Association between Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and hypertension in a Ghanaian population

Genetic modifications in the renin-angiotensin aldosterone system (RAAS) have been suggested to play a key role in the pathophysiology of hypertension. The insertion/deletion polymorphism of angiotensin-converting enzyme (ACE) gene phenomenon and its relationship with essential hypertension has not...

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Vydáno v:	PloS one Ročník 19; číslo 12; s. e0311692
Hlavní autoři:	Bonney, Precious, Obirikorang, Christian, Quaye, Lawrence, Dapare, Peter Paul, Adams, Yussif, Bourawono, Grace, Akaluti, Mercy, Duodu, Jemimah
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 12.12.2024 Public Library of Science (PLoS)
Témata:	Adult Aged Aldosterone Alleles Angiotensin Angiotensin converting enzyme Biology and Life Sciences Blood & organ donations Blood pressure Body mass index Case-Control Studies Chi-square test Deletion Disease Electrolytes Enzymes Female Gene deletion Gene Frequency Gene polymorphism Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Genotype Genotype & phenotype Genotypes Ghana - epidemiology Health aspects Hospitals Humans Hypertension Hypertension - epidemiology Hypertension - genetics INDEL Mutation Insertion Male Medical phenomena Medical research Medicine and Health Sciences Medicine, Experimental Middle Aged Patients People and Places Peptidyl-dipeptidase A Peptidyl-Dipeptidase A - genetics Physiological aspects Polymerase chain reaction Polymorphism Polymorphism, Genetic Population genetics Population studies Renin Research and Analysis Methods Variance analysis Ghana
ISSN:	1932-6203, 1932-6203
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