New Oxazolidinones for Tuberculosis: Are Novel Treatments on the Horizon?

Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity. As such, it is imperative to identify novel alterna...

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Bibliographic Details
Published in:	Pharmaceutics Vol. 16; no. 6; p. 818
Main Authors:	Chen, Ricky Hao, Burke, Andrew, Cho, Jin-Gun, Alffenaar, Jan-Willem, Davies Forsman, Lina
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 17.06.2024 MDPI
Subjects:	Clinical trials delpazolid Drug dosages Drug resistance eperezolid linezolid Metabolism Metabolites Pharmacokinetics Protein synthesis Proteins Review sutezolid tedizolid Toxicity Tuberculosis tuberculosis treatment United States > US sutezolid linezolid TBI-223 contezolid tuberculosis treatment eperezolid posizolid delpazolid tedizolid radezolid
ISSN:	1999-4923, 1999-4923
Online Access:	Get full text
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