 53 M Qin (793_CR26) 2016; 16 M Zhang (793_CR46) 2016; 22 FR Kulcheski (793_CR15) 2016; 238 ZJ Zhao (793_CR34) 2015; 9 Y Li (793_CR28) 2015; 25 A Bachmayr-Heyda (793_CR23) 2015; 5 JM Llovet (793_CR50) 2016; 2 S Ghosal (793_CR21) 2013; 4 D Kong (793_CR55) 2012; 31 JU Guo (793_CR8) 2014; 15 Y Dou (793_CR47) 2016; 6 Y Sasaki (793_CR48) 2006; 244 C Cocquerelle (793_CR1) 1993; 7 W Yang (793_CR63) 2016; 35 WR Jeck (793_CR37) 2014; 32 TB Hansen (793_CR22) 2013; 73 X Shang (793_CR51) 2016; 95 L Peng (793_CR30) 2015; 33 WW Du (793_CR65) 2016; 44 H Zhou (793_CR32) 2012; 40 793_CR58 MW Hentze (793_CR11) 2013; 32 TB Hansen (793_CR7) 2013; 495 MJ Anderson (793_CR59) 1998; 47 F Li (793_CR20) 2015; 6 CE Burd (793_CR19) 2010; 6 B Capel (793_CR41) 1993; 73 Q Zheng (793_CR27) 2016; 7 AA Nair (793_CR9) 2016; 7 J Salzman (793_CR2) 2012; 7 LL Chen (793_CR10) 2015; 12 JO Westholm (793_CR24) 2014; 9 A Jemal (793_CR42) 2011; 61 M Ekoff (793_CR67) 2007; 110 S Qu (793_CR14) 2015; 365 Y Zhang (793_CR4) 2013; 51 JH Bahn (793_CR25) 2015; 61 Q Vicens (793_CR33) 2014; 159 DP Bartel (793_CR17) 2009; 136 TB Hansen (793_CR38) 2011; 30 CW Chang (793_CR35) 2016; 7 R Ashwal-Fluss (793_CR31) 2014; 56 WJ Lukiw (793_CR40) 2013; 4 EC Cho (793_CR61) 2014; 5 H Suzuki (793_CR13) 2006; 34 H Su (793_CR44) 2016; 14 T Tokino (793_CR66) 2000; 33 J Li (793_CR56) 2014; 32
References_xml	– volume: 15 start-page: 409 issue: 7 year: 2014 ident: CR8 article-title: Expanded identification and characterization of mammalian circular RNAs publication-title: Genome Biol doi: 10.1186/s13059-014-0409-z – volume: 47 start-page: 187 issue: 2 year: 1998 end-page: 199 ident: CR59 article-title: Cloning and characterization of three human fork head genes that comprise an FKHR-like gene subfamily publication-title: Genomics doi: 10.1006/geno.1997.5122 – volume: 5 start-page: e1355 year: 2014 ident: CR62 article-title: miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7 publication-title: Cell Death Dis. doi: 10.1038/cddis.2014.305 – volume: 32 start-page: 2511 issue: 6 year: 2014 end-page: 2516 ident: CR56 article-title: Restoration of miR-7 expression suppresses the growth of Lewis lung cancer cells by modulating epidermal growth factor receptor signaling publication-title: Oncol Rep doi: 10.3892/or.2014.3519 – volume: 7 start-page: 847 issue: 11 year: 2007 end-page: 859 ident: CR60 article-title: The emerging roles of forkhead box (Fox) proteins in cancer publication-title: Nat Rev Cancer doi: 10.1038/nrc2223 – volume: 9 start-page: 1966 issue: 5 year: 2014 end-page: 1980 ident: CR24 article-title: Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation publication-title: Cell Rep. doi: 10.1016/j.celrep.2014.10.062 – volume: 11 start-page: e0158347 issue: 7 year: 2016 ident: CR57 article-title: The circular RNA Cdr1as act as an oncogene in hepatocellular carcinoma through targeting miR-7 expression publication-title: PLoS One doi: 10.1371/journal.pone.0158347 – volume: 5 start-page: 8057 year: 2015 ident: CR23 article-title: Correlation of circular RNA abundance with proliferation-exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues publication-title: Sci Rep doi: 10.1038/srep08057 – volume: 4 start-page: 307 year: 2013 ident: CR40 article-title: circRNA) in Alzheimer’s disease (AD publication-title: Front Genet – volume: 73 start-page: 1019 issue: 5 year: 1993 end-page: 1030 ident: CR41 article-title: Circular transcripts of the testis-determining gene Sry in adult mouse testis publication-title: Cell doi: 10.1016/0092-8674(93)90279-Y – volume: 25 start-page: 981 issue: 8 year: 2015 end-page: 984 ident: CR28 article-title: Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis publication-title: Cell Res doi: 10.1038/cr.2015.82 – ident: CR58 – volume: 6 start-page: 37982 year: 2016 ident: CR47 article-title: Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes publication-title: Sci Rep. doi: 10.1038/srep37982 – volume: 24 start-page: 357 issue: 2 year: 2017 end-page: 370 ident: CR68 article-title: Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity publication-title: Cell Death Differ doi: 10.1038/cdd.2016.133 – volume: 61 start-page: 69 issue: 2 year: 2011 end-page: 90 ident: CR42 article-title: Global cancer statistics publication-title: CA Cancer J Clin doi: 10.3322/caac.20107 – volume: 5 start-page: 4834 issue: 13 year: 2014 end-page: 4844 ident: CR61 article-title: Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients publication-title: Oncotarget. doi: 10.18632/oncotarget.2044 – volume: 444 start-page: 132 year: 2015 end-page: 136 ident: CR6 article-title: Using circular RNA as a novel type of biomarker in the screening of gastric cancer publication-title: Clin Chim Acta doi: 10.1016/j.cca.2015.02.018 – volume: 6 start-page: e1001233 issue: 12 year: 2010 ident: CR19 article-title: Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk publication-title: PLoS Genet doi: 10.1371/journal.pgen.1001233 – volume: 7 start-page: 16462 issue: 13 year: 2016 end-page: 16478 ident: CR35 article-title: MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer publication-title: Oncotarget. doi: 10.18632/oncotarget.7656 – volume: 53 start-page: 359 issue: 6 year: 2016 end-page: 365 ident: CR39 article-title: Circular RNAs: a new frontier in the study of human diseases publication-title: J Med Genet doi: 10.1136/jmedgenet-2016-103758 – volume: 44 start-page: 2846 issue: 6 year: 2016 end-page: 2858 ident: CR65 article-title: Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkw027 – volume: 9 start-page: 1 year: 2015 end-page: 8 ident: CR34 article-title: Circular RNA participates in the carcinogenesis and the malignant behavior of cancer publication-title: RNA Biol – volume: 32 start-page: 453 issue: 5 year: 2014 end-page: 461 ident: CR37 article-title: Detecting and characterizing circular RNAs publication-title: Nat Biotechnol doi: 10.1038/nbt.2890 – volume: 365 start-page: 141 issue: 2 year: 2015 end-page: 148 ident: CR14 article-title: Circular RNA: a new star of noncoding RNAs publication-title: Cancer Lett doi: 10.1016/j.canlet.2015.06.003 – volume: 95 start-page: e3811 issue: 22 year: 2016 ident: CR51 article-title: Comprehensive circular RNA profiling reveals that hsa_circ_0005075, a new circular RNA biomarker, is involved in hepatocellular carcinoma development publication-title: Medicine (Baltimore). doi: 10.1097/MD.0000000000003811 – volume: 9 start-page: e1003777 issue: 9 year: 2013 ident: CR3 article-title: Cell-type specific features of circular RNA expression publication-title: PLoS Genet doi: 10.1371/journal.pgen.1003777 – volume: 495 start-page: 384 issue: 7441 year: 2013 end-page: 388 ident: CR7 article-title: Natural RNA circles function as efficient microRNA sponges publication-title: Nature doi: 10.1038/nature11993 – volume: 51 start-page: 792 issue: 6 year: 2013 end-page: 806 ident: CR4 article-title: Circular intronic long noncoding RNAs publication-title: Mol Cell doi: 10.1016/j.molcel.2013.08.017 – volume: 33 start-page: 1 issue: 1 year: 2000 end-page: 6 ident: CR66 article-title: The role of p53-target genes in human cancer publication-title: Crit Rev Oncol Hematol doi: 10.1016/S1040-8428(99)00051-7 – volume: 22 start-page: 6610 issue: 29 year: 2016 end-page: 6618 ident: CR46 article-title: Noncoding RNAs in gastric cancer: research progress and prospects publication-title: World J Gastroenterol doi: 10.3748/wjg.v22.i29.6610 – volume: 61 start-page: 221 issue: 1 year: 2015 end-page: 230 ident: CR25 article-title: The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva publication-title: Clin Chem doi: 10.1373/clinchem.2014.230433 – volume: 36 start-page: 1355 issue: 3 year: 2015 end-page: 1365 ident: CR16 article-title: MiR-139-5p: promising biomarker for cancer publication-title: Tumour Biol doi: 10.1007/s13277-015-3199-3 – volume: 12 start-page: 381 issue: 4 year: 2015 end-page: 388 ident: CR10 article-title: Regulation of circRNA biogenesis publication-title: RNA Biol doi: 10.1080/15476286.2015.1020271 – volume: 432 start-page: 199 issue: 1 year: 2010 end-page: 205 ident: CR53 article-title: microRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells publication-title: Biochem J. doi: 10.1042/BJ20100859 – volume: 56 start-page: 55 issue: 1 year: 2014 end-page: 66 ident: CR31 article-title: circRNA biogenesis competes with pre-mRNA splicing publication-title: Mol Cell doi: 10.1016/j.molcel.2014.08.019 – volume: 244 start-page: 771 issue: 5 year: 2006 end-page: 780 ident: CR48 article-title: Risk of recurrence in a long-term follow-up after surgery in 417 patients with hepatitis B or hepatitis C related hepatocellular carcinoma publication-title: Ann Surg doi: 10.1097/01.sla.0000225126.56483.b3 – volume: 40 start-page: 5864 issue: 13 year: 2012 end-page: 5875 ident: CR32 article-title: Deep annotation of mouse iso-miR and iso-moR variation publication-title: Nucleic Acids Res doi: 10.1093/nar/gks247 – volume: 7 start-page: 80967 issue: 49 year: 2016 end-page: 80979 ident: CR9 article-title: Circular RNAs and their associations with breast cancer subtypes publication-title: Oncotarget – volume: 7 start-page: 11215 year: 2016 ident: CR27 article-title: Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs publication-title: Nat Commun. doi: 10.1038/ncomms11215 – volume: 20 start-page: 541 issue: 5 year: 2013 end-page: 543 ident: CR36 article-title: From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb.2580 – volume: 63 start-page: 844 issue: 5 year: 2014 end-page: 855 ident: CR49 article-title: Hepatocellular carcinoma: clinical frontiers and perspectives publication-title: Gut doi: 10.1136/gutjnl-2013-306627 – volume: 32 start-page: 923 issue: 7 year: 2013 end-page: 925 ident: CR11 article-title: Circular RNAs: splicing’s enigma variations publication-title: EMBO J doi: 10.1038/emboj.2013.53 – volume: 294 start-page: 853 issue: 5543 year: 2001 end-page: 858 ident: CR52 article-title: Identification of novel genes coding for small expressed RNAs publication-title: Science doi: 10.1126/science.1064921 – volume: 6 start-page: 6001 issue: 8 year: 2015 end-page: 6013 ident: CR20 article-title: Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway publication-title: Oncotarget. doi: 10.18632/oncotarget.3469 – volume: 73 start-page: 5609 issue: 18 year: 2013 end-page: 5612 ident: CR22 article-title: Circular RNA and miR-7 in cancer publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-13-1568 – volume: 7 start-page: e30733 issue: 2 year: 2012 ident: CR2 article-title: Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types publication-title: PLoS One doi: 10.1371/journal.pone.0030733 – volume: 68 start-page: 3566 issue: 10 year: 2008 end-page: 3572 ident: CR54 article-title: microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-07-6639 – volume: 495 start-page: 333 issue: 7441 year: 2013 end-page: 338 ident: CR5 article-title: Circular RNAs are a large class of animal RNAs with regulatory potency publication-title: Nature doi: 10.1038/nature11928 – volume: 159 start-page: 13 issue: 1 year: 2014 end-page: 14 ident: CR33 article-title: Biogenesis of circular RNAs publication-title: Cell doi: 10.1016/j.cell.2014.09.005 – volume: 136 start-page: 215 issue: 2 year: 2009 end-page: 233 ident: CR17 article-title: MicroRNAs: target recognition and regulatory functions publication-title: Cell doi: 10.1016/j.cell.2009.01.002 – volume: 34 start-page: e63 issue: 8 year: 2006 ident: CR13 article-title: Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing publication-title: Nucleic Acids Res doi: 10.1093/nar/gkl151 – volume: 31 start-page: 3949 issue: 35 year: 2012 end-page: 3960 ident: CR55 article-title: Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells publication-title: Oncogene doi: 10.1038/onc.2011.558 – volume: 110 start-page: 3209 year: 2007 end-page: 3217 ident: CR67 article-title: The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells publication-title: Blood doi: 10.1182/blood-2007-02-073957 – volume: 33 start-page: 2669 issue: 6 year: 2015 end-page: 2674 ident: CR30 article-title: The emerging landscape of circular RNA ciRS-7 in cancer publication-title: Oncol Rep doi: 10.3892/or.2015.3904 – volume: 35 start-page: 3919 issue: 30 year: 2016 end-page: 3931 ident: CR63 article-title: Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis publication-title: Oncogene doi: 10.1038/onc.2015.460 – volume: 159 start-page: 134 year: 2014 end-page: 147 ident: CR29 article-title: Complementary sequence-mediated exon circularization publication-title: Cell doi: 10.1016/j.cell.2014.09.001 – volume: 19 start-page: 141 issue: 2 year: 2013 end-page: 157 ident: CR12 article-title: Circular RNAs are abundant, conserved, and associated with ALU repeats publication-title: RNA doi: 10.1261/rna.035667.112 – volume: 30 start-page: 4414 issue: 21 year: 2011 end-page: 4422 ident: CR38 article-title: miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA publication-title: EMBO J doi: 10.1038/emboj.2011.359 – volume: 16 start-page: 161 issue: 1 year: 2016 end-page: 169 ident: CR26 article-title: Hsa_circ_0001649: a circular RNA and potential novel biomarker for hepatocellular carcinoma publication-title: Cancer Biomark. doi: 10.3233/CBM-150552 – volume: 238 start-page: 42 year: 2016 end-page: 51 ident: CR15 article-title: Circular RNAs are miRNA sponges and can be used as a new class of biomarker publication-title: J Biotechnol doi: 10.1016/j.jbiotec.2016.09.011 – volume: 75 start-page: 4593 issue: 21 year: 2015 end-page: 4604 ident: CR18 article-title: Heterochromatin protein HP1γ promotes colorectal cancer progression and is regulated by miR-30a publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-14-3735 – volume: 349 start-page: 2241 issue: 23 year: 2003 end-page: 2252 ident: CR43 article-title: Esophageal cancer publication-title: N Engl J Med doi: 10.1056/NEJMra035010 – volume: 13 start-page: 124 year: 2014 ident: CR64 article-title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer publication-title: Mol Cancer. doi: 10.1186/1476-4598-13-124 – volume: 14 start-page: 225 issue: 1 year: 2016 ident: CR44 article-title: Profiling and bioinformatics analyses reveal differential circular RNA expression in radioresistant esophageal cancer cells publication-title: J Transl Med. doi: 10.1186/s12967-016-0977-7 – volume: 7 start-page: 155 issue: 1 year: 1993 end-page: 160 ident: CR1 article-title: Mis-splicing yields circular RNA molecules publication-title: FASEB J. – volume: 6 start-page: 3 year: 2016 ident: CR45 article-title: Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation publication-title: Sci Rep. doi: 10.1038/s41598-016-0007-2 – volume: 2 start-page: 16018 year: 2016 ident: CR50 article-title: Hepatocellular carcinoma publication-title: Nat Rev Dis Primers. doi: 10.1038/nrdp.2016.18 – volume: 4 start-page: 283 year: 2013 ident: CR21 article-title: Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits publication-title: Front Genet. doi: 10.3389/fgene.2013.00283 – volume: 4 start-page: 283 year: 2013 ident: 793_CR21 publication-title: Front Genet. doi: 10.3389/fgene.2013.00283 – volume: 19 start-page: 141 issue: 2 year: 2013 ident: 793_CR12 publication-title: RNA doi: 10.1261/rna.035667.112 – volume: 159 start-page: 134 year: 2014 ident: 793_CR29 publication-title: Cell doi: 10.1016/j.cell.2014.09.001 – volume: 95 start-page: e3811 issue: 22 year: 2016 ident: 793_CR51 publication-title: Medicine (Baltimore). doi: 10.1097/MD.0000000000003811 – volume: 136 start-page: 215 issue: 2 year: 2009 ident: 793_CR17 publication-title: Cell doi: 10.1016/j.cell.2009.01.002 – volume: 75 start-page: 4593 issue: 21 year: 2015 ident: 793_CR18 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-14-3735 – volume: 6 start-page: 6001 issue: 8 year: 2015 ident: 793_CR20 publication-title: Oncotarget. doi: 10.18632/oncotarget.3469 – volume: 9 start-page: e1003777 issue: 9 year: 2013 ident: 793_CR3 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1003777 – volume: 495 start-page: 384 issue: 7441 year: 2013 ident: 793_CR7 publication-title: Nature doi: 10.1038/nature11993 – volume: 61 start-page: 69 issue: 2 year: 2011 ident: 793_CR42 publication-title: CA Cancer J Clin doi: 10.3322/caac.20107 – volume: 6 start-page: e1001233 issue: 12 year: 2010 ident: 793_CR19 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1001233 – volume: 61 start-page: 221 issue: 1 year: 2015 ident: 793_CR25 publication-title: Clin Chem doi: 10.1373/clinchem.2014.230433 – volume: 22 start-page: 6610 issue: 29 year: 2016 ident: 793_CR46 publication-title: World J Gastroenterol doi: 10.3748/wjg.v22.i29.6610 – volume: 24 start-page: 357 issue: 2 year: 2017 ident: 793_CR68 publication-title: Cell Death Differ doi: 10.1038/cdd.2016.133 – volume: 33 start-page: 1 issue: 1 year: 2000 ident: 793_CR66 publication-title: Crit Rev Oncol Hematol doi: 10.1016/S1040-8428(99)00051-7 – volume: 12 start-page: 381 issue: 4 year: 2015 ident: 793_CR10 publication-title: RNA Biol doi: 10.1080/15476286.2015.1020271 – volume: 4 start-page: 307 year: 2013 ident: 793_CR40 publication-title: Front Genet – volume: 32 start-page: 923 issue: 7 year: 2013 ident: 793_CR11 publication-title: EMBO J doi: 10.1038/emboj.2013.53 – volume: 444 start-page: 132 year: 2015 ident: 793_CR6 publication-title: Clin Chim Acta doi: 10.1016/j.cca.2015.02.018 – volume: 294 start-page: 853 issue: 5543 year: 2001 ident: 793_CR52 publication-title: Science doi: 10.1126/science.1064921 – volume: 73 start-page: 1019 issue: 5 year: 1993 ident: 793_CR41 publication-title: Cell doi: 10.1016/0092-8674(93)90279-Y – volume: 7 start-page: 11215 year: 2016 ident: 793_CR27 publication-title: Nat Commun. doi: 10.1038/ncomms11215 – volume: 6 start-page: 3 year: 2016 ident: 793_CR45 publication-title: Sci Rep. doi: 10.1038/s41598-016-0007-2 – volume: 110 start-page: 3209 year: 2007 ident: 793_CR67 publication-title: Blood doi: 10.1182/blood-2007-02-073957 – volume: 53 start-page: 359 issue: 6 year: 2016 ident: 793_CR39 publication-title: J Med Genet doi: 10.1136/jmedgenet-2016-103758 – volume: 14 start-page: 225 issue: 1 year: 2016 ident: 793_CR44 publication-title: J Transl Med. doi: 10.1186/s12967-016-0977-7 – volume: 20 start-page: 541 issue: 5 year: 2013 ident: 793_CR36 publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb.2580 – volume: 11 start-page: e0158347 issue: 7 year: 2016 ident: 793_CR57 publication-title: PLoS One doi: 10.1371/journal.pone.0158347 – volume: 9 start-page: 1966 issue: 5 year: 2014 ident: 793_CR24 publication-title: Cell Rep. doi: 10.1016/j.celrep.2014.10.062 – volume: 73 start-page: 5609 issue: 18 year: 2013 ident: 793_CR22 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-13-1568 – volume: 34 start-page: e63 issue: 8 year: 2006 ident: 793_CR13 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkl151 – volume: 68 start-page: 3566 issue: 10 year: 2008 ident: 793_CR54 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-07-6639 – volume: 7 start-page: e30733 issue: 2 year: 2012 ident: 793_CR2 publication-title: PLoS One doi: 10.1371/journal.pone.0030733 – volume: 5 start-page: 4834 issue: 13 year: 2014 ident: 793_CR61 publication-title: Oncotarget. doi: 10.18632/oncotarget.2044 – volume: 63 start-page: 844 issue: 5 year: 2014 ident: 793_CR49 publication-title: Gut doi: 10.1136/gutjnl-2013-306627 – volume: 47 start-page: 187 issue: 2 year: 1998 ident: 793_CR59 publication-title: Genomics doi: 10.1006/geno.1997.5122 – volume: 432 start-page: 199 issue: 1 year: 2010 ident: 793_CR53 publication-title: Biochem J. doi: 10.1042/BJ20100859 – volume: 9 start-page: 1 year: 2015 ident: 793_CR34 publication-title: RNA Biol – volume: 5 start-page: e1355 year: 2014 ident: 793_CR62 publication-title: Cell Death Dis. doi: 10.1038/cddis.2014.305 – volume: 7 start-page: 847 issue: 11 year: 2007 ident: 793_CR60 publication-title: Nat Rev Cancer doi: 10.1038/nrc2223 – volume: 244 start-page: 771 issue: 5 year: 2006 ident: 793_CR48 publication-title: Ann Surg doi: 10.1097/01.sla.0000225126.56483.b3 – volume: 7 start-page: 155 issue: 1 year: 1993 ident: 793_CR1 publication-title: FASEB J. doi: 10.1096/fasebj.7.1.7678559 – volume: 159 start-page: 13 issue: 1 year: 2014 ident: 793_CR33 publication-title: Cell doi: 10.1016/j.cell.2014.09.005 – volume: 495 start-page: 333 issue: 7441 year: 2013 ident: 793_CR5 publication-title: Nature doi: 10.1038/nature11928 – ident: 793_CR58 doi: 10.1007/s00432-016-2256-7 – volume: 51 start-page: 792 issue: 6 year: 2013 ident: 793_CR4 publication-title: Mol Cell doi: 10.1016/j.molcel.2013.08.017 – volume: 40 start-page: 5864 issue: 13 year: 2012 ident: 793_CR32 publication-title: Nucleic Acids Res doi: 10.1093/nar/gks247 – volume: 13 start-page: 124 year: 2014 ident: 793_CR64 publication-title: Mol Cancer. doi: 10.1186/1476-4598-13-124 – volume: 7 start-page: 80967 issue: 49 year: 2016 ident: 793_CR9 publication-title: Oncotarget doi: 10.18632/oncotarget.13134 – volume: 44 start-page: 2846 issue: 6 year: 2016 ident: 793_CR65 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkw027 – volume: 365 start-page: 141 issue: 2 year: 2015 ident: 793_CR14 publication-title: Cancer Lett doi: 10.1016/j.canlet.2015.06.003 – volume: 2 start-page: 16018 year: 2016 ident: 793_CR50 publication-title: Nat Rev Dis Primers. doi: 10.1038/nrdp.2016.18 – volume: 56 start-page: 55 issue: 1 year: 2014 ident: 793_CR31 publication-title: Mol Cell doi: 10.1016/j.molcel.2014.08.019 – volume: 35 start-page: 3919 issue: 30 year: 2016 ident: 793_CR63 publication-title: Oncogene doi: 10.1038/onc.2015.460 – volume: 6 start-page: 37982 year: 2016 ident: 793_CR47 publication-title: Sci Rep. doi: 10.1038/srep37982 – volume: 7 start-page: 16462 issue: 13 year: 2016 ident: 793_CR35 publication-title: Oncotarget. doi: 10.18632/oncotarget.7656 – volume: 15 start-page: 409 issue: 7 year: 2014 ident: 793_CR8 publication-title: Genome Biol doi: 10.1186/s13059-014-0409-z – volume: 30 start-page: 4414 issue: 21 year: 2011 ident: 793_CR38 publication-title: EMBO J doi: 10.1038/emboj.2011.359 – volume: 32 start-page: 2511 issue: 6 year: 2014 ident: 793_CR56 publication-title: Oncol Rep doi: 10.3892/or.2014.3519 – volume: 36 start-page: 1355 issue: 3 year: 2015 ident: 793_CR16 publication-title: Tumour Biol doi: 10.1007/s13277-015-3199-3 – volume: 32 start-page: 453 issue: 5 year: 2014 ident: 793_CR37 publication-title: Nat Biotechnol doi: 10.1038/nbt.2890 – volume: 349 start-page: 2241 issue: 23 year: 2003 ident: 793_CR43 publication-title: N Engl J Med doi: 10.1056/NEJMra035010 – volume: 33 start-page: 2669 issue: 6 year: 2015 ident: 793_CR30 publication-title: Oncol Rep doi: 10.3892/or.2015.3904 – volume: 31 start-page: 3949 issue: 35 year: 2012 ident: 793_CR55 publication-title: Oncogene doi: 10.1038/onc.2011.558 – volume: 5 start-page: 8057 year: 2015 ident: 793_CR23 publication-title: Sci Rep doi: 10.1038/srep08057 – volume: 16 start-page: 161 issue: 1 year: 2016 ident: 793_CR26 publication-title: Cancer Biomark. doi: 10.3233/CBM-150552 – volume: 238 start-page: 42 year: 2016 ident: 793_CR15 publication-title: J Biotechnol doi: 10.1016/j.jbiotec.2016.09.011 – volume: 25 start-page: 981 issue: 8 year: 2015 ident: 793_CR28 publication-title: Cell Res doi: 10.1038/cr.2015.82
SSID	ssj0043706
Score	2.6366003
SecondaryResourceType	review_article
Snippet	Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5′–3′ polarity and contain... Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a covalently closed continuous loop which have no 5'-3' polarity and contain...
SourceID	proquest gale pubmed crossref springer
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	1
SubjectTerms	Animals Biomarkers - analysis Blood circulation disorders Breast Neoplasms - diagnosis Breast Neoplasms - genetics Cancer Cancer Research Cells Colorectal cancer Female Genes Genetic aspects Genetic transcription Health aspects Humans Medicine Medicine & Public Health MicroRNA Oncology Osteoarthritis Review Article RNA - genetics RNA, Long Noncoding - genetics Surgery Surgical Oncology
Title	CircRNA: a novel type of biomarker for cancer
URI	https://link.springer.com/article/10.1007/s12282-017-0793-9 https://www.ncbi.nlm.nih.gov/pubmed/28721656 https://www.proquest.com/docview/1920394715
Volume	25
WOSCitedRecordID	wos000418611900001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAVX databaseName: SpringerLink Standard customDbUrl: eissn: 1880-4233 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0043706 issn: 1340-6868 databaseCode: RSV dateStart: 19970101 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1da9sw8FiyUvrSrd_usqJBodBicGQ5kvoWwspeFkq3lbwJSZahUJzipP39vXPspCldYXu2LI77Pt0XwClacZuS9ku05bGwAvUgms3YceWscFoG7etlE3I8VpOJvm76uGdttXubkqw19arZjWN4ENf3IlPFugMf0dopksabX7et-hWprBdq9lOqa1cD1aYy37pizRi9VskvbNKrJGlte64-_RfUn2G7cTXZcMEbO_AhlLuw-bNJpu9BPLqr_M14eMksK6dP4Z7ReyybFox68qlsp2Lo0jJPjFHtw5-r779HP-Jme0LsMyHmsU0GNlDfa6JzRbokIBGKgcV42OUFd1luZZEH6j0NGKX2eZ5rmTq0XvnAJV6mB9Atp2U4AlbopBBFnmnOtSiSYLlPnU3TrK-0c8pFkLRoNL4ZLU4bLu7NaigyocEgGgyhwegIzpe_PCzmarx3-IxoY0jm8F5vm9YBhI6mV5khQs8luroigt7aSZQVv_b5W0tdQ5-owKwM08eZQUc3QVzJfhbB4YLsS7gwqOQ0pCiCi5bGppH02d-BPv6n019gC10xtXjc6UF3Xj2Gr7Dhn-Z3s-oEOnKiTmo-fwZoMvAz
linkProvider	Springer Nature
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR3ZSsQwcNBV1Bfvo54RBEEpdNN02_i2iKKoi3jhW0jSFATpSnf1-53ptq4rKuhzDoaZyRyZC2APtbgOSfoFUnNfaIFyENWmb3hitDAydtKWwybiTid5fJTXVR13r852r0OSpaQeFrtxdA_88l5kKl-Ow4RAhUV5fDe3D7X4FWFcDtRshpTXnrSSOpT53RUjyuirSP6kk74ESUvdczr3L6jnYbYyNVl7wBsLMObyRZi6qoLpS-AfPxX2ptM-Yprl3Tf3zOg_lnUzRjX5lLZTMDRpmSXGKJbh_vTk7vjMr6Yn-DYSou_roKUd1b0GMk1IljgkQtbS6A-bNOMmSnWcpY5qTx16qU2epjIODWqvtGUCG4cr0Mi7uVsDlskgE1kaSc6lyAKnuQ2NDsOomUhjEuNBUKNR2aq1OE24eFbDpsiEBoVoUIQGJT04-DjyMuir8dvmfaKNojeH91pdlQ4gdNS9SrUReh6jqSs82BzZiW_Fjizv1tRVtEQJZrnrvvYUGroB4ipuRh6sDsj-ARc6lZyaFHlwWNNYVS-99zPQ63_avQPTZ3dXl-ryvHOxATNoliWDj55NaPSLV7cFk_at_9QrtktufwcJxvIv
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpR1rS9xAcPCF9EsfPtq01m5BECrB3GZzyfrtUA-l7SFqi9-WfYIgOcmd_v7O5KGeVEH8nM1mMjM7j50XwBZqcZ2S9Euk5rHQAuUgqs3Y8MJoYWTupa2HTeSjUXFxIU_aOaeTLtu9C0k2NQ3Upamc7l67sHtf-MbRVYjrbyCDxXIeFgXNDCJ3_exvJ4pFmtfDNXsp5bgX_aILa_5vixnF9Fg8P9BPjwKmtR4avnv1H7yHt60JygYNz3yAOV-uwPLvNsi-CvH-ZWVPR4M9plk5vvVXjO5p2TgwqtWndJ6KoanLLDFMtQZ_hofn-0dxO1UhtpkQ01gnfe2pHjaRriAZ45E4oa_RTzYucJM5nQfnqSbVo_fa487JPDWo1VzfJDZP12GhHJf-E7AgkyCCyyTnUoTEa25To9M06xXSmMJEkHQoVbZtOU6TL67UfbNkQoNCNChCg5IR_Lh75brpt_Hc4m2ik6KziPta3ZYUIHTU1UoNEHqeowksItiYWYlnyM48_t5RWtEjSjwr_fhmotAAThBXeS-L4GPDAndwobPJqXlRBDsdvVUrASZPA_35Rau_wfLJwVD9Oh79_AJv0FormvufDViYVjf-KyzZ2-nlpNqsGf8fybH7Ew
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=CircRNA%3A+a+novel+type+of+biomarker+for+cancer&rft.jtitle=Breast+cancer+%28Tokyo%2C+Japan%29&rft.au=Zhang%2C+He-da&rft.au=Jiang%2C+Lin-hong&rft.au=Sun%2C+Da-wei&rft.au=Hou%2C+Jun-chen&rft.date=2018-01-01&rft.pub=Springer&rft.issn=1340-6868&rft.volume=25&rft.issue=1&rft.spage=1&rft_id=info:doi/10.1007%2Fs12282-017-0793-9&rft.externalDocID=A712279994
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1340-6868&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1340-6868&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1340-6868&client=summon