Stereotactic body radiation therapy (SBRT) increases anti-PD-1 antitumor activity by enhancing the tumor immune microenvironment in mice with metastatic hepatocellular carcinoma

Background To explore the effect of radiotherapy on anti-pd-1 anti-tumor activity in metastatic hepatocellular carcinoma. Methods Patients with metastatic HCC treated with intensity-modulated radiation therapy (IMRT) in combination with immunotherapy ( n = 13) were retrospectively analyzed by compa...

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Bibliographic Details
Published in:	Discover. Oncology Vol. 16; no. 1; pp. 1081 - 19
Main Authors:	Xu, Ke, Gu, Tao, Su, Ke, Liu, Xin, He, Bingsheng, He, Jie, Chi, Hao, Zhou, Xuancheng, Liu, Hanlin, Xiao, Rui, Tang, Xue, Ye, Qinni, Zhou, Xue, Liu, Yingpeng, Xiong, Jie, Wang, Pan, Li, Han, He, Kun, Guo, Lu, Han, Yunwei
Format:	Journal Article
Language:	English
Published:	New York Springer US 13.06.2025 Springer Nature B.V Springer
Subjects:	Antibodies Biotechnology Cancer Research Cancer therapies Cell culture Disease Ethics Fatalities FDA approval Hepatitis Hospitals Hypoxia Immune system Immunotherapy Internal Medicine Liver cancer Liver cirrhosis Lymphocytes Medical research Medicine Medicine & Public Health Metastasis Metastatic hepatocellular carcinoma Molecular Medicine Oncology PD-1 antibody Penicillin Radiation therapy Radiotherapy Stereotactic body radiation therapy Surgical Oncology Toxic effects Transplants & implants Tumor immune microenvironment Tumors Viral infections United States > US China Tumor immune microenvironment Stereotactic body radiation therapy Toxic effects PD-1 antibody Immunotherapy Metastatic hepatocellular carcinoma
ISSN:	2730-6011, 2730-6011
Online Access:	Get full text
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