Double hit & double expressor lymphomas: a multicenter analysis of survival outcomes with CD19-directed CAR T-cell therapy

Double-hit (DHL) and double expressor (DEL) DLBCL have poor prognosis with standard therapy but CART may overcome this poor prognostic impact. In this multicenter retrospective study, we sought to confirm this observation by evaluating survival outcomes among patients with relapsed/refractory DHL an...

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Bibliographic Details
Published in:	Blood cancer journal (New York) Vol. 15; no. 1; pp. 43 - 7
Main Authors:	Karmali, Reem, Shouse, Geoffrey, Torka, Pallawi, Moyo, Tamara K., Romancik, Jason, Barta, Stefan K., Bhansali, Rahul, Cohen, Jonathon B., Shah, Nirav N., Zurko, Joanna, Kenkre, Vaishalee P., Hess, Brian, Stephens, Deborah M., Fitzgerald, Lindsey, Ollila, Thomas, Tabiti, Bukky, Roy, Ishan, Ma, Shuo, Winter, Jane, Pro, Barbara, Moreira, Jonathan, Danilov, Alexey V., David, Kevin, Gordon, Leo I., Epperla, Narendranath
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 26.03.2025 Springer Nature B.V Nature Publishing Group
Subjects:	692/699/1541/1990/291/1621/1915 692/699/67/1059/2325 692/700/565/251 Adult Aged Aged, 80 and over Antigens, CD19 - immunology Biomedical and Life Sciences Biomedicine Cancer Research Female Hematology Humans Immunotherapy, Adoptive - adverse effects Immunotherapy, Adoptive - methods Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - immunology Lymphoma, Large B-Cell, Diffuse - mortality Lymphoma, Large B-Cell, Diffuse - therapy Male Medical prognosis Middle Aged Oncology Prognosis Receptors, Chimeric Antigen Retrospective Studies Treatment Outcome Young Adult
ISSN:	2044-5385, 2044-5385
Online Access:	Get full text
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